IE33149L - Carbamates; hydorchloric acid secretion inhibition - Google Patents

Carbamates; hydorchloric acid secretion inhibition

Info

Publication number
IE33149L
IE33149L IE78169A IE78169A IE33149L IE 33149 L IE33149 L IE 33149L IE 78169 A IE78169 A IE 78169A IE 78169 A IE78169 A IE 78169A IE 33149 L IE33149 L IE 33149L
Authority
IE
Ireland
Prior art keywords
alkenyl
alkyl
acid secretion
alkoxyalkyl
radical
Prior art date
Application number
IE78169A
Other versions
IE33149B1 (en
Original Assignee
Haessle Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Haessle Ab filed Critical Haessle Ab
Publication of IE33149L publication Critical patent/IE33149L/en
Publication of IE33149B1 publication Critical patent/IE33149B1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/27—Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Emergency Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

1279412 Medicines comprising carbamates HASSLE AB 9 June 1969 [11 June 1968] 27787/68 Heading A5B [Also in Division C2] Pharmaceutical compositions for decreasing gastric hydrochloric acid secretion in mammals comprise a carbamate of formula I: (in which R<SP>1</SP> is C 1-6 alkyl, C 2-6 alkenyl, C 3-6 cycloalkyl, C 3-6 cycloalkenyl, C 2-8 alkoxyalkyl, or a radical of formula II: wherein A is C 1-4 alkylene, C 1-4 alkyleneoxy linked to the phenyl nucleus via the oxygen atom, or C 2-8 alkyleneoxyalkylene linked to the phenyl nucleus via a carbon atom, and each of R<SP>4</SP> and R<SP>5</SP> is H, OH, C 1-3 alkyl, C 2-3 alkenyl, C 1-3 alkoxy, C 2-3 alkenoxy, C 1-4 hydroxyalkyl, F, Cl, Br, NO 2 , CHO or NH 2 ; and R<SP>2</SP> is H, C 1-4 alkyl, C 2-4 alkenyl, C 3-6 cycloalkyl, C 3-6 cycloalkenyl, C 2-8 alkoxyalkyl, C 3-9 alkoxyalkoxyalkyl, or a radical -COR<SP>3</SP> wherein R<SP>3</SP> is C 1-4 alkyl, C 2-4 alkenyl, C 1-4 alkoxy, C 2-4 alkeneoxy, C 2-8 alkoxyalkoxy, C 3-9 alkoxyalkoxyalkyl, C 2-8 alkoxyalkyl, or a radical of formula III: wherein B is a valency bond or C 1-4 alkyleneoxy linked to the phenyl nucleus via a carbon atom) together with an anticholinergic compound. A list of specific anticholinergics is given. Compounds I can also be used alone for decreasing gastric hydrochloric acid secretion in mammals. [GB1279412A]
IE78169A 1968-06-11 1969-06-09 Gastric hydrochloric acid secretion inhibitor,process for the manufacture of such compounds,pharmaceutical composition and a method for the inhibition of gastric hydrochloric acid secretion IE33149B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB2778768A GB1279412A (en) 1968-06-11 1968-06-11 Gastric hydrochloric acid secretion inhibitor, process for the manufacture of such compounds, pharmaceutical composition and a method for the inhibition of gastric hydrochloric acid secretion

Publications (2)

Publication Number Publication Date
IE33149L true IE33149L (en) 1969-12-11
IE33149B1 IE33149B1 (en) 1974-04-03

Family

ID=10265313

Family Applications (1)

Application Number Title Priority Date Filing Date
IE78169A IE33149B1 (en) 1968-06-11 1969-06-09 Gastric hydrochloric acid secretion inhibitor,process for the manufacture of such compounds,pharmaceutical composition and a method for the inhibition of gastric hydrochloric acid secretion

Country Status (11)

Country Link
AT (6) AT293430B (en)
BE (1) BE734033A (en)
BR (1) BR6909672D0 (en)
CH (2) CH525193A (en)
DE (1) DE1929416A1 (en)
DK (1) DK126035B (en)
ES (3) ES368207A1 (en)
FR (2) FR2010650B1 (en)
GB (1) GB1279412A (en)
IE (1) IE33149B1 (en)
NL (1) NL6908843A (en)

Also Published As

Publication number Publication date
CH539021A (en) 1973-08-31
DK126035B (en) 1973-06-04
AT298667B (en) 1972-05-25
AT293428B (en) 1971-10-11
NL6908843A (en) 1969-12-15
ES388702A1 (en) 1973-05-16
CH525193A (en) 1972-07-15
AT293430B (en) 1971-10-11
FR2010650A1 (en) 1970-02-20
IE33149B1 (en) 1974-04-03
AT294849B (en) 1971-12-10
ES388703A1 (en) 1974-02-16
ES368207A1 (en) 1972-04-16
DE1929416A1 (en) 1970-07-16
AT292012B (en) 1971-08-10
FR2010650B1 (en) 1975-01-10
BR6909672D0 (en) 1973-03-13
GB1279412A (en) 1972-06-28
AT293429B (en) 1971-10-11
BE734033A (en) 1969-11-17
FR2140246A1 (en) 1973-01-12

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