HUT41717A - Process for preparing fluorin ated resorcine ethers
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Process for preparing fluorin ated resorcine ethers
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Publication number
HUT41717A
HUT41717AHU415985AHU415985AHUT41717AHU T41717 AHUT41717 AHU T41717AHU 415985 AHU415985 AHU 415985AHU 415985 AHU415985 AHU 415985AHU T41717 AHUT41717 AHU T41717A
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Application filed by Ciba Geigy AgfiledCriticalCiba Geigy Ag
Priority to HU415985ApriorityCriticalpatent/HUT41717A/en
Publication of HUT41717ApublicationCriticalpatent/HUT41717A/en
Organic Low-Molecular-Weight Compounds And Preparation Thereof
(AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Abstract
Resorcinol ethers of formula (I) and their salts are new; R1 = alkyl; R2 = fluoroalkyl; R3 = H, alkoxy, CF3 or halo; alk = alkylene or hydroxyalkylene, opt. substd. by one of R4, R5 and R7 = NHCO.R8, the others one R9 (in the case of R4 and R5) or R10 (in the case of R7); R6 = H, alkyl, CF3, halo,COOH (opt. as ester or amide), CN or alkanoyl; R8 = COOH (opt. as ester or amide) or 5-tetrazolyl; R9 = H, alkyl, alkoxy, halo or CF3; R10 = H, alkyl, alkoxy, halo, CF3, CN or COOH (opt. as ester or amide). All alkyl etc. are 'lower'. The intermediates of formula (XXXIII) and their salts are new; R1 = 1-4C alkyl; R2 = 1-3C fluoroalkyl wih 1-3F on the omega C atom; R3 and R7 = H; one of R4 and R5 = 1-4C alkyl and the other F, Cl or Br; R5 = oxaloamino or 5-tetrazolylcarbonylamino; alk = linear 2-5C alkylene or 3-7C hydroxyalkylene (OH not on alpha or omegae atoms). - About 30 cpds. e.g. N-((3-(3-(4-acetyl-3-hydroxy-2- (3,3,3-trifluoropropyl phenoxy)propoxy) -4-chloro-6-methylphenyl)) -1H-tetrazole -5-carboxamide (Ia) and the corresp,. 4-(bromo-cyano or fluor) cpds. are specifically claimed.
HU415985A1985-10-301985-10-30Process for preparing fluorin ated resorcine ethers
HUT41717A
(en)
Perfluoroalkyl-substituted benzoyl-guanidine, process for producing them, use of them as medicament or diagnosticum, and pharmaceutical composition containing them
Phenyl-substituted alkylcarboguanidides carrying perfluoroalkyl groups, a process for their preparation, their use as a medicament or a diagnostic agent, and medicament containing them