IE36213B1 - 1,3-dihydro-3-hydroxy-5-phenyl-2h-1,4-benzodiazepin-2-one,substituted diamino acetate esters and their acid salts - Google Patents

1,3-dihydro-3-hydroxy-5-phenyl-2h-1,4-benzodiazepin-2-one,substituted diamino acetate esters and their acid salts

Info

Publication number
IE36213B1
IE36213B1 IE375/72A IE37572A IE36213B1 IE 36213 B1 IE36213 B1 IE 36213B1 IE 375/72 A IE375/72 A IE 375/72A IE 37572 A IE37572 A IE 37572A IE 36213 B1 IE36213 B1 IE 36213B1
Authority
IE
Ireland
Prior art keywords
benzodiazepin
dihydro
hydroxy
phenyl
acid salts
Prior art date
Application number
IE375/72A
Other languages
English (en)
Other versions
IE36213L (en
Original Assignee
American Home Prod
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Home Prod filed Critical American Home Prod
Publication of IE36213L publication Critical patent/IE36213L/xx
Publication of IE36213B1 publication Critical patent/IE36213B1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IE375/72A 1971-03-30 1972-03-23 1,3-dihydro-3-hydroxy-5-phenyl-2h-1,4-benzodiazepin-2-one,substituted diamino acetate esters and their acid salts IE36213B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12963871A 1971-03-30 1971-03-30
US05/223,712 US4065451A (en) 1971-03-30 1972-02-04 1,3-Dihydro-3-hydroxy-5-phenyl-2H-1,4-benzodiazepin-2-one, substituted diamino acetate esters and their acid salts

Publications (2)

Publication Number Publication Date
IE36213L IE36213L (en) 1972-09-30
IE36213B1 true IE36213B1 (en) 1976-09-15

Family

ID=26827785

Family Applications (1)

Application Number Title Priority Date Filing Date
IE375/72A IE36213B1 (en) 1971-03-30 1972-03-23 1,3-dihydro-3-hydroxy-5-phenyl-2h-1,4-benzodiazepin-2-one,substituted diamino acetate esters and their acid salts

Country Status (7)

Country Link
US (1) US4065451A (enExample)
JP (1) JPS5724347B1 (enExample)
CH (1) CH583209A5 (enExample)
DE (1) DE2215440A1 (enExample)
FR (1) FR2132195B1 (enExample)
GB (1) GB1351549A (enExample)
IE (1) IE36213B1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT361492B (de) * 1978-12-18 1981-03-10 Gerot Pharmazeutika Verfahren zur herstellung von neuen 3-hydroxy- 1,4-benzodiazepin-2-onen
IT1165588B (it) * 1983-03-23 1987-04-22 Medosan Ind Biochimi 1,4 benzodiazepine terapeuticamente attive
CA1332410C (en) * 1984-06-26 1994-10-11 Roger M. Freidinger Benzodiazepine analogs
US4820834A (en) * 1984-06-26 1989-04-11 Merck & Co., Inc. Benzodiazepine analogs
EP3468545A4 (en) 2016-06-08 2020-07-22 President and Fellows of Harvard College METHODS AND COMPOSITIONS FOR REDUCING TACTILE DYSFUNCTION AND ANXIETY ASSOCIATED WITH AUTISM SPECTRUM DISORDER, RETT SYNDROME AND FRAGILE X SYNDROME
EP3797097A4 (en) 2018-05-22 2022-03-09 President and Fellows of Harvard College Compositions and methods for reducing tactile dysfunction, anxiety, and social impairment
US11434244B2 (en) 2018-05-29 2022-09-06 President And Fellows Of Harvard College Compositions and methods for reducing tactile dysfunction, anxiety, and social impairment
EP3946390A4 (en) 2019-03-25 2022-12-21 President and Fellows of Harvard College COMPOSITIONS AND METHODS TO REDUCE TACTILE DYSFUNCTION, ANXIETY AND SOCIAL DISABILITIES

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL298071A (enExample) * 1963-06-04
FR135F (enExample) * 1964-08-13

Also Published As

Publication number Publication date
US4065451A (en) 1977-12-27
GB1351549A (en) 1974-05-01
FR2132195A1 (enExample) 1972-11-17
CH583209A5 (enExample) 1976-12-31
JPS5724347B1 (enExample) 1982-05-24
FR2132195B1 (enExample) 1976-07-02
IE36213L (en) 1972-09-30
DE2215440A1 (de) 1972-10-19

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