HUT36109A - New pharmaceutical preparations containing valeptoriate-hydrine - Google Patents
New pharmaceutical preparations containing valeptoriate-hydrineInfo
- Publication number
- HUT36109A HUT36109A HU842912A HU291284A HUT36109A HU T36109 A HUT36109 A HU T36109A HU 842912 A HU842912 A HU 842912A HU 291284 A HU291284 A HU 291284A HU T36109 A HUT36109 A HU T36109A
- Authority
- HU
- Hungary
- Prior art keywords
- acid
- stands
- beta
- hydroxy
- carbon atoms
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/94—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Hydrogenated Pyridines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pyrane Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
1. Claims for the contracting States : BE, CH, DE, FR, GB, IT, LI, NL Use of polyacyloxycyclopenta(c)pyran compounds of the general formula I see diagramm : EP0133673,P15,F2 in which A stands for hydrogen and B stands for hydrogen or hydroxy or A and B together form a bond, of the radicals R1 to R3 one stands for isovaleroyl, another stands for acetyl and the third stands for the acyl radical of one of the following acids : isovaleric acid, beta-methylvaleric acid, alpha-isovaleroyloxyisovaleric acid, alpha-acetoxyisovaleric acid, beta-acetoxyisovaleric acid, beta-acetoxy-beta-methylvaleric acid or beta-hydroxyisovaleric acid, and X stands for halogen, cyano, thiocyano, azido or an acyloxy radical R4 COO, in which R4 is an alkyl group, optionally substituted with hydroxy, with 1 to 20 carbon atoms or an alkenyl group with 3-20 carbon atoms or a phenyl, phenylalkyl or phenylalkenyl group with up to 3 carbon atoms in the alkylene or alkenylene chain, which may be optionally substituted in the phenyl ring with halogen, trifluoromethyl, hydroxy, lower alkyl or lower alkoxy, for the production of pharmaceutical preparations for the treatment and prophylaxis of peptic ulcers and/or for the treatment of spasmodic motility disorders in the gastrointestinal tract in larger mammals and humans. 1. Claims for the contracting State : AT Use of polyacyloxycyclopenta(c)pyran compounds of the general formula I see diagramm : EP0133673,P18,F1 in which A stands for hydrogen and B stands for hydrogen or hydroxy or A and B together form a bond, of the radicals R1 to R3 one stands for isovaleroyl, another stands for acetyl and the third stands for the acyl radical of one of the following acids : isovaleric acid, beta-methylvaleric acid, alpha-isovaleroyloxyisovaleric acid, alpha-acetoxyisovaleric acid, beta-acetoxyisovaleric acid, beta-acetoxy-beta-methylvaleric acid or beta-hydroxyisovaleric acid, and X stands for halogen, cyano, thiocyano, azido or an acyloxy radical R4 COO, in which R4 is an alkyl group, optionally substituted with hydroxy, with 1 to 20 carbon atoms or an alkenyl group with 3-20 carbon atoms or a phenyl, phenylalkyl or phenylalkenyl group with up to 3 carbon atoms in the alkylene or alkenylene chain, which may be optionally substituted in the phenyl ring with halogen, trifluoromethyl, hydroxy, lower alkyl or lower alkoxy, for the production of pharmaceutical preparations for the treatment and prophylaxis of peptic ulcers and/or for the treatment of spasmodic motility disorders in the gastrointestinal tract in larger mammals and humans.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19833327811 DE3327811A1 (en) | 1983-08-02 | 1983-08-02 | NEW VALEPOTRIATHYDRINE-CONTAINING MEDICINAL PRODUCTS |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HUT36109A true HUT36109A (en) | 1985-08-28 |
| HU201044B HU201044B (en) | 1990-09-28 |
Family
ID=6205533
