HUT62581A - Process for producing pipeidine derivatives and pharmaceutical compositions comprising such compounds
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Process for producing pipeidine derivatives and pharmaceutical compositions comprising such compounds
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Publication number
HUT62581A
HUT62581AHU922568AHU256892AHUT62581AHU T62581 AHUT62581 AHU T62581AHU 922568 AHU922568 AHU 922568AHU 256892 AHU256892 AHU 256892AHU T62581 AHUT62581 AHU T62581A
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Application filed by PfizerfiledCriticalPfizer
Priority to HU922568ApriorityCriticalpatent/HUT62581A/en
Publication of HU9202568D0publicationCriticalpatent/HU9202568D0/en
Publication of HUT62581ApublicationCriticalpatent/HUT62581A/en
3-piperidino-4-hydroxychroman derivs. of formula (I) and their salts are new, where A and B = H or A with B = -CH2CH2-. X = CH2 or O. X1 = H or OH. Z = H, F, Cl, Br or OH. Z1 = H, F, Cl, Br or 1-3C alkyl. n = O or 1; m = 0 or 1-6. When X = 0 (I) pref has cis stereochemistry. (I) are prepd. by hydride redn. of a suitable alpha-aminoketone, using e.g. NaBH4 in THF at -15 to 15 deg.C.
HU922568A1990-02-061990-02-06Process for producing pipeidine derivatives and pharmaceutical compositions comprising such compounds
HUT62581A
(en)