IE38387B1 - Phenylguanidine derivatives their production and their medicinal use - Google Patents
Phenylguanidine derivatives their production and their medicinal useInfo
- Publication number
- IE38387B1 IE38387B1 IE1854/73A IE185473A IE38387B1 IE 38387 B1 IE38387 B1 IE 38387B1 IE 1854/73 A IE1854/73 A IE 1854/73A IE 185473 A IE185473 A IE 185473A IE 38387 B1 IE38387 B1 IE 38387B1
- Authority
- IE
- Ireland
- Prior art keywords
- carbon atoms
- radical
- radicals
- alkyl
- optionally carrying
- Prior art date
Links
- QRJZGVVKGFIGLI-UHFFFAOYSA-N 2-phenylguanidine Chemical class NC(=N)NC1=CC=CC=C1 QRJZGVVKGFIGLI-UHFFFAOYSA-N 0.000 title abstract 2
- -1 alkyl radical Chemical group 0.000 abstract 35
- 125000004432 carbon atom Chemical group C* 0.000 abstract 28
- 125000001424 substituent group Chemical group 0.000 abstract 9
- 125000005843 halogen group Chemical group 0.000 abstract 8
- 150000001875 compounds Chemical class 0.000 abstract 4
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 3
- 150000003254 radicals Chemical class 0.000 abstract 3
- 239000005864 Sulphur Chemical group 0.000 abstract 1
- CIUQDSCDWFSTQR-UHFFFAOYSA-N [C]1=CC=CC=C1 Chemical compound [C]1=CC=CC=C1 CIUQDSCDWFSTQR-UHFFFAOYSA-N 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 230000000507 anthelmentic effect Effects 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 150000005840 aryl radicals Chemical class 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical group [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 239000003085 diluting agent Substances 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 125000000951 phenoxy group Chemical group [H]C1=C([H])C([H])=C(O*)C([H])=C1[H] 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- 238000011200 topical administration Methods 0.000 abstract 1
- 230000000699 topical effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C281/00—Derivatives of carbonic acid containing functional groups covered by groups C07C269/00 - C07C279/00 in which at least one nitrogen atom of these functional groups is further bound to another nitrogen atom not being part of a nitro or nitroso group
- C07C281/16—Compounds containing any of the groups, e.g. aminoguanidine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C277/00—Preparation of guanidine or its derivatives, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/20—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylguanidines
- C07C279/24—Y being a hetero atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Furan Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2250911A DE2250911A1 (de) | 1972-10-18 | 1972-10-18 | Phenylguanidin-derivate, ein verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE38387L IE38387L (en) | 1974-04-18 |
| IE38387B1 true IE38387B1 (en) | 1978-03-01 |
Family
ID=5859304
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE1854/73A IE38387B1 (en) | 1972-10-18 | 1973-10-17 | Phenylguanidine derivatives their production and their medicinal use |
Country Status (23)
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2651467A1 (de) * | 1976-11-11 | 1978-05-18 | Bayer Ag | Substituierte o-phenylendiaminderivate, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel |
| US6593466B1 (en) | 1999-07-07 | 2003-07-15 | Isis Pharmaceuticals, Inc. | Guanidinium functionalized nucleotides and precursors thereof |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2108835A1 (en) * | 1970-10-09 | 1972-05-26 | Rhone Poulenc Sa | Fungicidal guanidines from o phenylenediamine |
| DE2109454A1 (en) * | 1971-02-27 | 1972-09-14 | Farbenfabriken Bayer Ag, 5090 Leverkusen | Fungicidal n-(2-acylaminophenyl)-n,n-bis(alkoxycarbonyl)-guanidines - from 2-acrylaminoanilines and s-alkyl n,n-bis(alkoxycarbonyl) isothiazole |
-
1972
- 1972-10-18 DE DE2250911A patent/DE2250911A1/de active Pending
-
1973
- 1973-10-12 SU SU1963844A patent/SU489315A3/ru active
- 1973-10-15 NL NL7314183A patent/NL7314183A/xx not_active Application Discontinuation
- 1973-10-16 IL IL43431A patent/IL43431A/en unknown
- 1973-10-16 AT AT878973A patent/AT338818B/de not_active IP Right Cessation
- 1973-10-16 LU LU68627A patent/LU68627A1/xx unknown
- 1973-10-16 EG EG403A patent/EG11195A/xx active
- 1973-10-16 JP JP48115397A patent/JPS4971123A/ja active Pending
- 1973-10-16 AR AR250542A patent/AR199121A1/es active
- 1973-10-16 CS CS7129A patent/CS168049B2/cs unknown
- 1973-10-16 CH CH1465073A patent/CH586195A5/xx not_active IP Right Cessation
- 1973-10-16 JP JP48115396A patent/JPS4986341A/ja active Pending
- 1973-10-17 ZA ZA738075*A patent/ZA738075B/xx unknown
- 1973-10-17 CA CA183,615A patent/CA992554A/en not_active Expired
- 1973-10-17 PH PH15116A patent/PH10760A/en unknown
- 1973-10-17 BE BE136796A patent/BE806201A/xx unknown
- 1973-10-17 ES ES419721A patent/ES419721A1/es not_active Expired
- 1973-10-17 GB GB4838673A patent/GB1414244A/en not_active Expired
- 1973-10-17 IE IE1854/73A patent/IE38387B1/xx unknown
- 1973-10-17 AU AU61505/73A patent/AU475701B2/en not_active Expired
- 1973-10-17 SE SE7314109A patent/SE386436B/xx unknown
- 1973-10-18 FR FR7337211A patent/FR2203631B1/fr not_active Expired
- 1973-10-18 HU HUBA2987A patent/HU166358B/hu unknown
-
1976
- 1976-05-18 KE KE2628*UA patent/KE2628A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| FR2203631B1 (enrdf_load_stackoverflow) | 1977-09-09 |
| EG11195A (en) | 1977-11-30 |
| NL7314183A (enrdf_load_stackoverflow) | 1974-04-22 |
| ES419721A1 (es) | 1976-03-01 |
| IE38387L (en) | 1974-04-18 |
| SE386436B (sv) | 1976-08-09 |
| SU489315A3 (ru) | 1975-10-25 |
| LU68627A1 (enrdf_load_stackoverflow) | 1973-12-27 |
| KE2628A (en) | 1976-05-28 |
| IL43431A (en) | 1976-04-30 |
| ZA738075B (en) | 1974-08-28 |
| GB1414244A (en) | 1975-11-19 |
| CA992554A (en) | 1976-07-06 |
| JPS4971123A (enrdf_load_stackoverflow) | 1974-07-10 |
| AT338818B (de) | 1977-09-12 |
| CH586195A5 (enrdf_load_stackoverflow) | 1977-03-31 |
| AR199121A1 (es) | 1974-08-08 |
| BE806201A (fr) | 1974-04-17 |
| DE2250911A1 (de) | 1974-04-25 |
| AU6150573A (en) | 1975-04-17 |
| JPS4986341A (enrdf_load_stackoverflow) | 1974-08-19 |
| CS168049B2 (enrdf_load_stackoverflow) | 1976-05-28 |
| HU166358B (enrdf_load_stackoverflow) | 1975-03-28 |
| IL43431A0 (en) | 1974-01-14 |
| AU475701B2 (en) | 1976-09-02 |
| ATA878973A (de) | 1977-01-15 |
| FR2203631A1 (enrdf_load_stackoverflow) | 1974-05-17 |
| PH10760A (en) | 1977-09-02 |
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