HUT43556A - Process for preparing aminophenol derivatives and pharmaceutics comprising these compounds as active substance - Google Patents

Process for preparing aminophenol derivatives and pharmaceutics comprising these compounds as active substance

Info

Publication number
HUT43556A
HUT43556A HU86112A HU11286A HUT43556A HU T43556 A HUT43556 A HU T43556A HU 86112 A HU86112 A HU 86112A HU 11286 A HU11286 A HU 11286A HU T43556 A HUT43556 A HU T43556A
Authority
HU
Hungary
Prior art keywords
alkyl
nr3r4
alkoxy
pharmaceutics
compounds
Prior art date
Application number
HU86112A
Other languages
Hungarian (hu)
Other versions
HU206869B (en
Inventor
Ian F Skidmore
Harry Finch
Alan Naylor
Lawrence H Lunts
Ian B Campbell
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of HUT43556A publication Critical patent/HUT43556A/en
Publication of HU206869B publication Critical patent/HU206869B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C217/06—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted
    • C07C217/08—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to an acyclic carbon atom
    • C07C217/10—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to an acyclic carbon atom to an acyclic carbon atom of a hydrocarbon radical containing six-membered aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

2-Phenylalkoxyalkyl amino-1-(3-substd.-amino-4 -hydroxy phenyl)ethanol derivs. and analogues of formula (I) and their salts and solvates are new. Ar = Ph opt. substd. by halogen, 1-6C alkyl, 1-6C alkoxy, NO2, (CH2)qR, (CH2)rR10, O(CH2)tR11 or by a O(CH2)pO gp.; R = OH NR3R4, NR5COR6, NR5SO2R7, COR8, SR9, SOR9, SO2R9 or CN; q = 0-3; R3-R5 = H or 1-4C alkyl; or NR3R4 = 5- to 7-membered satd. heterocyclylic amino opt. contg. in the ring one or more O, S, NH or NMe; R6 = H, 1-4C alkyl, 1-4C alkoxy, Ph or NR3R4; R7 = 1-4C alkyl, Ph or NR3R4; R7 = 1-4C alkyl, Ph or NR3R4; R8 = OH, 1-4C alkoxy or NR3R4; R9 = H, 1-4C alkyl or Ph; R10 = 1-4C alkoxy; r = 1-3; R11 = OH or 1-4C alkoxy; t = 2 or 3; p = 1 or 2; R1, R2 = H Or 1-3C alkyl, provided that R1+R2 do not contain over 4C; X = 1-7C alkylene, 2-7C alkenylene or 2-7C alkynylene or 2-6C alkynylene, provided that X-Y contain 2-10C; Q = R12CO, R12NHCO, R12R13NSO2 or R14SO2; R12, R13 = H Or 1-3C alkyl; R14 = 1-4C alkyl.
HU86112A 1984-07-13 1986-01-10 Process for producing amino-phenol derivatives and pharmaceutical compositions containing them HU206869B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB848417897A GB8417897D0 (en) 1984-07-13 1984-07-13 Chemical compounds

Publications (2)

Publication Number Publication Date
HUT43556A true HUT43556A (en) 1987-11-30
HU206869B HU206869B (en) 1993-01-28

Family

ID=10563848

Family Applications (1)

Application Number Title Priority Date Filing Date
HU86112A HU206869B (en) 1984-07-13 1986-01-10 Process for producing amino-phenol derivatives and pharmaceutical compositions containing them

Country Status (5)

Country Link
JP (1) JPS6150950A (en)
KR (1) KR860001061A (en)
GB (1) GB8417897D0 (en)
HU (1) HU206869B (en)
ZA (2) ZA855297B (en)

Also Published As

Publication number Publication date
JPS6150950A (en) 1986-03-13
HU206869B (en) 1993-01-28
ZA855297B (en) 1986-04-30
KR860001061A (en) 1986-02-22
ZA86193B (en) 1987-04-29
GB8417897D0 (en) 1984-08-15

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Legal Events

Date Code Title Description
HMM4 Cancellation of final prot. due to non-payment of fee