IE37007B1 - Tricyclic compounds having antiallergic properties and pharmaceutical compositions thereof - Google Patents

Tricyclic compounds having antiallergic properties and pharmaceutical compositions thereof

Info

Publication number
IE37007B1
IE37007B1 IE1220/72A IE122072A IE37007B1 IE 37007 B1 IE37007 B1 IE 37007B1 IE 1220/72 A IE1220/72 A IE 1220/72A IE 122072 A IE122072 A IE 122072A IE 37007 B1 IE37007 B1 IE 37007B1
Authority
IE
Ireland
Prior art keywords
pharmaceutical compositions
tricyclic compounds
compounds
antiallergic properties
formula
Prior art date
Application number
IE1220/72A
Other versions
IE37007L (en
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB860872*[A external-priority patent/GB1414621A/en
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of IE37007L publication Critical patent/IE37007L/en
Publication of IE37007B1 publication Critical patent/IE37007B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78—Ring systems having three or more relevant rings
    • C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans
    • C07D311/82—Xanthenes
    • C07D311/84—Xanthenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 9
    • C07D311/86—Oxygen atoms, e.g. xanthones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/49—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
    • C07C205/57—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C07C205/58—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton the carbon skeleton being further substituted by halogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/647—Unsaturated compounds containing a keto groups being part of a ring having unsaturation outside the ring
    • C07C49/653—Unsaturated compounds containing a keto groups being part of a ring having unsaturation outside the ring polycyclic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/41—Preparation of salts of carboxylic acids
    • C07C51/412—Preparation of salts of carboxylic acids by conversion of the acids, their salts, esters or anhydrides with the same carboxylic acid part
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C65/32—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing keto groups
    • C07C65/34—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing keto groups polycyclic
    • C07C65/36—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing keto groups polycyclic containing rings other than six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C65/32—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing keto groups
    • C07C65/40—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing keto groups containing singly bound oxygen-containing groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C66/00—Quinone carboxylic acids
    • C07C66/02—Anthraquinone carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
    • C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • C07D219/06—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/02—Ortho- or ortho- and peri-condensed systems
    • C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
    • C07C2603/06—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members
    • C07C2603/10—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings
    • C07C2603/12—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings only one five-membered ring
    • C07C2603/18—Fluorenes; Hydrogenated fluorenes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Pyrane Compounds (AREA)

Abstract

Tricyclic compounds of the formula 1, in which the symbols Z<1> to Z<3> have the meaning given in Patent Claim 1, are prepared by oxidising compounds of the formula 2, in which the symbols Y<1> to Y<4> have the meaning given in Patent Claim 1. The compounds of the formula 1 are intended for preparing drugs which are suitable for treating allergic reactions in humans or in mammalian animals. <IMAGE> [FR2154476A1]
IE1220/72A 1971-09-08 1972-09-07 Tricyclic compounds having antiallergic properties and pharmaceutical compositions thereof IE37007B1 (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
GB4185271 1971-09-08
GB860872*[A GB1414621A (en) 1971-09-08 1972-02-24 Tricyclic compounds having antiallergic properties and pharmaceuti cal compositions thereof
GB861072 1972-02-24
GB860972 1972-02-24
GB1490972 1972-03-29
GB3581872 1972-08-01
GB4007972 1972-08-29

Publications (2)

Publication Number Publication Date
IE37007L IE37007L (en) 1973-03-08
IE37007B1 true IE37007B1 (en) 1977-04-13

Family

ID=27562567

Family Applications (1)

Application Number Title Priority Date Filing Date
IE1220/72A IE37007B1 (en) 1971-09-08 1972-09-07 Tricyclic compounds having antiallergic properties and pharmaceutical compositions thereof

Country Status (11)

Country Link
JP (1) JPS4834865A (en)
AR (1) AR209571A1 (en)
BE (1) BE788514A (en)
CH (1) CH630885A5 (en)
DD (2) DD114946A5 (en)
DE (1) DE2243997A1 (en)
FR (1) FR2154476B1 (en)
IE (1) IE37007B1 (en)
IL (1) IL40320A (en)
LU (1) LU66018A1 (en)
NL (1) NL7212174A (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55122785A (en) * 1979-03-15 1980-09-20 Yoshitomi Pharmaceut Ind Ltd Preparation of benzopyranopyridine derivative
FR2464937A1 (en) * 1979-09-13 1981-03-20 Interox PROCESS FOR THE MANUFACTURE OF SUBSTITUTED ANTHRAQUINONES
US4585876A (en) * 1982-11-25 1986-04-29 Ciba-Geigy Corporation Novel xanthones and thioxanthones
JPS59175840A (en) * 1983-03-24 1984-10-04 イカリ消毒株式会社 Extermination of underground small animals
JPS6034901A (en) * 1984-06-04 1985-02-22 Nippon Nohyaku Co Ltd Prevention and extermination of insect pest, etc.
US4714669A (en) * 1985-04-11 1987-12-22 Ciba-Geigy Corporation Radiation-sensitive polycondensates, their preparation, material coated therewith and the use thereof
TW200301698A (en) 2001-12-21 2003-07-16 Bristol Myers Squibb Co Acridone inhibitors of IMPDH enzyme
CN1748675A (en) * 2005-07-11 2006-03-22 丛晓东 Composition of rheinic acid compounds and preparing method and use for treating diabetes

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1833272A (en) * 1928-06-21 1931-11-24 Gen Aniline Works Inc Beta-anthraquinone-carboxylic acids and the esters thereof and process of preparing them
DE495100C (en) * 1928-06-22 1930-04-07 I G Farbenindustrie Akt Ges Process for the preparation of ª ‰ -Anthraquinone carboxylic acids and their esters
NL7008621A (en) * 1969-06-25 1970-12-29
US3642997A (en) * 1969-06-25 1972-02-15 Merck & Co Inc Tricyclic carboxylic acids in the treatment of inflammation
US3873538A (en) * 1970-08-05 1975-03-25 Allen & Hanburys Ltd Amino-9,10-dihydro-9,10-dioxo-2-anthroic acids

Also Published As

Publication number Publication date
FR2154476A1 (en) 1973-05-11
NL7212174A (en) 1973-03-12
DE2243997A1 (en) 1973-03-15
DD114946A5 (en) 1975-09-05
CH630885A5 (en) 1982-07-15
BE788514A (en) 1973-03-07
JPS4834865A (en) 1973-05-22
IE37007L (en) 1973-03-08
AR209571A1 (en) 1977-05-13
IL40320A (en) 1976-12-31
FR2154476B1 (en) 1975-10-17
LU66018A1 (en) 1973-03-12
IL40320A0 (en) 1972-11-28
DD106263A5 (en) 1974-06-12
AU4640672A (en) 1974-03-14

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