HUT51616A - Process for producing 5-substituted-2'-desoxy-uridines
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Process for producing 5-substituted-2'-desoxy-uridines
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Publication number
HUT51616A
HUT51616AHU594988AHU594988AHUT51616AHU T51616 AHUT51616 AHU T51616AHU 594988 AHU594988 AHU 594988AHU 594988 AHU594988 AHU 594988AHU T51616 AHUT51616 AHU T51616A
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Priority to HU594988ApriorityCriticalpatent/HU204840B/en
Publication of HUT51616ApublicationCriticalpatent/HUT51616A/en
Publication of HU204840BpublicationCriticalpatent/HU204840B/en
5-substd-2'-desoxyy-uridines of formula (I) are prepd from 5-substd uridines and 2-acetoxy-benzoyl-chlorides or bromides in a medium of acetic acid and with recirculation of hydrogen halides formed. Resulting cpd (II) is reductively dehalogenated by tri:butyltinhydride to yield 5-substd-desoxy',5'-di:acetoxy -2'--uridine which is de-acetylated. In these formulae R represents a halogen substd 1-8C alkyl or opt halogen substd 2-8C alkenyl gps while X is a chlorine or bromine atom. - (pp Dwg.No.)
HU594988A1988-11-181988-11-18Process for producing 5-disubstituted-2'-deoxyuridines
HU204840B
(en)