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU842912A HU201044B (en) | 1983-08-02 | 1984-07-30 | Process for production of medical compositions containing new valepotriate-hydrinel and for production of new velopotriate |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US4891384A (en) |
| EP (1) | EP0133673B1 (en) |
| JP (1) | JPS6054382A (en) |
| AT (1) | ATE27911T1 (en) |
| DE (2) | DE3327811A1 (en) |
| DK (1) | DK372884A (en) |
| HU (1) | HU201044B (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7815936B2 (en) * | 2001-10-30 | 2010-10-19 | Evonik Degussa Gmbh | Use of granular materials based on pyrogenically produced silicon dioxide in pharmaceutical compositions |
| EP1700824A1 (en) * | 2005-03-09 | 2006-09-13 | Degussa AG | Granules based on pyrogenically prepared silicon dioxide, method for their preparation and use thereof |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1191515B (en) * | 1963-01-26 | 1965-04-22 | Kali Chemie Ag | Process for obtaining sedative and spasmolytic esters from Radix valerianae |
| US3812154A (en) * | 1969-12-08 | 1974-05-21 | Kali Chemie Ag | Dioxatricyclodecanes |
| US3917651A (en) * | 1969-12-08 | 1975-11-04 | Kali Chemie Ag | Dioxatricyclodecanones |
| DE1961433C3 (en) * | 1969-12-08 | 1974-06-06 | Kali Chemie Ag | S-alkoxy ^ -hydroxy-S-methyl-lOmethylene-2,9-dioxatricyclo- (4,3, l, 0 to the power of 3, to the power of 7) -decane and 8-alkoxy-4-hydroxy-3,10-dimethyl- 2,9dioxatricyclo- (4,3,1,0 to the power of 3Jioch 7) -decane and process for their preparation |
| US3987037A (en) * | 1971-09-03 | 1976-10-19 | Minnesota Mining And Manufacturing Company | Chromophore-substituted vinyl-halomethyl-s-triazines |
| DE2230626B2 (en) * | 1972-06-22 | 1978-07-20 | Roland Dr. 7967 Bad Waldsee Schaette | Valerian preparation |
| DE2654709C3 (en) * | 1976-12-02 | 1987-07-09 | A. H. Robins Co. Inc., Richmond, Va. | Method for stabilizing valerian extract preparations |
| US4189323A (en) * | 1977-04-25 | 1980-02-19 | Hoechst Aktiengesellschaft | Radiation-sensitive copying composition |
| JPS5928328B2 (en) * | 1977-11-29 | 1984-07-12 | 富士写真フイルム株式会社 | Photopolymerizable composition |
| DE2849029A1 (en) * | 1978-11-11 | 1980-05-22 | Kali Chemie Pharma Gmbh | STABLE VALEPOTRIATE PREPARATIONS AND METHOD FOR THE PRODUCTION THEREOF |
| DE3026579A1 (en) * | 1980-07-14 | 1982-02-11 | Kali-Chemie Pharma Gmbh, 3000 Hannover | 2,9-DIOXATRICYCLO (4,3,1, O (UP ARROW) 3,7 (UP ARROW)) DECANE |
| DE3112737A1 (en) * | 1981-03-31 | 1982-10-07 | Gehrlicher Kg | Process for obtaining epoxide-free sedative agents from plants of the family Valerianaceae |
-
1983
- 1983-08-02 DE DE19833327811 patent/DE3327811A1/en not_active Withdrawn
-
1984
- 1984-07-27 DE DE8484108898T patent/DE3464330D1/en not_active Expired
- 1984-07-27 EP EP84108898A patent/EP0133673B1/en not_active Expired
- 1984-07-27 AT AT84108898T patent/ATE27911T1/en not_active IP Right Cessation
- 1984-07-30 HU HU842912A patent/HU201044B/en not_active IP Right Cessation
- 1984-08-01 DK DK372884A patent/DK372884A/en not_active Application Discontinuation
- 1984-08-02 JP JP59161642A patent/JPS6054382A/en active Granted
-
1988
- 1988-05-03 US US07/191,819 patent/US4891384A/en not_active Expired - Fee Related
-
1989
- 1989-10-18 US US07/423,249 patent/US4980487A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP0133673B1 (en) | 1987-06-24 |
| US4891384A (en) | 1990-01-02 |
| HU201044B (en) | 1990-09-28 |
| US4980487A (en) | 1990-12-25 |
| ATE27911T1 (en) | 1987-07-15 |
| DE3464330D1 (en) | 1987-07-30 |
| DE3327811A1 (en) | 1985-02-21 |
| JPH0528235B2 (en) | 1993-04-23 |
| JPS6054382A (en) | 1985-03-28 |
| DK372884A (en) | 1985-02-03 |
| DK372884D0 (en) | 1984-08-01 |
| EP0133673A1 (en) | 1985-03-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| HMM4 | Cancellation of final prot. due to non-payment of fee |