IE35734L - Producing mutanase - Google Patents
Producing mutanaseInfo
- Publication number
- IE35734L IE35734L IE711294A IE129471A IE35734L IE 35734 L IE35734 L IE 35734L IE 711294 A IE711294 A IE 711294A IE 129471 A IE129471 A IE 129471A IE 35734 L IE35734 L IE 35734L
- Authority
- IE
- Ireland
- Prior art keywords
- mutanase
- alpha
- glucan
- dental plaque
- producing
- Prior art date
Links
- 108010000165 exo-1,3-alpha-glucanase Proteins 0.000 title abstract 4
- 208000002064 Dental Plaque Diseases 0.000 abstract 2
- 108090000790 Enzymes Proteins 0.000 abstract 1
- 102000004190 Enzymes Human genes 0.000 abstract 1
- 229920001503 Glucan Polymers 0.000 abstract 1
- 241000228143 Penicillium Species 0.000 abstract 1
- 241000194017 Streptococcus Species 0.000 abstract 1
- 241000223259 Trichoderma Species 0.000 abstract 1
- 238000012258 culturing Methods 0.000 abstract 1
- 150000004676 glycans Chemical class 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
- 239000011159 matrix material Substances 0.000 abstract 1
- 244000005700 microbiome Species 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 229920005640 poly alpha-1,3-glucan Polymers 0.000 abstract 1
- 229920001282 polysaccharide Polymers 0.000 abstract 1
- 239000005017 polysaccharide Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/66—Enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
- C12N9/2405—Glucanases
- C12N9/2408—Glucanases acting on alpha -1,4-glucosidic bonds
- C12N9/2411—Amylases
- C12N9/2428—Glucan 1,4-alpha-glucosidase (3.2.1.3), i.e. glucoamylase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
- C12Y302/01059—Glucan endo-1,3-alpha-glucosidase (3.2.1.59)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
- C12Y302/01084—Glucan 1,3-alpha-glucosidase (3.2.1.84), i.e. mutanase
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/885—Streptococcus
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Birds (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Cosmetics (AREA)
- Enzymes And Modification Thereof (AREA)
- Bag Frames (AREA)
Abstract
This invention relates to a class of alpha 1,3 glucan 3-glucanohydrolase named mutanase. The alpha 1,3 glucosidic bonded polysaccharides hydrolyzed by these enzymes, herein termed mutan, forms part of the matrix material of dental plaque. Mutanase may be produced by culturing microorganisms such as, Trichoderma, Penicillium, or Streptococcus on a glucan characterized by at least 50% alpha -1, 3 glucosidic bonds. Mutanase containing compositions are adapted for disintegrating in vivo essential structural components of dental plaque.
[US4353891A]
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB5071270A GB1373487A (en) | 1970-10-26 | 1970-10-26 | Enzymes their preparation and uses |
Publications (2)
Publication Number | Publication Date |
---|---|
IE35734L true IE35734L (en) | 1972-04-26 |
IE35734B1 IE35734B1 (en) | 1976-05-12 |
Family
ID=10457044
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IE1294/71A IE35734B1 (en) | 1970-10-26 | 1971-10-15 | Improvements in or relating to enzymes their preparation and uses |
Country Status (19)
Country | Link |
---|---|
US (1) | US4353891A (en) |
JP (1) | JPS5645587B1 (en) |
AT (2) | AT318815B (en) |
AU (1) | AU468059B2 (en) |
BE (1) | BE774420A (en) |
