HUT71402A - Use of terfenadine derivatives as antihistaminics in a hepatically impaired patient - Google Patents

Use of terfenadine derivatives as antihistaminics in a hepatically impaired patient

Info

Publication number
HUT71402A
HUT71402A HU9403234A HU9403234A HUT71402A HU T71402 A HUT71402 A HU T71402A HU 9403234 A HU9403234 A HU 9403234A HU 9403234 A HU9403234 A HU 9403234A HU T71402 A HUT71402 A HU T71402A
Authority
HU
Hungary
Prior art keywords
hydrogen
antihistaminics
impaired patient
hepatically impaired
patient
Prior art date
Application number
HU9403234A
Other languages
English (en)
Other versions
HU223774B1 (hu
Inventor
James K Woodward
Richard R Okerholm
Mark G Eller
Bruce E Mcnutt
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27128589&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HUT71402(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Publication of HUT71402A publication Critical patent/HUT71402A/hu
Publication of HU223774B1 publication Critical patent/HU223774B1/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
HU9403234A 1992-05-11 1993-04-06 Terfenadinszármazékok alkalmazása antihisztamin hatású gyógyszerkészítmények előállítására HU223774B1 (hu)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US88080192A 1992-05-11 1992-05-11
US92289092A 1992-07-31 1992-07-31
PCT/US1993/003151 WO1993023047A1 (en) 1992-05-11 1993-04-06 Use of terfenadine derivatives as antihistaminics in a hepatically impaired patient

Publications (2)

Publication Number Publication Date
HUT71402A true HUT71402A (en) 1995-11-28
HU223774B1 HU223774B1 (hu) 2005-01-28

Family

ID=27128589

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9403234A HU223774B1 (hu) 1992-05-11 1993-04-06 Terfenadinszármazékok alkalmazása antihisztamin hatású gyógyszerkészítmények előállítására

Country Status (16)

Country Link
US (7) US6037353A (hu)
EP (1) EP0639976B1 (hu)
JP (1) JPH07506828A (hu)
KR (1) KR950701525A (hu)
AT (1) ATE194913T1 (hu)
AU (1) AU679910B2 (hu)
CA (1) CA2134211C (hu)
CL (1) CL2004000304A1 (hu)
DE (1) DE69320952T2 (hu)
DK (1) DK0639976T3 (hu)
ES (1) ES2121084T3 (hu)
HU (1) HU223774B1 (hu)
MX (1) MX9302704A (hu)
NO (1) NO307688B1 (hu)
NZ (1) NZ251834A (hu)
WO (1) WO1993023047A1 (hu)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993023047A1 (en) * 1992-05-11 1993-11-25 Merrell Dow Pharmaceuticals Inc. Use of terfenadine derivatives as antihistaminics in a hepatically impaired patient
JP3041954B2 (ja) * 1992-08-03 2000-05-15 セプラコア インコーポレーテッド アレルギー疾患治療用のテルフェナジン代謝物及びその光学的に純粋な異性体
IT1271417B (it) * 1993-10-15 1997-05-28 Erregierre Ind Chim Composti ad attivita' antiistaminica procedimento per la loro preperazione e composizioni farmaceutiche che li contengono.
WO1995010278A1 (en) * 1993-10-15 1995-04-20 Hoechst Marion Roussel, Inc. Treatment of allergic disorders with terfenadine carboxylate
CN1148849A (zh) * 1994-05-18 1997-04-30 赫彻斯特马里恩鲁斯公司 抗组胺哌啶衍生物，其多晶形物和假同晶物的无水和水合物形式的制备方法
US20030045722A1 (en) * 1994-05-18 2003-03-06 Henton Daniel R. Processes for preparing anhydrous and hydrate forms of antihistaminic piperidine derivatives, polymorphs and pseudomorphs thereof
JP4105762B2 (ja) * 1995-02-28 2008-06-25 アベンティス・ファーマスーティカルズ・インコーポレイテツド ピペリジノアルカノール化合物のための医薬組成物
ES2192781T3 (es) * 1997-08-26 2003-10-16 Aventis Pharma Inc Composicion farmaceutica para combinacion de piperidinoalcanol y un descongestivo.
US6194431B1 (en) 1998-04-14 2001-02-27 Paul D. Rubin Methods and compositions using terfenadine metabolites in combination with leukotriene inhibitors
US20030021849A1 (en) * 2001-04-09 2003-01-30 Ben-Zion Dolitzky Polymorphs of fexofenadine hydrochloride
MXPA03009259A (es) * 2001-04-09 2004-06-03 Teva Pharma Polimorfos de clorhidrato de fexofenadina.
EP2316469A1 (en) 2002-02-22 2011-05-04 Shire LLC Delivery system and methods for protecting and administering dextroamphetamine
EP1474392A1 (en) * 2002-06-10 2004-11-10 Teva Pharmaceutical Industries Ltd. Polymorphic form xvi of fexofenadine hydrochloride
EP1393728A1 (en) * 2002-08-30 2004-03-03 Vrije Universiteit Inverse agonists acting at virus-encoded G protein-coupled receptors
US20050065183A1 (en) * 2003-07-31 2005-03-24 Indranil Nandi Fexofenadine composition and process for preparing
KR20070007196A (ko) * 2004-04-26 2007-01-12 테바 파마슈티컬 인더스트리즈 리미티드 펙소페나딘 히드로클로라이드의 결정형 및 이의 제조 방법
WO2006037042A1 (en) * 2004-09-28 2006-04-06 Teva Pharmaceutical Industries Ltd. Fexofenadine crystal form and processes for its preparation thereof
US20090076080A1 (en) * 2007-09-19 2009-03-19 Protia, Llc Deuterium-enriched fexofenadine
AU2009251743A1 (en) * 2008-05-30 2009-12-03 Fairfield Clinical Trials, Llc Method and composition for skin inflammation and discoloration

