HUT37893A - Process for production of stabil watery insuline preparatives - Google Patents

Process for production of stabil watery insuline preparatives

Info

Publication number
HUT37893A
HUT37893A HU852203A HU220385A HUT37893A HU T37893 A HUT37893 A HU T37893A HU 852203 A HU852203 A HU 852203A HU 220385 A HU220385 A HU 220385A HU T37893 A HUT37893 A HU T37893A
Authority
HU
Hungary
Prior art keywords
plunger pipe
plate
damper
sealing plate
pipe
Prior art date
Application number
HU852203A
Other languages
English (en)
Other versions
HU200102B (en
Inventor
Ulrich Grau
Gerhard Ross
Dietrich Hiller
Horst P Neubauer
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19843443877 external-priority patent/DE3443877A1/de
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of HUT37893A publication Critical patent/HUT37893A/hu
Publication of HU200102B publication Critical patent/HU200102B/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/28—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Endocrinology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Luminescent Compositions (AREA)
  • Prostheses (AREA)
  • Steroid Compounds (AREA)
  • External Artificial Organs (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
HU852203A 1984-06-09 1985-06-04 Process for producing aquous insulin composition stabilized against mechanical force HU200102B (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE3421615 1984-06-09
DE3421613 1984-06-09
DE19843443877 DE3443877A1 (de) 1984-06-09 1984-12-01 Insulinzubereitungen, verfahren zu deren herstellung und deren verwendung

Publications (2)

Publication Number Publication Date
HUT37893A true HUT37893A (en) 1986-03-28
HU200102B HU200102B (en) 1990-04-28

Family

ID=27192050

Family Applications (1)

Application Number Title Priority Date Filing Date
HU852203A HU200102B (en) 1984-06-09 1985-06-04 Process for producing aquous insulin composition stabilized against mechanical force

Country Status (16)

Country Link
EP (1) EP0166971B1 (hu)
AT (1) ATE50502T1 (hu)
AU (1) AU575951B2 (hu)
CA (1) CA1258427A (hu)
DE (1) DE3576120D1 (hu)
DK (1) DK162255C (hu)
ES (1) ES8605679A1 (hu)
FI (1) FI80596C (hu)
GR (1) GR851393B (hu)
HU (1) HU200102B (hu)
IE (1) IE57998B1 (hu)
IL (1) IL75448A (hu)
NO (1) NO164277C (hu)
NZ (1) NZ212338A (hu)
PH (1) PH24118A (hu)
PT (1) PT80620B (hu)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ228285A (en) * 1988-03-11 1991-08-27 Teikoku Seiyaku Kk Pharmaceutical composition comprising a polypeptide and adapted for intravaginal administration
DE10114178A1 (de) 2001-03-23 2002-10-10 Aventis Pharma Gmbh Zinkfreie und zinkarme Insulinzubereitungen mit verbesserter Stabilität
DE10227232A1 (de) * 2002-06-18 2004-01-15 Aventis Pharma Deutschland Gmbh Saure Insulinzubereitungen mit verbesserter Stabilität
HUE037449T2 (hu) 2008-10-17 2018-08-28 Sanofi Aventis Deutschland Egy inzulin és egy GLP-1 agonista kombinációja
PE20121316A1 (es) 2009-11-13 2012-10-05 Sanofi Aventis Deutschland Composicion farmaceutica que comprende un agonista de glp-1 y metionina
RU2537239C2 (ru) 2009-11-13 2014-12-27 Санофи-Авентис Дойчланд Гмбх Фармацевтическая композиция, включающая агонист glp-1, инсулин и метионин
PT2611458T (pt) 2010-08-30 2016-12-16 Sanofi Aventis Deutschland Utilização de ave0010 para o fabrico de um medicamento para o tratamento da diabetes mellitus tipo 2
US9821032B2 (en) 2011-05-13 2017-11-21 Sanofi-Aventis Deutschland Gmbh Pharmaceutical combination for improving glycemic control as add-on therapy to basal insulin
TWI559929B (en) 2011-09-01 2016-12-01 Sanofi Aventis Deutschland Pharmaceutical composition for use in the treatment of a neurodegenerative disease
HUE042381T2 (hu) 2013-04-03 2019-06-28 Sanofi Sa Cukorbetegség kezelése hosszan ható inzulinkészítményekkel
CA2970200A1 (en) 2014-12-12 2016-06-16 Sanofi-Aventis Deutschland Gmbh Insulin glargine/lixisenatide fixed ratio formulation
TWI748945B (zh) 2015-03-13 2021-12-11 德商賽諾菲阿凡提斯德意志有限公司 第２型糖尿病病患治療
TW201705975A (zh) 2015-03-18 2017-02-16 賽諾菲阿凡提斯德意志有限公司 第２型糖尿病病患之治療

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2474729A (en) * 1945-01-03 1949-06-28 Rhone Poulenc Sa Insulin preparations
US2574889A (en) * 1947-10-06 1951-11-13 Leo Ab Methylated gelatin-insulin preparation
SU1011126A1 (ru) * 1981-07-14 1983-04-15 Всесоюзный научно-исследовательский и испытательный институт медицинской техники Средство дл лечени сахарного диабета
CA1176160A (en) * 1981-08-27 1984-10-16 Ronald E. Chance Human proinsulin pharmaceutical formulations
FI78616C (fi) * 1982-02-05 1989-09-11 Novo Industri As Foerfarande foer framstaellning av en foer infusionsaendamaol avsedd stabiliserad insulinloesning, som har en foerhoejd zinkhalt.
WO1985005036A1 (en) * 1984-04-30 1985-11-21 The Trustees Of Columbia University In The City Of Topical treatment of diabetes with insulin and penetrant enhancer applied to the skin and covered by a patch

Also Published As

Publication number Publication date
IE57998B1 (en) 1993-06-02
PT80620A (de) 1985-07-01
ATE50502T1 (de) 1990-03-15
AU4342485A (en) 1985-12-12
NZ212338A (en) 1989-02-24
FI852273A0 (fi) 1985-06-06
NO852314L (no) 1985-12-10
DK162255C (da) 1992-03-16
EP0166971A1 (de) 1986-01-08
DK254585A (da) 1985-12-10
FI80596C (fi) 1990-07-10
ES8605679A1 (es) 1986-01-16
PT80620B (pt) 1987-10-20
DK162255B (da) 1991-10-07
PH24118A (en) 1990-03-05
ES543972A0 (es) 1986-01-16
IL75448A (en) 1989-07-31
DK254585D0 (da) 1985-06-06
IE851431L (en) 1985-12-09
HU200102B (en) 1990-04-28
FI80596B (fi) 1990-03-30
CA1258427A (en) 1989-08-15
NO164277B (no) 1990-06-11
DE3576120D1 (de) 1990-04-05
NO164277C (no) 1990-09-19
AU575951B2 (en) 1988-08-11
GR851393B (en) 1985-11-25
IL75448A0 (en) 1985-10-31
FI852273L (fi) 1985-12-10
EP0166971B1 (de) 1990-02-28

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Legal Events

Date Code Title Description
HU90 Patent valid on 900628