IE35059B1 - 21-fluoro-3,16,17-trihydroxy-pregnane compounds and their derivatives - Google Patents
21-fluoro-3,16,17-trihydroxy-pregnane compounds and their derivativesInfo
- Publication number
- IE35059B1 IE35059B1 IE458/71A IE45871A IE35059B1 IE 35059 B1 IE35059 B1 IE 35059B1 IE 458/71 A IE458/71 A IE 458/71A IE 45871 A IE45871 A IE 45871A IE 35059 B1 IE35059 B1 IE 35059B1
- Authority
- IE
- Ireland
- Prior art keywords
- fluoro
- derivatives
- trihydroxy
- etherified
- esterified
- Prior art date
Links
- PNSNPOQWOPPMQO-PZGHCZKVSA-N (8R,9S,10S,13S,14S,17S)-17-(2-fluoroethyl)-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,14,15,16-tetradecahydrocyclopenta[a]phenanthrene-3,16,17-triol Chemical class FCC[C@]1(C(C[C@@H]2[C@]1(C)CC[C@H]1[C@H]2CCC2CC(CC[C@]12C)O)O)O PNSNPOQWOPPMQO-PZGHCZKVSA-N 0.000 title 1
- 150000003431 steroids Chemical class 0.000 abstract 2
- JWYFRWLWDQYXBU-PUNTUCFWSA-N (8R,9S,10S,13S,14S,17S)-17-(2-fluoroethyl)-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,14,15,16-tetradecahydrocyclopenta[a]phenanthrene-16,17-diol Chemical class FCC[C@]1(C(C[C@@H]2[C@]1(C)CC[C@H]1[C@H]2CCC2CCCC[C@]12C)O)O JWYFRWLWDQYXBU-PUNTUCFWSA-N 0.000 abstract 1
- 239000004215 Carbon black (E152) Substances 0.000 abstract 1
- 125000001931 aliphatic group Chemical group 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 239000000969 carrier Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 230000003152 gestagenic effect Effects 0.000 abstract 1
- 229930195733 hydrocarbon Natural products 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 230000016087 ovulation Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH579370A CH552580A (de) | 1970-04-17 | 1970-04-17 | Verfahren zur herstellung neuer halogen-steroide. |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE35059L IE35059L (en) | 1971-10-17 |
| IE35059B1 true IE35059B1 (en) | 1975-10-29 |
Family
ID=4299399
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE458/71A IE35059B1 (en) | 1970-04-17 | 1971-04-14 | 21-fluoro-3,16,17-trihydroxy-pregnane compounds and their derivatives |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US3729466A (enExample) |
| AT (1) | AT311566B (enExample) |
| BE (1) | BE765833A (enExample) |
| CA (1) | CA932719A (enExample) |
| CH (1) | CH552580A (enExample) |
| CS (1) | CS153403B2 (enExample) |
| DE (1) | DE2118288A1 (enExample) |
| DK (1) | DK129041B (enExample) |
| ES (1) | ES390238A1 (enExample) |
| FI (1) | FI47482C (enExample) |
| FR (1) | FR2092053B1 (enExample) |
| GB (1) | GB1329207A (enExample) |
| HU (1) | HU164394B (enExample) |
| IE (1) | IE35059B1 (enExample) |
| IL (1) | IL36609A (enExample) |
| NL (1) | NL7105177A (enExample) |
| SE (1) | SE378825B (enExample) |
| SU (1) | SU404236A3 (enExample) |
| ZA (1) | ZA712353B (enExample) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE9203391U1 (de) * | 1991-12-18 | 1992-04-30 | Ernst Peiniger GmbH Unternehmen für Bautenschutz, 4300 Essen | Befestigungselement für Seitenschutzbretter auf einem Gerüst |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3386994A (en) * | 1965-05-05 | 1968-06-04 | Syntex Corp | Pregna-4, 6-diene-and 19-norpregna-4, 6-diene-3beta, 16, 17alpha-triol steroids, derivatives thereof, and processes for their preparation |
-
1970
- 1970-04-17 CH CH579370A patent/CH552580A/xx not_active IP Right Cessation
-
1971
- 1971-04-13 US US00133736A patent/US3729466A/en not_active Expired - Lifetime
- 1971-04-13 CA CA110123A patent/CA932719A/en not_active Expired
- 1971-04-13 IL IL36609A patent/IL36609A/xx unknown
- 1971-04-14 IE IE458/71A patent/IE35059B1/xx unknown
