IE33850B1 - Pyridoindole derivatives - Google Patents
Pyridoindole derivativesInfo
- Publication number
- IE33850B1 IE33850B1 IE1265/69A IE126569A IE33850B1 IE 33850 B1 IE33850 B1 IE 33850B1 IE 1265/69 A IE1265/69 A IE 1265/69A IE 126569 A IE126569 A IE 126569A IE 33850 B1 IE33850 B1 IE 33850B1
- Authority
- IE
- Ireland
- Prior art keywords
- compounds
- alkyl
- hoch
- ethylaniline
- alkoxycarbonyl
- Prior art date
Links
- IVCGJOSPVGENCT-UHFFFAOYSA-N 1h-pyrrolo[2,3-f]quinoline Chemical class N1=CC=CC2=C(NC=C3)C3=CC=C21 IVCGJOSPVGENCT-UHFFFAOYSA-N 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 3
- OJGMBLNIHDZDGS-UHFFFAOYSA-N N-Ethylaniline Chemical compound CCNC1=CC=CC=C1 OJGMBLNIHDZDGS-UHFFFAOYSA-N 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- -1 6 -substituted-4-pyridyl Chemical group 0.000 abstract 1
- OWZUVXOHWWCLNL-UHFFFAOYSA-N C1=CNC=C2C3=CC=CC=C3N=C21 Chemical class C1=CNC=C2C3=CC=CC=C3N=C21 OWZUVXOHWWCLNL-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 1
- 230000000202 analgesic effect Effects 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 150000004677 hydrates Chemical class 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- AJGLBACLTYFYRG-UHFFFAOYSA-N n-(2-pyridin-4-ylethyl)aniline Chemical compound C=1C=CC=CC=1NCCC1=CC=NC=C1 AJGLBACLTYFYRG-UHFFFAOYSA-N 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
- 239000007858 starting material Substances 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/42—Radicals substituted by singly-bound nitrogen atoms having hetero atoms attached to the substituent nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/38—Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
- Paper (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IE1332/71A IE33851B1 (en) | 1968-09-10 | 1969-09-09 | Novel pyridine derivatives |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US75871168A | 1968-09-10 | 1968-09-10 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE33850L IE33850L (en) | 1970-03-10 |
| IE33850B1 true IE33850B1 (en) | 1974-11-27 |
Family
ID=25052780
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE1265/69A IE33850B1 (en) | 1968-09-10 | 1969-09-09 | Pyridoindole derivatives |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US3502688A (cg-RX-API-DMAC7.html) |
| JP (1) | JPS5017480B1 (cg-RX-API-DMAC7.html) |
| AT (1) | AT286290B (cg-RX-API-DMAC7.html) |
| BE (1) | BE738580A (cg-RX-API-DMAC7.html) |
| BR (1) | BR6912232D0 (cg-RX-API-DMAC7.html) |
| CA (1) | CA967966A (cg-RX-API-DMAC7.html) |
| CH (1) | CH515255A (cg-RX-API-DMAC7.html) |
| DE (1) | DE1945821A1 (cg-RX-API-DMAC7.html) |
| DK (1) | DK125249B (cg-RX-API-DMAC7.html) |
| ES (2) | ES371324A1 (cg-RX-API-DMAC7.html) |
| FI (1) | FI49516C (cg-RX-API-DMAC7.html) |
| FR (1) | FR2017712B1 (cg-RX-API-DMAC7.html) |
| GB (2) | GB1253743A (cg-RX-API-DMAC7.html) |
| IE (1) | IE33850B1 (cg-RX-API-DMAC7.html) |
| IL (2) | IL39729A (cg-RX-API-DMAC7.html) |
| NL (1) | NL6913767A (cg-RX-API-DMAC7.html) |
| NO (1) | NO125489B (cg-RX-API-DMAC7.html) |
| SE (1) | SE365518B (cg-RX-API-DMAC7.html) |
| YU (1) | YU231769A (cg-RX-API-DMAC7.html) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS491567A (cg-RX-API-DMAC7.html) * | 1972-05-08 | 1974-01-08 | ||
| US4486593A (en) * | 1983-01-19 | 1984-12-04 | The Upjohn Company | 2-,3-, or 4-Pyridinylmethylamino arylic acids as thromboxane A2 synthetase and 5-lipoxygenase inhibitors |
| US4636563A (en) * | 1985-09-16 | 1987-01-13 | American Home Products Corporation | Antipsychotic γ-carbolines |
| US4672117A (en) * | 1985-09-16 | 1987-06-09 | American Home Products Corporation | Antipsychotic gamma-carbolines |
