HUT55053A - Process for purifying antibioticum adriamycin-hydrochloride - Google Patents

Process for purifying antibioticum adriamycin-hydrochloride

Info

Publication number
HUT55053A
HUT55053A HU455889A HU455889A HUT55053A HU T55053 A HUT55053 A HU T55053A HU 455889 A HU455889 A HU 455889A HU 455889 A HU455889 A HU 455889A HU T55053 A HUT55053 A HU T55053A
Authority
HU
Hungary
Prior art keywords
adriamycin
soln
hydrochloride
ketone
antibioticum
Prior art date
Application number
HU455889A
Other languages
Hungarian (hu)
Other versions
HU204570B (en
Inventor
Jozsefne Marton
Janos Kuszmann
Lajos Toldy
Original Assignee
Gyogyszerkutato Intezet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gyogyszerkutato Intezet filed Critical Gyogyszerkutato Intezet
Priority to HU455889A priority Critical patent/HU204570B/en
Publication of HUT55053A publication Critical patent/HUT55053A/en
Publication of HU204570B publication Critical patent/HU204570B/en

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

Fermented or synthesised raw adriamycin-hydrochloride antibiotic is purified for pharmaceutical use, as follows. A mixt of an 1-4C aliphatic ketone and 1-5C aliphatic alcohol is added to raw adriamycin soln till incipient turbidity at 25-50deg.C. The soln is cooled to room temp and phased out tarry substances are removed. Pure adriamycin is pptd from the remaining soln by diluting it with a 1-4C aliphatic ketone. Opt. the isolated cpd. is resuspended in ketone, agitated, filtered and dri
HU455889A 1989-09-04 1989-09-04 Process for purifying adriamycin-hydrochloride HU204570B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
HU455889A HU204570B (en) 1989-09-04 1989-09-04 Process for purifying adriamycin-hydrochloride

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU455889A HU204570B (en) 1989-09-04 1989-09-04 Process for purifying adriamycin-hydrochloride

Publications (2)

Publication Number Publication Date
HUT55053A true HUT55053A (en) 1991-04-29
HU204570B HU204570B (en) 1992-01-28

Family

ID=10968314

Family Applications (1)

Application Number Title Priority Date Filing Date
HU455889A HU204570B (en) 1989-09-04 1989-09-04 Process for purifying adriamycin-hydrochloride

Country Status (1)

Country Link
HU (1) HU204570B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1188424C (en) * 1998-10-16 2005-02-09 美露香株式会社 Crystallization of doxorubicin hydrochloride

Also Published As

Publication number Publication date
HU204570B (en) 1992-01-28

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Legal Events

Date Code Title Description
HNF4 Restoration of lapsed final prot.
HMM4 Cancellation of final prot. due to non-payment of fee