CA (1) | CA996877A (en) |
CH (1) | CH571571A5 (en) |
DE (1) | DE2152620C3 (en) |
DK (1) | DK131874C (en) |
ES (1) | ES396270A1 (en) |
FI (1) | FI49311C (en) |
FR (1) | FR2110067A5 (en) |
GB (1) | GB1373487A (en) |
IE (1) | IE35734B1 (en) |
IT (1) | IT1043849B (en) |
NL (1) | NL175734C (en) |
NO (1) | NO135147C (en) |
SE (2) | SE400091B (en) |
ZA (1) | ZA716878B (en) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2184432A1 (en) * | 1972-05-17 | 1973-12-28 | Choay Sa | Alpha-glucan-hydrolases - for use in destruction of dental plaque |
US4328313A (en) * | 1979-12-19 | 1982-05-04 | The United States Of America As Represented By The Secretary Of The Navy | Method of producing a plaque dispersing enzyme |
US4340673A (en) * | 1980-11-07 | 1982-07-20 | Merck & Co., Inc. | Process of producing modified glucans as anti-caries agent |
NZ199891A (en) * | 1981-03-04 | 1985-07-31 | Univ Melbourne | Caries-inhibiting compositions containing casein or x-s-casein or phosuitin |
JPS57165312A (en) | 1981-04-03 | 1982-10-12 | Handai Biseibutsubiyou Kenkyukai | Production of oral composition |
ZA823690B (en) * | 1981-06-11 | 1983-03-30 | Novo Industri As | Enzymatic treatment of wine and must |
JPS58134014A (en) * | 1982-02-03 | 1983-08-10 | Rooto Seiyaku Kk | Composition for cleaning denture |
FR2551087B1 (en) * | 1983-08-30 | 1986-03-21 | Rhone Poulenc Spec Chim | PROCESS FOR TREATING POLYSACCHARIDE SOLUTION AND USE THEREOF |
US4731245A (en) * | 1983-12-29 | 1988-03-15 | Kitasato Kenkyusho | Vaccine, antigen and antibody for treating microorganisms of the MCLS-type streptococcus sanguis |
GB8823277D0 (en) * | 1988-10-04 | 1988-11-09 | Schering Agrochemicals Ltd | Fungicidal composition |
US5190746A (en) * | 1989-05-10 | 1993-03-02 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Plaque inhibiting oligosaccharide |
US5071977A (en) * | 1989-05-10 | 1991-12-10 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Plaque inhibiting oligosaccharide |
CN1213403A (en) * | 1996-02-09 | 1999-04-07 | 诺沃诺尔迪斯克生物技术有限公司 | Polypeptides having mutanase activity and nucleic acids encoding same |
WO1997038669A1 (en) * | 1996-04-16 | 1997-10-23 | Novo Nordisk A/S | Compositions for the removal of dental plaque |
EP0954570A1 (en) * | 1996-06-28 | 1999-11-10 | Novo Nordisk A/S | A recombinant enzyme with mutanase activity |
AU4616797A (en) * | 1996-10-25 | 1998-05-22 | Novo Nordisk A/S | An oral care product comprising a mutan binding domain |
US5871714A (en) * | 1997-10-16 | 1999-02-16 | Pharmacal Biotechnologies, Inc. | Compositions for controlling bacterial colonization |
US6413501B2 (en) | 1997-10-17 | 2002-07-02 | Novozymes A/S | Plaque-inhibiting oral compositions |
WO2000066616A1 (en) * | 1999-05-03 | 2000-11-09 | Advanced Research & Technology Institute, Inc. | METHODS AND COMPOSITIONS FOR CONTROLLING DENTAL CARIES, AND RECOMBINANT SmaA POLYPEPTIDES USEFUL FOR SAME |
DE60123841T2 (en) * | 2000-08-01 | 2007-05-16 | Charm Sciences, Inc., Lawrence | HYGIENE MONITORING |
US7354569B2 (en) * | 2003-07-11 | 2008-04-08 | Colgate-Palmolive Company | Chewable antiplaque confectionery dental composition |
EP1634948A1 (en) | 2004-09-10 | 2006-03-15 | Basf Aktiengesellschaft | Means and methods for preventing and/or treating caries |
