HUT44032A - Process for production of new derivatives of pirimido /5,4-bis/1,4/ oxasen - Google Patents
Process for production of new derivatives of pirimido /5,4-bis/1,4/ oxasenInfo
- Publication number
- HUT44032A HUT44032A HU855042A HU504285A HUT44032A HU T44032 A HUT44032 A HU T44032A HU 855042 A HU855042 A HU 855042A HU 504285 A HU504285 A HU 504285A HU T44032 A HUT44032 A HU T44032A
- Authority
- HU
- Hungary
- Prior art keywords
- group
- stands
- hydrogen
- alkyl
- alkyl group
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Indole Compounds (AREA)
Priority Applications (22)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HU855042A HU195822B (en) | 1985-12-30 | 1985-12-30 | Process for producing new pyrimido/5,4-b//1,h/oxazine derivatives |
NZ218795A NZ218795A (hu) | 1985-12-30 | 1986-12-23 | |
DK630186A DK630186A (da) | 1985-12-30 | 1986-12-29 | Pyrimido(5,4-b)(1,4)oxazinderivater, tautomer, tautomerblandinger og syreadditionssalte deraf, deres fremstilling og anvendelse som laegemidler |
CS8610262A CS268822B2 (en) | 1985-12-30 | 1986-12-30 | Method of pyrimido /5,4-/(1,4/-oxazine derivatives preparation |
US06/947,700 US4748175A (en) | 1985-12-30 | 1986-12-30 | Pyrimido[5,4-B][1,4]oxazine derivatives and pharmaceutical compositions containing them |
AU67043/86A AU586380B2 (en) | 1985-12-30 | 1986-12-30 | Pyrimido ``5,4-b````1,4`` oxazine derivatives and pharmaceutical compositions containing them |
ES8603622A ES2003643A6 (es) | 1985-12-30 | 1986-12-30 | Procedimiento de preparacion de los nuevos derivados pirimido (5,4-b) (1,4) oxazinos, asi como sus tautomeros y mezclas tautomeras y sales de adicion acidas de estos compuestos |
GR862962A GR862962B (en) | 1985-12-30 | 1986-12-30 | Pyrimido (5,4-b) (1,4) oxazine derivatives preparation process |
IL81117A IL81117A (en) | 1985-12-30 | 1986-12-30 | 2-alkyl-6h-pyrimido-(5,4-b)(1,4)oxazin-7(8h)-ones,their preparation and pharmaceutical compositions containing them |
CA000526548A CA1287052C (en) | 1985-12-30 | 1986-12-30 | Pyrimido[5,4-b][1,4]oxazine derivatives, pharmaceutical compositions containing them and process for preparing same |
DE8686118122T DE3680893D1 (de) | 1985-12-30 | 1986-12-30 | Pyrimido(5,4-b)(1,4)oxazinderivate, verfahren zu ihrer herstellung und diese enthaltende arzneimittel sowie zwischenprodukte darstellende pyrimido(5,4-b)(1,4)oxazinderivate. |
EP86118122A EP0228094B1 (de) | 1985-12-30 | 1986-12-30 | Pyrimido[5,4-b][1,4]oxazinderivate, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel sowie Zwischenprodukte darstellende Pyrimido[5,4-b][1,4]oxazinderivate |
NO865347A NO170935C (no) | 1985-12-30 | 1986-12-30 | Analogifremgangsmaate for fremstilling av terapeutisk aktive pyrimido(5,4-b)(1,4)oxazinderivater |
SU864028913A SU1567122A3 (ru) | 1985-12-30 | 1986-12-30 | Способ получени производных пиримидо (5-4 @ )-(1,4)оксазина или их аддитивных солей с кислотами |
FI865344A FI82469C (fi) | 1985-12-30 | 1986-12-30 | Foerfarande foer framstaellning av nya terapeutiskt anvaendbara 2-metyl-4-substituerad amino-6,7-dihydro-8h -pyrimido/5,4-b//1,4/-oxazin-7-oner. |
CN86108914A CN1021734C (zh) | 1985-12-30 | 1986-12-30 | 制备嘧啶并[5,4-b][1,4]嗪衍生物的方法 |
YU227986A YU46039B (sh) | 1985-12-30 | 1986-12-30 | Postupak za dobivanje novih pirimido/5,4-b/1,4/oksazinskih derivata |
