IE35180B1 - Bis-basic ketones of dibenzothiophene - Google Patents
Bis-basic ketones of dibenzothiopheneInfo
- Publication number
- IE35180B1 IE35180B1 IE539/71A IE53971A IE35180B1 IE 35180 B1 IE35180 B1 IE 35180B1 IE 539/71 A IE539/71 A IE 539/71A IE 53971 A IE53971 A IE 53971A IE 35180 B1 IE35180 B1 IE 35180B1
- Authority
- IE
- Ireland
- Prior art keywords
- formula
- dibenzothiophene
- group
- prepared
- reacted
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/76—Dibenzothiophenes
Abstract
1292567 Bis basic ketones of dibenzothiophene RICHARDSON-MERRELL Inc 30 April 1971 [1 May 1970] 12495/71 Heading C2C Novel compounds of Formula Ia wherein Y is a group of Formula A wherein R 1 and R 2 are each H, C 1-6 alkyl, C 3-6 cycloalkyl or C 3-6 alkenyl in which the vinyl unsaturation is not in the 1-position; or a group of Formula B wherein n is 4, 5 or 6 and R<SP>3</SP> is H, C 1-4 alkyl, phenyl or benzyl; or a group of Formula C wherein X is -O- or R 4 N where R 4 is H or C 1-4 alkyl; or a group of Formula D wherein m is 1 or 2 and p is 2 or 3 ; or a group of Formula E wherein q is or 2 and r is 1 or 2 or also 3 if q is 1; and A is a C 1-6 straight or branched-chain alkylene radical are prepared by one of the following methods (a) a compound of formula HY is reacted with a compound of Formula F wherein Hal is halogen or (b) a dicyano dibenzothiophene is reacted with a Grignard reagent of formula HalMgAY or (c) formaldehyde and a secondary amine HY is reacted with a diacetyldibenzothiophene. Compounds of Formula F above are prepared either by a Friedel-Crafts reaction on dibenzothiophene using a reagent or where A is CH 2 by halogenation of the methyl groups of the diacetyl dibenzothiophene which may be prepared by the above reaction using a reactive ester or anhydride of acetic acid. Compounds of Formula III are prepared either by dehydration of the diamide of the corresponding dicarboxylic acid or by diazatization of the corresponding diamine followed by reaction with cuprous cyanide. Pharmaceutical compositions having antiviral activity and being in conventional forms for oral, topical, bucal, internasal or parenteral administration comprise an above novel compound or salt and a non-toxic pharmaceutical carrier.
[GB1292567A]
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US3390270A | 1970-05-01 | 1970-05-01 |
Publications (2)
Publication Number | Publication Date |
---|---|
IE35180L IE35180L (en) | 1971-11-01 |
IE35180B1 true IE35180B1 (en) | 1975-12-10 |
Family
ID=21873118
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IE539/71A IE35180B1 (en) | 1970-05-01 | 1971-04-30 | Bis-basic ketones of dibenzothiophene |
Country Status (18)
Country | Link |
---|---|
JP (1) | JPS553352B1 (en) |
AT (1) | AT302290B (en) |
BE (1) | BE766577A (en) |
CA (1) | CA950456A (en) |
CH (1) | CH560212A5 (en) |
CS (1) | CS180573B2 (en) |
DE (1) | DE2120996C3 (en) |
ES (1) | ES390707A1 (en) |
FR (1) | FR2092120B1 (en) |
GB (1) | GB1292567A (en) |
HU (1) | HU165245B (en) |
IE (1) | IE35180B1 (en) |
IL (1) | IL36644A (en) |
NL (1) | NL7105854A (en) |
NO (1) | NO131836C (en) |
PH (1) | PH9507A (en) |
SE (1) | SE387346B (en) |
ZA (1) | ZA712219B (en) |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3083201A (en) * | 1961-02-13 | 1963-03-26 | Smith Kline French Lab | Glyoxal derivatives of dibenzofuran and dibenzothiophene |
US3867409A (en) * | 1969-06-16 | 1975-02-18 | Richardson Merrell Inc | Bis-basic esters of dibenzofuran |
-
1971
- 1971-04-06 CA CA109,720,A patent/CA950456A/en not_active Expired
- 1971-04-07 ZA ZA712219A patent/ZA712219B/en unknown
- 1971-04-16 PH PH12372*UA patent/PH9507A/en unknown
- 1971-04-18 IL IL36644A patent/IL36644A/en unknown
- 1971-04-21 JP JP2533371A patent/JPS553352B1/ja active Pending
- 1971-04-26 NO NO1543/71A patent/NO131836C/no unknown
- 1971-04-27 AT AT362971A patent/AT302290B/en not_active IP Right Cessation
- 1971-04-28 SE SE7105505A patent/SE387346B/en unknown
- 1971-04-28 HU HURI428A patent/HU165245B/hu unknown
- 1971-04-28 CH CH626371A patent/CH560212A5/xx not_active IP Right Cessation
- 1971-04-29 ES ES390707A patent/ES390707A1/en not_active Expired
- 1971-04-29 DE DE2120996A patent/DE2120996C3/en not_active Expired
- 1971-04-29 NL NL7105854A patent/NL7105854A/xx unknown
- 1971-04-30 FR FR7115646A patent/FR2092120B1/fr not_active Expired
- 1971-04-30 BE BE766577A patent/BE766577A/en unknown
- 1971-04-30 IE IE539/71A patent/IE35180B1/en unknown
- 1971-04-30 GB GB02495/71A patent/GB1292567A/en not_active Expired
- 1971-04-30 CS CS7100003179A patent/CS180573B2/en unknown
Also Published As
Publication number | Publication date |
---|---|
DE2120996B2 (en) | 1979-08-02 |
IL36644A (en) | 1974-12-31 |
JPS553352B1 (en) | 1980-01-24 |
DE2120996C3 (en) | 1980-04-17 |
ES390707A1 (en) | 1973-06-16 |
HU165245B (en) | 1974-07-27 |
IE35180L (en) | 1971-11-01 |
FR2092120B1 (en) | 1974-08-23 |
DE2120996A1 (en) | 1971-11-18 |
AT302290B (en) | 1972-10-10 |
GB1292567A (en) | 1972-10-11 |
NL7105854A (en) | 1971-11-03 |
ZA712219B (en) | 1972-01-26 |
BE766577A (en) | 1971-09-16 |
CA950456A (en) | 1974-07-02 |
SE387346B (en) | 1976-09-06 |
CS180573B2 (en) | 1978-01-31 |
CH560212A5 (en) | 1975-03-27 |
PH9507A (en) | 1976-01-09 |
FR2092120A1 (en) | 1972-01-21 |
NO131836B (en) | 1975-05-05 |
IL36644A0 (en) | 1971-06-23 |
NO131836C (en) | 1975-08-13 |
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