| US4754038A (en) * | 1987-02-26 | 1988-06-28 | American Home Products Corporation | Carboline histamine H1 antagonists |
| CA2683453C (en) * | 2007-04-05 | 2013-06-11 | Alla Chem, Llc | Substituted 2,3,4,5-tetrahydro-1h-pyrido[4,3-.beta.]indoles, methods for the production and use thereof |
| EP2194980A4 (en) * | 2007-09-20 | 2012-01-18 | D2E Llc | PYRIDO FLUORINE DERIVATIVES [4,3-B] HYDROGENATED INDOLES HAVING NEUROPROTECTIVE AND COGNITIVE PROPERTIES, PREPARATION METHOD AND USE |
| RU2007139634A (ru) | 2007-10-25 | 2009-04-27 | Сергей Олегович Бачурин (RU) | Новые тиазол-, триазол- или оксадиазол-содержащие тетрациклические соединения |
| WO2009082268A2 (ru) | 2007-12-21 | 2009-07-02 | Alla Chem, Llc | ЛИГАНДЫ α-АДРЕНОЦЕПТОРОВ, ДОПАМИНОВЫХ, ГИСТАМИНОВЫХ, ИМИДАЗОЛИНОВЫХ И СЕРОТОНИНОВЫХ РЕЦЕПТОРОВ И ИХ ПРИМЕНЕНИЕ |
| CA2760541A1 (en) * | 2009-04-29 | 2010-11-04 | Medivation Technologies, Inc. | Pyrido[4,3-b] indoles and methods of use |
| US8741919B2 (en) | 2009-04-29 | 2014-06-03 | Medivation Technologies, Inc. | Pyrido[4,3-B]indoles and methods of use |
| JP2014505737A (ja) | 2011-02-18 | 2014-03-06 | メディベイション テクノロジーズ， インコーポレイテッド | 糖尿病を処置する化合物および方法 |
-
1968
- 1968-09-10 US US758711A patent/US3502688A/en not_active Expired - Lifetime
-
1969
- 1969-08-22 CH CH1276869A patent/CH515255A/de not_active IP Right Cessation
- 1969-08-25 IL IL39729A patent/IL39729A/en unknown
- 1969-08-25 IL IL32889A patent/IL32889A/en unknown
- 1969-08-26 SE SE11817/69A patent/SE365518B/xx unknown
- 1969-08-29 CA CA060,756A patent/CA967966A/en not_active Expired
- 1969-09-03 DK DK472469AA patent/DK125249B/da unknown
- 1969-09-04 FI FI692560A patent/FI49516C/fi active
- 1969-09-08 BR BR212232/69A patent/BR6912232D0/pt unknown
- 1969-09-08 BE BE738580D patent/BE738580A/xx unknown
- 1969-09-08 FR FR696930458A patent/FR2017712B1/fr not_active Expired
- 1969-09-09 ES ES371324A patent/ES371324A1/es not_active Expired
- 1969-09-09 NO NO3601/69A patent/NO125489B/no unknown
- 1969-09-09 IE IE1265/69A patent/IE33850B1/xx unknown
- 1969-09-09 AT AT855069A patent/AT286290B/de not_active IP Right Cessation
- 1969-09-09 ES ES371323A patent/ES371323A1/es not_active Expired
- 1969-09-10 JP JP44071905A patent/JPS5017480B1/ja active Pending
- 1969-09-10 DE DE19691945821 patent/DE1945821A1/de active Pending
- 1969-09-10 YU YU02317/69A patent/YU231769A/xx unknown
- 1969-09-10 NL NL6913767A patent/NL6913767A/xx not_active Application Discontinuation
- 1969-09-10 GB GB6001/71A patent/GB1253743A/en not_active Expired
- 1969-09-10 GB GB44587/69A patent/GB1253742A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| GB1253743A (en) | 1971-11-17 |
| NL6913767A (cg-RX-API-DMAC7.html) | 1970-03-12 |
| NO125489B (cg-RX-API-DMAC7.html) | 1972-09-18 |
| GB1253742A (en) | 1971-11-17 |
| FI49516B (cg-RX-API-DMAC7.html) | 1975-04-01 |
| DE1945821A1 (de) | 1970-03-19 |
| CA967966A (en) | 1975-05-20 |
| ES371324A1 (es) | 1971-10-16 |
| BR6912232D0 (pt) | 1973-05-10 |
| JPS5017480B1 (cg-RX-API-DMAC7.html) | 1975-06-20 |
| DK125249B (da) | 1973-01-22 |
| US3502688A (en) | 1970-03-24 |
| IE33850L (en) | 1970-03-10 |
| ES371323A1 (es) | 1972-01-16 |
| FI49516C (fi) | 1975-07-10 |
| FR2017712B1 (cg-RX-API-DMAC7.html) | 1973-01-12 |
| IL39729A (en) | 1973-03-30 |
| YU231769A (en) | 1978-06-30 |
| FR2017712A1 (cg-RX-API-DMAC7.html) | 1970-05-22 |
| SE365518B (cg-RX-API-DMAC7.html) | 1974-03-25 |
| CH515255A (de) | 1971-11-15 |
| AT286290B (de) | 1970-12-10 |
| IL32889A (en) | 1973-03-30 |
| BE738580A (cg-RX-API-DMAC7.html) | 1970-03-09 |
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