AT86118122T ATE66232T1 (de) | 1985-12-30 | 1986-12-30 | Pyrimido(5,4-b>(1,4>oxazinderivate, verfahren zu ihrer herstellung und diese enthaltende arzneimittel sowie zwischenprodukte darstellende pyrimido(5,4-b>(1,4>oxazinderivate. |
DD86298832A DD256701A5 (de) | 1985-12-30 | 1986-12-30 | Verfahren zur herstellung neuer pyrimido (5,4-b) (1,4)-oxozin-derivate |
JP62000083A JPS62228082A (ja) | 1985-12-30 | 1987-01-05 | ピリミド(5,4−b)(1,4)オキサジン誘導体およびこれを含む薬剤組成物ならびにその製造方法 |
CS103188A CS272784B2 (en) | 1985-12-30 | 1988-02-18 | Method of pyrimido (5,4-8) (1,4) oxazin derivatives preparation |
SU884355907A SU1567123A3 (ru) | 1985-12-30 | 1988-06-14 | Способ получени производных пиримидо[5,4- @ ] [1,4]оксазина или их кислотно-аддитивных солей |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HU855042A HU195822B (en) | 1985-12-30 | 1985-12-30 | Process for producing new pyrimido/5,4-b//1,h/oxazine derivatives |
Publications (2)
Publication Number | Publication Date |
---|---|
HUT44032A true HUT44032A (en) | 1988-01-28 |
HU195822B HU195822B (en) | 1988-07-28 |
Family
ID=10969567
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU855042A HU195822B (en) | 1985-12-30 | 1985-12-30 | Process for producing new pyrimido/5,4-b//1,h/oxazine derivatives |
Country Status (20)
Country | Link |
---|---|
US (1) | US4748175A (hu) |
EP (1) | EP0228094B1 (hu) |
JP (1) | JPS62228082A (hu) |
CN (1) | CN1021734C (hu) |
AT (1) | ATE66232T1 (hu) |
AU (1) | AU586380B2 (hu) |
CA (1) | CA1287052C (hu) |
CS (1) | CS268822B2 (hu) |
DD (1) | DD256701A5 (hu) |
DE (1) | DE3680893D1 (hu) |
DK (1) | DK630186A (hu) |
ES (1) | ES2003643A6 (hu) |
FI (1) | FI82469C (hu) |
GR (1) | GR862962B (hu) |
HU (1) | HU195822B (hu) |
IL (1) | IL81117A (hu) |
NO (1) | NO170935C (hu) |
NZ (1) | NZ218795A (hu) |
SU (2) | SU1567122A3 (hu) |
YU (1) | YU46039B (hu) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IE64917B1 (en) * | 1988-02-05 | 1995-09-20 | Riker Laboratories Inc | Triazolo[1,5-c]pyrimido[1,4]azines as bronchodilators |
GB2359551A (en) * | 2000-02-23 | 2001-08-29 | Astrazeneca Uk Ltd | Pharmaceutically active pyrimidine derivatives |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4215216A (en) * | 1979-04-18 | 1980-07-29 | American Home Products Corporation | 7,8-Dihydro-2,5,8-trisubstituted-7-oxo-pyrido[2,3-d]pyrimidine-6-carboxylic acid derivatives |
-
1985
- 1985-12-30 HU HU855042A patent/HU195822B/hu not_active IP Right Cessation
-
1986
- 1986-12-23 NZ NZ218795A patent/NZ218795A/xx unknown
- 1986-12-29 DK DK630186A patent/DK630186A/da not_active Application Discontinuation
- 1986-12-30 AT AT86118122T patent/ATE66232T1/de not_active IP Right Cessation
- 1986-12-30 DE DE8686118122T patent/DE3680893D1/de not_active Expired - Fee Related
- 1986-12-30 FI FI865344A patent/FI82469C/fi not_active IP Right Cessation
- 1986-12-30 US US06/947,700 patent/US4748175A/en not_active Expired - Fee Related
- 1986-12-30 GR GR862962A patent/GR862962B/el unknown
- 1986-12-30 DD DD86298832A patent/DD256701A5/de not_active IP Right Cessation
- 1986-12-30 CS CS8610262A patent/CS268822B2/cs unknown
- 1986-12-30 IL IL81117A patent/IL81117A/xx not_active IP Right Cessation
- 1986-12-30 SU SU864028913A patent/SU1567122A3/ru active
- 1986-12-30 YU YU227986A patent/YU46039B/sh unknown
