IE39724L - Tetrahydroisoquinoline derivatives - Google Patents

Tetrahydroisoquinoline derivatives

Info

Publication number
IE39724L
IE39724L IE741531A IE153174A IE39724L IE 39724 L IE39724 L IE 39724L IE 741531 A IE741531 A IE 741531A IE 153174 A IE153174 A IE 153174A IE 39724 L IE39724 L IE 39724L
Authority
IE
Ireland
Prior art keywords
july
formula
tetrahydroisoquinoline derivatives
sulphamoyl
hydroxy
Prior art date
Application number
IE741531A
Other versions
IE39724B1 (en
Original Assignee
Fujisava Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP8200373A external-priority patent/JPS572707B2/ja
Priority claimed from JP8200473A external-priority patent/JPS5637983B2/ja
Priority claimed from JP8598773A external-priority patent/JPS5734275B2/ja
Application filed by Fujisava Pharmaceutical Co Ltd filed Critical Fujisava Pharmaceutical Co Ltd
Publication of IE39724L publication Critical patent/IE39724L/en
Publication of IE39724B1 publication Critical patent/IE39724B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04—Five-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
    • C07D217/16—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals substituted by oxygen atoms
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

1470675 1,2,3,4-Tetrahydroisoquinoline derivatives FUJISAWA PHARMACEUTICAL CO Ltd 19 July 1974 [20 July 1973 (2) 30 July 1973] 32206/74 Heading C2C Novel 1,2,3,4-tetrahydroisoquinoline derivatives having the formula wherein R 1 and R 2 are hydrogen or (C 1 -C 6 ) alkyl; R 3 is phenyl substituted by (C 2 -C 6 ) alkenyloxy, mercapto, (C 1 -C 6 ) alkylthio, sulphamoyl, mono- or di-substituted sulphamoyl, or a heterocyclic group; R 4 and R 5 are hydroxy or protected hydroxy and X is oxygen or sulphur, and pharmaceutically acceptable salts thereof, are prepared by reacting a compound of the formula or a salt thereof, with an aldehyde of the formula R 3 .X.CH 2 CHO. The novel compounds possess pharmaceutical properties. [GB1470675A]
IE1531/74A 1973-07-20 1974-07-19 1,2,3,4-tetrahydroisoquiinoline derivatives and the preparation thereof IE39724B1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP8200373A JPS572707B2 (en) 1973-07-20 1973-07-20
JP8200473A JPS5637983B2 (en) 1973-07-20 1973-07-20
JP8598773A JPS5734275B2 (en) 1973-07-30 1973-07-30

Publications (2)

Publication Number Publication Date
IE39724L true IE39724L (en) 1975-01-20
IE39724B1 IE39724B1 (en) 1978-12-20

Family

ID=27303776

Family Applications (1)

Application Number Title Priority Date Filing Date
IE1531/74A IE39724B1 (en) 1973-07-20 1974-07-19 1,2,3,4-tetrahydroisoquiinoline derivatives and the preparation thereof

Country Status (11)

Country Link
AR (1) AR204327A1 (en)
CA (1) CA1035359A (en)
CH (1) CH605775A5 (en)
DE (1) DE2434310A1 (en)
DK (1) DK389874A (en)
ES (1) ES428442A1 (en)
FR (1) FR2237634B1 (en)
GB (1) GB1470675A (en)
IE (1) IE39724B1 (en)
NL (1) NL7409805A (en)
SE (1) SE420600B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5734275B2 (en) * 1973-07-30 1982-07-22
GB8807922D0 (en) * 1988-04-05 1988-05-05 Fujisawa Pharmaceutical Co Isoquinoline compound & process for preparation thereof
GB8921304D0 (en) * 1989-09-20 1989-11-08 Wyeth John & Brother Ltd New method of treatment and heterocyclic compounds used therein

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1145254A (en) * 1965-03-18 1969-03-12 Bristol Myers Co Novel tetrahydroisoquinoline derivatives and a process for the preparation thereof
US3389141A (en) * 1966-05-16 1968-06-18 Bristol Myers Co 1-beta-aryloxyethyltetrahydro-isoquinolines
FR2119989B1 (en) * 1970-12-29 1975-10-10 Fujisawa Pharmaceutical Co

Also Published As

Publication number Publication date
IE39724B1 (en) 1978-12-20
DK389874A (en) 1975-03-17
SE7409470L (en) 1975-01-21
DE2434310A1 (en) 1975-02-06
FR2237634B1 (en) 1978-06-30
FR2237634A1 (en) 1975-02-14
CA1035359A (en) 1978-07-25
AR204327A1 (en) 1975-12-22
GB1470675A (en) 1977-04-21
SE420600B (en) 1981-10-19
CH605775A5 (en) 1978-10-13
AU7145674A (en) 1976-01-22
ES428442A1 (en) 1977-01-01
NL7409805A (en) 1975-01-22

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