WO2006091118A2 (en) * | 2005-02-28 | 2006-08-31 | Uniwersytet Marii Curie-Sklodowskiej | A NEW STRAIN OF PAENIBACILLUS CURDLANOLYTICUS, A METHOD OF MUTANASE PRODUCTION, THE APPLICATION OF α-L ,3-GLUCAN FOR THE PRODUCTION OF MUTANASE, AND AN ENZYMATIC PREPARATION |
CA2671507A1 (en) | 2006-12-19 | 2008-06-26 | Basf Se | Uses and methods for preventing and/or treating caries caused by mutans streptococci |
US20100330000A1 (en) * | 2007-11-06 | 2010-12-30 | Kristian Hellgren | Enzymes for treatment of gingivitis |
US8709386B2 (en) * | 2008-04-11 | 2014-04-29 | Danisco Us Inc. | Method of making and using an alpha-glucanase composition to reduce or remove biofilm |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3686393A (en) * | 1970-02-12 | 1972-08-22 | Merck & Co Inc | Method for inhibiting dental plaque |
US3622661A (en) * | 1970-07-13 | 1971-11-23 | Colgate Palmolive Co | Oral preparations |
-
1970
- 1970-10-26 GB GB5071270A patent/GB1373487A/en not_active Expired
-
1971
- 1971-10-14 ZA ZA716878A patent/ZA716878B/en unknown
- 1971-10-15 IE IE1294/71A patent/IE35734B1/en unknown
- 1971-10-19 AU AU34743/71A patent/AU468059B2/en not_active Expired
- 1971-10-19 US US05/190,621 patent/US4353891A/en not_active Expired - Lifetime
- 1971-10-19 CA CA125,575A patent/CA996877A/en not_active Expired
- 1971-10-22 DE DE2152620A patent/DE2152620C3/en not_active Expired
- 1971-10-22 FI FI713003A patent/FI49311C/en active
- 1971-10-22 ES ES396270A patent/ES396270A1/en not_active Expired
- 1971-10-22 NL NLAANVRAGE7114567,A patent/NL175734C/en not_active IP Right Cessation
- 1971-10-23 IT IT63673/71A patent/IT1043849B/en active
- 1971-10-25 DK DK517671A patent/DK131874C/en active
- 1971-10-25 NO NO3950/71A patent/NO135147C/no unknown
- 1971-10-25 AT AT1045672A patent/AT318815B/en not_active IP Right Cessation
- 1971-10-25 BE BE774420A patent/BE774420A/en not_active IP Right Cessation
- 1971-10-25 CH CH1550871A patent/CH571571A5/xx not_active IP Right Cessation
- 1971-10-25 AT AT922271A patent/AT309364B/en not_active IP Right Cessation
- 1971-10-26 FR FR7138499A patent/FR2110067A5/fr not_active Expired
- 1971-10-26 JP JP8444671A patent/JPS5645587B1/ja active Pending
- 1971-10-26 SE SE7113596A patent/SE400091B/en unknown
-
1977
- 1977-10-18 SE SE7711735A patent/SE426650B/en not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
DK131874C (en) | 1976-02-16 |
NO135147B (en) | 1976-11-08 |
CA996877A (en) | 1976-09-14 |
GB1373487A (en) | 1974-11-13 |
AU3474371A (en) | 1973-05-03 |
BE774420A (en) | 1972-04-25 |
AU468059B2 (en) | 1975-12-18 |
IE35734B1 (en) | 1976-05-12 |
NL7114567A (en) | 1972-04-28 |
IT1043849B (en) | 1980-02-29 |
DE2152620B2 (en) | 1979-04-19 |
SE7711735L (en) | 1977-10-18 |
FI49311B (en) | 1975-01-31 |
DE2152620A1 (en) | 1972-04-27 |
CH571571A5 (en) | 1976-01-15 |
DK131874B (en) | 1975-09-15 |
DE2152620C3 (en) | 1979-12-06 |
AT318815B (en) | 1974-11-25 |
US4353891A (en) | 1982-10-12 |
SE426650B (en) | 1983-02-07 |
AT309364B (en) | 1973-08-10 |
JPS5645587B1 (en) | 1981-10-27 |
SE400091B (en) | 1978-03-13 |
ZA716878B (en) | 1972-06-28 |
NO135147C (en) | 1977-02-16 |
NL175734B (en) | 1984-07-16 |
NL175734C (en) | 1984-12-17 |
FI49311C (en) | 1975-05-12 |
FR2110067A5 (en) | 1972-05-26 |
ES396270A1 (en) | 1975-01-01 |
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