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4285958A (en) * 1979-04-10 1981-08-25 Richardson-Merrell Inc. 1-Piperidine-alkylene ketones, pharmaceutical compositions thereof and method of use thereof
US4254129A (en) * 1979-04-10 1981-03-03 Richardson-Merrell Inc. Piperidine derivatives
AR240018A1 (es) * 1987-10-07 1990-01-31 Merrell Pharma Inc Procedimiento para preparar una composicion que comprende derivados de piperidinoalcanol.
US4929605A (en) * 1987-10-07 1990-05-29 Merrell Dow Pharmaceuticals Inc. Pharmaceutical composition for piperidinoalkanol derivatives
WO1993023047A1 (en) * 1992-05-11 1993-11-25 Merrell Dow Pharmaceuticals Inc. Use of terfenadine derivatives as antihistaminics in a hepatically impaired patient
JP3041954B2 (ja) * 1992-08-03 2000-05-15 セプラコア インコーポレーテッド アレルギー疾患治療用のテルフェナジン代謝物及びその光学的に純粋な異性体

Also Published As

Publication number Publication date
WO1993023047A1 (en) 1993-11-25
US20030130315A1 (en) 2003-07-10
CA2134211A1 (en) 1993-11-25
DE69320952D1 (de) 1998-10-15
NO307688B1 (no) 2000-05-15
ATE194913T1 (de) 2000-08-15
MX9302704A (es) 1994-06-30
CL2004000304A1 (es) 2005-05-27
US6399632B1 (en) 2002-06-04
AU679910B2 (en) 1997-07-17
NO944287L (no) 1994-11-10
CA2134211C (en) 1999-06-29
US20030055083A1 (en) 2003-03-20
JPH07506828A (ja) 1995-07-27
NO944287D0 (no) 1994-11-10
ES2121084T3 (es) 2002-02-16
US6037353A (en) 2000-03-14
DE69320952T2 (de) 1999-05-27
AU3973493A (en) 1993-12-13
US20060205782A1 (en) 2006-09-14
HU223774B1 (hu) 2005-01-28
US20100168166A1 (en) 2010-07-01
KR950701525A (ko) 1995-04-28
NZ251834A (en) 1997-07-27
US6187791B1 (en) 2001-02-13
EP0639976B1 (en) 2000-07-26
DK0639976T3 (da) 1999-02-15
EP0639976A1 (en) 1995-03-01

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Legal Events

Date Code Title Description
HFG4 Patent granted, date of granting

Effective date: 20041207

GB9A Succession in title

Owner name: AVENTIS INC., US

Free format text: FORMER OWNER(S): MERRELL DOW PHARMACEUTICALS INC., US; MERRELL PHARMACEUTICALS INC., US

HC9A Change of name, address

Owner name: AVENTIS INC., US

Free format text: FORMER OWNER(S): MERRELL DOW PHARMACEUTICALS INC., US; MERRELL PHARMACEUTICALS INC., US

GB9A Succession in title

Owner name: AVENTISUB II INC., US

Free format text: FORMER OWNER(S): MERRELL DOW PHARMACEUTICALS INC., US; AVENTIS INC., US; MERRELL PHARMACEUTICALS INC., US