HUT34994A - Process for producing new steroide-17-spiro-lactones and corresponding salts of carboxylic acides - Google Patents

Process for producing new steroide-17-spiro-lactones and corresponding salts of carboxylic acides

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Publication number
HUT34994A
HUT34994A HU317583A HU317583A HUT34994A HU T34994 A HUT34994 A HU T34994A HU 317583 A HU317583 A HU 317583A HU 317583 A HU317583 A HU 317583A HU T34994 A HUT34994 A HU T34994A
Authority
HU
Hungary
Prior art keywords
carbons
formula
thio
hydrogen
lactones
Prior art date
Application number
HU317583A
Other languages
Hungarian (hu)
Other versions
HU190154B (en
Inventor
Saandor Soolyom
Lajos Toldy
Geezaanee Szilaagyi
Inge Schaefer
Balogh Maaria Nagynee
Original Assignee
Gyogyszerkutato Inteezet Kv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gyogyszerkutato Inteezet Kv filed Critical Gyogyszerkutato Inteezet Kv
Priority to HU317583A priority Critical patent/HU190154B/en
Publication of HUT34994A publication Critical patent/HUT34994A/en
Priority to SU864027297A priority patent/RU2027431C1/en
Publication of HU190154B publication Critical patent/HU190154B/en

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Abstract

Novel steroido-spiro-lactones of formula I and the salts obtd. by opening the lactone ring have anti-mineralo-corticoid properties. - In the formula Z means a gp. of formula II or III, M is an alkali-metal atom, R1 is hydrogen or methyl, R2 is alkyl with 1-3 carbons, X stands for methine, methylene or cyclo-propylidene, the dotted line between carbons no. 1 and 2 may mean an additional valency bond, A means a gp. of formula a, b or c, Y1 is hydrogen, hydroxyl, alkanoyl-oxy with 2-4 carbons, alkyl-thio with 1-3 carbons or alkanoyl-thio with 2-3 carbons, if Y1 is hydrogen the dotted line between carbons no. 3 and 4 is an additional valency bond. B means a gp. of formula d, e, f or g, Y2 is hydrogen, alkyl-thio with 1-3 carbons or alkanoyl-thio with 2-3 carbons, the dotted lines between carbons no. 5-6 or 6-7 may mean additional valency bonds D means a gp. of formula h, i or j, where the dotted line between carbons no. 15 and 16 may mean an additional valency bond, with the proviso, that at least one of carbons no. 2 and 16 carries a cyclo-propylidene gp., further that if X means cyclo-propylidene, than a gp. of formula c occupies A and there may be further double bonds between carbons no. 6-7 and 15-16, or these carbons may be linked by a methylene gp. next to the single bond.
HU317583A 1983-06-03 1983-09-13 Process for producing new steroide-17-spiro-lactones HU190154B (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
HU317583A HU190154B (en) 1983-09-13 1983-09-13 Process for producing new steroide-17-spiro-lactones
SU864027297A RU2027431C1 (en) 1983-06-03 1986-04-08 Agent for skin care

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU317583A HU190154B (en) 1983-09-13 1983-09-13 Process for producing new steroide-17-spiro-lactones

Publications (2)

Publication Number Publication Date
HUT34994A true HUT34994A (en) 1985-05-28
HU190154B HU190154B (en) 1986-08-28

Family

ID=10962947

Family Applications (1)

Application Number Title Priority Date Filing Date
HU317583A HU190154B (en) 1983-06-03 1983-09-13 Process for producing new steroide-17-spiro-lactones

Country Status (1)

Country Link
HU (1) HU190154B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009111574A2 (en) * 2008-03-05 2009-09-11 Evestra, Inc. BISMETHYLENE-17α CARBOLACTONES AND RELATED USES

Also Published As

Publication number Publication date
HU190154B (en) 1986-08-28

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