HUT55053A - Process for purifying antibioticum adriamycin-hydrochloride
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Process for purifying antibioticum adriamycin-hydrochloride
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Publication number
HUT55053A
HUT55053AHU455889AHU455889AHUT55053AHU T55053 AHUT55053 AHU T55053AHU 455889 AHU455889 AHU 455889AHU 455889 AHU455889 AHU 455889AHU T55053 AHUT55053 AHU T55053A
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Application filed by Gyogyszerkutato IntezetfiledCriticalGyogyszerkutato Intezet
Priority to HU455889ApriorityCriticalpatent/HU204570B/en
Publication of HUT55053ApublicationCriticalpatent/HUT55053A/en
Publication of HU204570BpublicationCriticalpatent/HU204570B/en
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Saccharide Compounds
(AREA)
Abstract
Fermented or synthesised raw adriamycin-hydrochloride antibiotic is purified for pharmaceutical use, as follows. A mixt of an 1-4C aliphatic ketone and 1-5C aliphatic alcohol is added to raw adriamycin soln till incipient turbidity at 25-50deg.C. The soln is cooled to room temp and phased out tarry substances are removed. Pure adriamycin is pptd from the remaining soln by diluting it with a 1-4C aliphatic ketone. Opt. the isolated cpd. is resuspended in ketone, agitated, filtered and dri
HU455889A1989-09-041989-09-04Process for purifying adriamycin-hydrochloride
HU204570B
(en)