HUT55053A - Process for purifying antibioticum adriamycin-hydrochloride - Google Patents
Process for purifying antibioticum adriamycin-hydrochlorideInfo
- Publication number
- HUT55053A HUT55053A HU455889A HU455889A HUT55053A HU T55053 A HUT55053 A HU T55053A HU 455889 A HU455889 A HU 455889A HU 455889 A HU455889 A HU 455889A HU T55053 A HUT55053 A HU T55053A
- Authority
- HU
- Hungary
- Prior art keywords
- adriamycin
- soln
- hydrochloride
- ketone
- antibioticum
- Prior art date
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Abstract
Fermented or synthesised raw adriamycin-hydrochloride antibiotic is purified for pharmaceutical use, as follows. A mixt of an 1-4C aliphatic ketone and 1-5C aliphatic alcohol is added to raw adriamycin soln till incipient turbidity at 25-50deg.C. The soln is cooled to room temp and phased out tarry substances are removed. Pure adriamycin is pptd from the remaining soln by diluting it with a 1-4C aliphatic ketone. Opt. the isolated cpd. is resuspended in ketone, agitated, filtered and dri
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HU455889A HU204570B (en) | 1989-09-04 | 1989-09-04 | Process for purifying adriamycin-hydrochloride |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HU455889A HU204570B (en) | 1989-09-04 | 1989-09-04 | Process for purifying adriamycin-hydrochloride |
Publications (2)
Publication Number | Publication Date |
---|---|
HUT55053A true HUT55053A (en) | 1991-04-29 |
HU204570B HU204570B (en) | 1992-01-28 |
Family
ID=10968314
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU455889A HU204570B (en) | 1989-09-04 | 1989-09-04 | Process for purifying adriamycin-hydrochloride |
Country Status (1)
Country | Link |
---|---|
HU (1) | HU204570B (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1188424C (en) | 1998-10-16 | 2005-02-09 | 美露香株式会社 | Crystallization of doxorubicin hydrochloride |
-
1989
- 1989-09-04 HU HU455889A patent/HU204570B/en not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
HU204570B (en) | 1992-01-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
HNF4 | Restoration of lapsed final prot. | ||
HMM4 | Cancellation of final prot. due to non-payment of fee |