- 1986-12-30 CA CA000526548A patent/CA1287052C/en not_active Expired - Lifetime
- 1986-12-30 ES ES8603622A patent/ES2003643A6/es not_active Expired
- 1986-12-30 CN CN86108914A patent/CN1021734C/zh not_active Expired - Fee Related
- 1986-12-30 NO NO865347A patent/NO170935C/no unknown
- 1986-12-30 AU AU67043/86A patent/AU586380B2/en not_active Ceased
- 1986-12-30 EP EP86118122A patent/EP0228094B1/de not_active Expired - Lifetime
-
1987
- 1987-01-05 JP JP62000083A patent/JPS62228082A/ja active Pending
-
1988
- 1988-06-14 SU SU884355907A patent/SU1567123A3/ru active
Also Published As
Publication number | Publication date |
---|---|
DE3680893D1 (de) | 1991-09-19 |
YU227986A (en) | 1988-02-29 |
EP0228094B1 (de) | 1991-08-14 |
CA1287052C (en) | 1991-07-30 |
FI865344A (fi) | 1987-07-01 |
IL81117A0 (en) | 1987-03-31 |
GR862962B (en) | 1987-05-05 |
CN1021734C (zh) | 1993-08-04 |
DK630186A (da) | 1987-07-01 |
YU46039B (sh) | 1992-12-21 |
EP0228094A2 (de) | 1987-07-08 |
HU195822B (en) | 1988-07-28 |
DD256701A5 (de) | 1988-05-18 |
IL81117A (en) | 1990-07-12 |
EP0228094A3 (en) | 1988-10-12 |
DK630186D0 (da) | 1986-12-29 |
FI865344A0 (fi) | 1986-12-30 |
ATE66232T1 (de) | 1991-08-15 |
FI82469C (fi) | 1991-03-11 |
SU1567122A3 (ru) | 1990-05-23 |
AU6704386A (en) | 1987-07-02 |
SU1567123A3 (ru) | 1990-05-23 |
NZ218795A (hu) | 1989-02-24 |
NO170935B (no) | 1992-09-21 |
ES2003643A6 (es) | 1988-11-01 |
JPS62228082A (ja) | 1987-10-06 |
FI82469B (fi) | 1990-11-30 |
CS268822B2 (en) | 1990-04-11 |
CN86108914A (zh) | 1987-09-30 |
NO865347L (no) | 1987-07-01 |
CS1026286A2 (en) | 1989-08-14 |
NO170935C (no) | 1992-12-30 |
US4748175A (en) | 1988-05-31 |
AU586380B2 (en) | 1989-07-06 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE3567870D1 (en) | Xanthine derivatives, processes for their preparation and pharmaceutical compositions containing them | |
HU900063D0 (en) | Process for preparation of new 2-amino-pyrimidinone-derivatives | |
IL90552A0 (en) | Condensed pyrazole 3-oxo-propanenitrile derivatives,their preparation and pharmaceutical compositions containing them | |
HU893127D0 (en) | Process for the preparation of novel spiro-(imidazolidino-naphtaline) derivatives and pharmaceutical compositions containing such compounds as active ingredient | |
PH25532A (en) | Novel n-(4-piperidinyl) bicyclic condensed 2-imidazolamine derivatives, pharm,aceutical composition containing said compound, method of use thereof | |
HUT44032A (en) | Process for production of new derivatives of pirimido /5,4-bis/1,4/ oxasen | |
IL81337A (en) | Heptanoyl-glu-asp-ala-amino acid immunostimulants,process for their preparation and pharmaceutical compositions containing them | |
DE69429753D1 (de) | Anitbiotisch wirksame Cephalosporine und Verfahren zu ihrer Herstellung | |
ES2006390A6 (es) | Procedimiento de preparacion de nuevos derivados de morfolina. | |
IL61911A (en) | 2,3-dihydro-imidazo(1,2-b)pyridazine derivatives,their preparation and pharmaceutical compositions containing them | |
PT81066A (en) | Arphamine derivatives a process for their preparation and the pharmaceutical compositions therewith | |
MX9703074A (es) | Inhibidores de sintesis de apoliproteina-b. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
HU90 | Patent valid on 900628 | ||
HMM4 | Cancellation of final prot. due to non-payment of fee |