IE35669B1 - A process for the manufacture of benzodiazepine derivatives - Google Patents
A process for the manufacture of benzodiazepine derivativesInfo
- Publication number
- IE35669B1 IE35669B1 IE1200/71A IE120071A IE35669B1 IE 35669 B1 IE35669 B1 IE 35669B1 IE 1200/71 A IE1200/71 A IE 1200/71A IE 120071 A IE120071 A IE 120071A IE 35669 B1 IE35669 B1 IE 35669B1
- Authority
- IE
- Ireland
- Prior art keywords
- manufacture
- benzodiazepine derivatives
- us3681341a
- benzodiazepin
- anticonvulsants
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 229940053197 benzodiazepine derivative antiepileptics Drugs 0.000 title 1
- 125000003310 benzodiazepinyl group Chemical class N1N=C(C=CC2=C1C=CC=C2)* 0.000 title 1
- RGGLEJFUEMKQSH-UHFFFAOYSA-N 1,4-benzodiazepin-2-one Chemical class O=C1C=NC=C2C=CC=CC2=N1 RGGLEJFUEMKQSH-UHFFFAOYSA-N 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 229940125681 anticonvulsant agent Drugs 0.000 abstract 1
- 239000001961 anticonvulsive agent Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229940035363 muscle relaxants Drugs 0.000 abstract 1
- 239000003158 myorelaxant agent Substances 0.000 abstract 1
- ODUCDPQEXGNKDN-UHFFFAOYSA-N nitroxyl Chemical compound O=N ODUCDPQEXGNKDN-UHFFFAOYSA-N 0.000 abstract 1
- 230000008707 rearrangement Effects 0.000 abstract 1
- 229940125723 sedative agent Drugs 0.000 abstract 1
- 239000000932 sedative agent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
- C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
- C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
- C07D243/24—Oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10118870A | 1970-12-23 | 1970-12-23 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE35669L IE35669L (en) | 1972-06-23 |
| IE35669B1 true IE35669B1 (en) | 1976-04-14 |
Family
ID=22283420
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE1200/71A IE35669B1 (en) | 1970-12-23 | 1971-09-27 | A process for the manufacture of benzodiazepine derivatives |
Country Status (18)
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4056525A (en) * | 1975-06-02 | 1977-11-01 | American Home Products Corporation | 2,3-dialkoxy-3h-1,4-benzodiazepines |
| US5438035A (en) * | 1994-06-24 | 1995-08-01 | American Cyanamid Company | Methods for controlling undesirable plant species with benzodiazepine compounds |
| WO2006040036A1 (en) * | 2004-10-13 | 2006-04-20 | F. Hoffmann-La Roche Ag | Disubstituted pyrazolobenzodiazepines useful as inhibitors for cdk2 and angiogesis, and for the treatment of breast, colon, lung and prostate cancer |
| JP2009511535A (ja) * | 2005-10-14 | 2009-03-19 | エフ．ホフマン−ラ ロシュ アーゲー | ５−（２−クロロフェニル）−１，２−ジヒドロ−７−フルオロ−８−メトキシ−３−メチル−ピラゾロ［３，４−ｂ］［１，４］ベンゾジアゼピン |
| KR102257961B1 (ko) | 2011-11-02 | 2021-05-28 | 타지반 투 엘엘씨 | 동화상 부호화 방법, 동화상 부호화 장치, 동화상 복호 방법, 동화상 복호 장치, 및, 동화상 부호화 복호 장치 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3462418A (en) * | 1963-10-29 | 1969-08-19 | Hoffmann La Roche | Preparation of 1,4-benzodiazepin-2-one-4-oxide from 2-lower alkoxy-1,4-benzodiazepine-4-oxide |
-
1970
- 1970-12-23 US US101188A patent/US3681341A/en not_active Expired - Lifetime
-
1971
- 1971-09-17 CH CH1360171A patent/CH562811A5/xx not_active IP Right Cessation
- 1971-09-20 BE BE772818A patent/BE772818A/xx unknown
- 1971-09-20 AT AT814271A patent/AT319251B/de not_active IP Right Cessation
- 1971-09-20 SE SE7111876A patent/SE373137B/xx unknown
- 1971-09-21 NO NO3496/71A patent/NO132095C/no unknown
- 1971-09-22 DE DE19712147283 patent/DE2147283A1/de active Pending
- 1971-09-22 ZA ZA716358A patent/ZA716358B/xx unknown
- 1971-09-24 IL IL37776A patent/IL37776A0/xx unknown
- 1971-09-27 IE IE1200/71A patent/IE35669B1/xx unknown
- 1971-09-27 GB GB45004/71A patent/GB1294776A/en not_active Expired
- 1971-09-29 AU AU33991/71A patent/AU3399171A/en not_active Expired
- 1971-10-02 ES ES395622A patent/ES395622A1/es not_active Expired
- 1971-10-06 NL NL7113708A patent/NL7113708A/xx not_active Application Discontinuation
- 1971-10-08 YU YU2559/71A patent/YU34525B/xx unknown
- 1971-10-15 BR BR6876/71A patent/BR7106876D0/pt unknown
- 1971-10-15 JP JP8100471A patent/JPS5531150B1/ja active Pending
- 1971-12-23 FR FR7146454A patent/FR2119069B1/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| ZA716358B (en) | 1972-08-30 |
| ES395622A1 (es) | 1973-11-16 |
| BR7106876D0 (pt) | 1973-07-12 |
| GB1294776A (en) | 1972-11-01 |
| CH562811A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1975-06-13 |
| BE772818A (fr) | 1972-03-20 |
| AT319251B (de) | 1974-12-10 |
| IE35669L (en) | 1972-06-23 |
| AU3399171A (en) | 1973-04-05 |
| YU255971A (en) | 1979-02-28 |
| NL7113708A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1972-06-27 |
| FR2119069B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1975-06-13 |
| SE373137B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1975-01-27 |
| US3681341A (en) | 1972-08-01 |
| NO132095B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1975-06-09 |
| DE2147283A1 (de) | 1972-07-13 |
| NO132095C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1975-09-17 |
| JPS5531150B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1980-08-15 |
| YU34525B (en) | 1979-09-10 |
| FR2119069A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1972-08-04 |
| IL37776A0 (en) | 1971-11-29 |
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