IE37905B1 - A process for producing 7-acylamino-3-methyl-3-cephem-4-carboxylic acids - Google Patents
A process for producing 7-acylamino-3-methyl-3-cephem-4-carboxylic acidsInfo
- Publication number
- IE37905B1 IE37905B1 IE1182/73A IE118273A IE37905B1 IE 37905 B1 IE37905 B1 IE 37905B1 IE 1182/73 A IE1182/73 A IE 1182/73A IE 118273 A IE118273 A IE 118273A IE 37905 B1 IE37905 B1 IE 37905B1
- Authority
- IE
- Ireland
- Prior art keywords
- acid
- group
- acylamino
- alkyl
- cephem
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 abstract 4
- 239000002253 acid Substances 0.000 abstract 4
- 125000000217 alkyl group Chemical group 0.000 abstract 4
- 125000003277 amino group Chemical group 0.000 abstract 3
- 239000003054 catalyst Substances 0.000 abstract 3
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 3
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical group [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 2
- 229910000147 aluminium phosphate Inorganic materials 0.000 abstract 2
- 125000000852 azido group Chemical group *N=[N+]=[N-] 0.000 abstract 2
- 125000005843 halogen group Chemical group 0.000 abstract 2
- 125000000623 heterocyclic group Chemical group 0.000 abstract 2
- 150000003568 thioethers Chemical class 0.000 abstract 2
- 229930186147 Cephalosporin Natural products 0.000 abstract 1
- MYMOFIZGZYHOMD-UHFFFAOYSA-N Dioxygen Chemical compound O=O MYMOFIZGZYHOMD-UHFFFAOYSA-N 0.000 abstract 1
- 239000002841 Lewis acid Substances 0.000 abstract 1
- UCKMPCXJQFINFW-UHFFFAOYSA-N Sulphide Chemical compound [S-2] UCKMPCXJQFINFW-UHFFFAOYSA-N 0.000 abstract 1
- 239000005864 Sulphur Substances 0.000 abstract 1
- 150000007513 acids Chemical class 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000000304 alkynyl group Chemical group 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 229940124587 cephalosporin Drugs 0.000 abstract 1
- 150000001780 cephalosporins Chemical class 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 150000002148 esters Chemical group 0.000 abstract 1
- 238000010438 heat treatment Methods 0.000 abstract 1
- 229910052500 inorganic mineral Inorganic materials 0.000 abstract 1
- 150000007517 lewis acids Chemical class 0.000 abstract 1
- 239000011707 mineral Substances 0.000 abstract 1
- 150000007522 mineralic acids Chemical class 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- -1 phenyloxy group Chemical group 0.000 abstract 1
- 229920006395 saturated elastomer Polymers 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- BDHFUVZGWQCTTF-UHFFFAOYSA-N sulfonic acid Chemical compound OS(=O)=O BDHFUVZGWQCTTF-UHFFFAOYSA-N 0.000 abstract 1
- RAOIDOHSFRTOEL-UHFFFAOYSA-N tetrahydrothiophene Chemical compound C1CCSC1 RAOIDOHSFRTOEL-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/02—Preparation
- C07D501/08—Preparation by forming the ring or condensed ring systems
- C07D501/10—Preparation by forming the ring or condensed ring systems from compounds containing the penicillin ring system
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Cephalosporin Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP47087816A JPS4943999A (en, 2012) | 1972-09-01 | 1972-09-01 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE37905L IE37905L (en) | 1974-03-01 |
| IE37905B1 true IE37905B1 (en) | 1977-11-09 |
Family
ID=13925483
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE1182/73A IE37905B1 (en) | 1972-09-01 | 1973-07-12 | A process for producing 7-acylamino-3-methyl-3-cephem-4-carboxylic acids |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US3890314A (en, 2012) |
| JP (1) | JPS4943999A (en, 2012) |
| CH (1) | CH579575A5 (en, 2012) |
| DE (1) | DE2344130A1 (en, 2012) |
| FR (1) | FR2197888B1 (en, 2012) |
| GB (1) | GB1390581A (en, 2012) |
| IE (1) | IE37905B1 (en, 2012) |
| NL (1) | NL7311919A (en, 2012) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS536158B2 (en, 2012) * | 1972-03-23 | 1978-03-04 | ||
| US3953440A (en) * | 1974-12-13 | 1976-04-27 | Eli Lilly And Company | Deacetoxycephalosporins via penicillin sulfoxide rearrangement |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2116182A (en) * | 1935-03-01 | 1938-05-03 | Ig Farbenindustrie Ag | Production of mercaptans |
| US2378968A (en) * | 1942-12-05 | 1945-06-26 | Phillips Petroleum Co | Boron fluoride recovery process |
| US3275626A (en) * | 1962-07-31 | 1966-09-27 | Lilly Co Eli | Penicillin conversion via sulfoxide |
| US3786128A (en) * | 1968-09-30 | 1974-01-15 | Nat Distillers Chem Corp | Purification of beryllium hydride |
| HU168215B (en, 2012) * | 1969-03-11 | 1976-03-28 | ||
| US3647787A (en) * | 1969-07-02 | 1972-03-07 | Lilly Co Eli | Process improvement for converting penicillin sulfoxide esters to cephem compounds |
| GB1312233A (en) * | 1969-12-05 | 1973-04-04 | Glaxo Lab Ltd | Cephalosporin compounds |
-
1972
- 1972-09-01 JP JP47087816A patent/JPS4943999A/ja active Pending
-
1973
- 1973-07-12 IE IE1182/73A patent/IE37905B1/xx unknown
- 1973-07-18 GB GB3419273A patent/GB1390581A/en not_active Expired
- 1973-08-07 US US386355A patent/US3890314A/en not_active Expired - Lifetime
- 1973-08-30 NL NL7311919A patent/NL7311919A/xx unknown
- 1973-08-31 FR FR7331587A patent/FR2197888B1/fr not_active Expired
- 1973-08-31 CH CH1254673A patent/CH579575A5/xx not_active IP Right Cessation
- 1973-09-01 DE DE19732344130 patent/DE2344130A1/de active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| NL7311919A (en, 2012) | 1974-03-05 |
| GB1390581A (en) | 1975-04-16 |
| DE2344130A1 (de) | 1974-03-14 |
| US3890314A (en) | 1975-06-17 |
| CH579575A5 (en, 2012) | 1976-09-15 |
| JPS4943999A (en, 2012) | 1974-04-25 |
| FR2197888B1 (en, 2012) | 1976-10-01 |
| FR2197888A1 (en, 2012) | 1974-03-29 |
| IE37905L (en) | 1974-03-01 |
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