- 1971-04-14 ZA ZA712353A patent/ZA712353B/xx unknown
- 1971-04-15 DE DE19712118288 patent/DE2118288A1/de active Pending
- 1971-04-15 SU SU1647138A patent/SU404236A3/ru active
- 1971-04-15 SE SE7104886A patent/SE378825B/xx unknown
- 1971-04-15 ES ES390238A patent/ES390238A1/es not_active Expired
- 1971-04-16 HU HUCI1101A patent/HU164394B/hu unknown
- 1971-04-16 FI FI711049A patent/FI47482C/fi active
- 1971-04-16 FR FR7113540A patent/FR2092053B1/fr not_active Expired
- 1971-04-16 AT AT323071A patent/AT311566B/de not_active IP Right Cessation
- 1971-04-16 BE BE765833A patent/BE765833A/xx unknown
- 1971-04-16 DK DK183871AA patent/DK129041B/da unknown
- 1971-04-16 CS CS273971A patent/CS153403B2/cs unknown
- 1971-04-16 NL NL7105177A patent/NL7105177A/xx unknown
- 1971-04-19 GB GB979671*[A patent/GB1329207A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| GB1329207A (en) | 1973-09-05 |
| IL36609A0 (en) | 1971-06-23 |
| FI47482B (enExample) | 1973-08-31 |
| SU404236A3 (enExample) | 1973-10-26 |
| NL7105177A (enExample) | 1971-10-19 |
| FR2092053B1 (enExample) | 1974-08-23 |
| DK129041B (da) | 1974-08-12 |
| FI47482C (fi) | 1973-12-10 |
| US3729466A (en) | 1973-04-24 |
| FR2092053A1 (enExample) | 1972-01-21 |
| IE35059L (en) | 1971-10-17 |
| CS153403B2 (enExample) | 1974-02-25 |
| HU164394B (enExample) | 1974-02-28 |
| IL36609A (en) | 1975-02-10 |
| SE378825B (enExample) | 1975-09-15 |
| CA932719A (en) | 1973-08-28 |
| BE765833A (fr) | 1971-10-18 |
| ZA712353B (en) | 1971-12-29 |
| DE2118288A1 (de) | 1971-10-28 |
| ES390238A1 (es) | 1974-03-01 |
| AT311566B (de) | 1973-11-26 |
| CH552580A (de) | 1974-08-15 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CA1014686A (en) | Photopolymerizable compositions prepared from beta-hydroxy esters and polyitaconates | |
| GB1268230A (en) | Steroid glycosides and process for their manufacture | |
| GB1298218A (en) | NOVEL BEZ[e]INDENE AND PHENANTHRENE DERIVATIVES | |
| IE35059B1 (en) | 21-fluoro-3,16,17-trihydroxy-pregnane compounds and their derivatives | |
| GB1211219A (en) | 21-aldehydes of the pregnane series and derivatives thereof and process for their manufacture | |
| GB1409149A (en) | Quecetin derivatives and pharmaceutical uses thereof | |
| GB1148117A (en) | D-homosteroids and process for their manufacture | |
| IE34930L (en) | Fluocinolone - acetonide esters. | |
| GB1248418A (en) | 3-oxo-steroid-oximes and process for their manufacture | |
| GB1323775A (en) | Cardenolide-and bufadienolide-3-2,3-didesoxyglycosides and processes for their preparation | |
| IE37311B1 (en) | Pregnane-21-aldehydes and their derivatives and a process for the production thereof | |
| GB1296159A (enExample) | ||
| GB1363033A (en) | Derivatives of 22-fluoro-digoxins | |
| IE33379B1 (en) | New halogen-pregnadienes and process for their manufacture | |
| GB1239073A (enExample) | ||
| GB1262576A (en) | New halogen-pregnadienes and processes for the manufacture thereof | |
| IE34348B1 (en) | Esters of rho-biphenylylacetic acid | |
| GB1320302A (en) | 21-fluoro-16,17-dihydroxy-pregnane compounds and their derivatives | |
| ES367809A1 (es) | Procedimiento para la preparacion de 9beta, 10alfa,-este- roides. | |
| GB1230687A (enExample) | ||
| IE36110L (en) | Proscillaridin a acyl analogues. | |
| GB1271207A (en) | Preparation of 6-aminomethyl-steroids | |
| GB1333036A (en) | 3-oxo-a-nor-b-homo-oestra-5-10-6-dienes and a process for their manufacture | |
| GB1248500A (en) | 21-esters of triamcinolone and triamcinolone acetonide and a method of preparing them | |
| IE35071L (en) | Oestrone derivatives. |