HUT34198A - Process for the production of 7,8,9,10-tetrahydrothieno/3,2-e/-pyrido/4,3-b/indoles and of therapeutic products containing such compounds - Google Patents
Process for the production of 7,8,9,10-tetrahydrothieno/3,2-e/-pyrido/4,3-b/indoles and of therapeutic products containing such compoundsInfo
- Publication number
- HUT34198A HUT34198A HU841260A HU126084A HUT34198A HU T34198 A HUT34198 A HU T34198A HU 841260 A HU841260 A HU 841260A HU 126084 A HU126084 A HU 126084A HU T34198 A HUT34198 A HU T34198A
- Authority
- HU
- Hungary
- Prior art keywords
- indoles
- tetrahydrothieno
- pyrido
- compounds
- production
- Prior art date
Links
- 150000002475 indoles Chemical class 0.000 title abstract 3
- 150000001875 compounds Chemical class 0.000 title 1
- 230000001225 therapeutic effect Effects 0.000 title 1
- SIKJAQJRHWYJAI-UHFFFAOYSA-N Indole Chemical compound C1=CC=C2NC=CC2=C1 SIKJAQJRHWYJAI-UHFFFAOYSA-N 0.000 abstract 2
- 239000000935 antidepressant agent Substances 0.000 abstract 2
- 229940005513 antidepressants Drugs 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- XBBKXEIFGVVLNV-UHFFFAOYSA-N 7.8,9,10-tetrahydrothieno[3.2-e]pyrido[4,3-b]indole Chemical class N1C2=CC=C3SC=CC3=C2C2=C1CCNC2 XBBKXEIFGVVLNV-UHFFFAOYSA-N 0.000 abstract 1
- PZOUSPYUWWUPPK-UHFFFAOYSA-N indole Natural products CC1=CC=CC2=C1C=CN2 PZOUSPYUWWUPPK-UHFFFAOYSA-N 0.000 abstract 1
- RKJUIXBNRJVNHR-UHFFFAOYSA-N indolenine Natural products C1=CC=C2CC=NC2=C1 RKJUIXBNRJVNHR-UHFFFAOYSA-N 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
- C07C205/45—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by at least one doubly—bound oxygen atom, not being part of a —CHO group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
- C07C205/49—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
- C07C205/56—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups bound to carbon atoms of six-membered aromatic rings and carboxyl groups bound to acyclic carbon atoms of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D495/14—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Psychiatry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Gasification And Melting Of Waste (AREA)
- Electrotherapy Devices (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19833311342 DE3311342A1 (de) | 1983-03-29 | 1983-03-29 | 7,8,9,10-tetrahydrothieno(3,2-e)pyrido(4,3-b) indole, verfahren zu ihrer herstellung und diese enthaltende arzneimittel |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HUT34198A true HUT34198A (en) | 1985-02-28 |
| HU189102B HU189102B (en) | 1986-06-30 |
Family
ID=6194946
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU841260A HU189102B (en) | 1983-03-29 | 1984-03-29 | Process for the production of 7,8,9,10-tetrahydrothieno/3,2-e/-pyrido/4,3-b/indoles and of therapeutic products containing such compounds |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US4816461A (hu) |
| EP (1) | EP0120439B1 (hu) |
| JP (1) | JPS59184184A (hu) |
| KR (1) | KR840008366A (hu) |
| AT (1) | ATE24912T1 (hu) |
| AU (1) | AU558462B2 (hu) |
| DD (1) | DD222592A5 (hu) |
| DE (2) | DE3311342A1 (hu) |
| DK (1) | DK147384A (hu) |
| ES (1) | ES8504812A1 (hu) |
| FI (1) | FI841221A (hu) |
| GR (1) | GR81878B (hu) |
| HU (1) | HU189102B (hu) |
| IL (1) | IL71345A (hu) |
| NO (1) | NO841084L (hu) |
| PT (1) | PT78326B (hu) |
| YU (1) | YU55084A (hu) |
| ZA (1) | ZA842293B (hu) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3311342A1 (de) * | 1983-03-29 | 1984-10-04 | Troponwerke GmbH & Co KG, 5000 Köln | 7,8,9,10-tetrahydrothieno(3,2-e)pyrido(4,3-b) indole, verfahren zu ihrer herstellung und diese enthaltende arzneimittel |
| EP0499337A1 (en) * | 1991-02-14 | 1992-08-19 | Yamanouchi Europe B.V. | Use of tetra:hydro-thieno-pyrido-indole derivatives for the treatment of skin disorders |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2854014A1 (de) * | 1978-12-14 | 1980-07-03 | Troponwerke Gmbh & Co Kg | 7,8,9,10-tetrahydrothieno eckige klammer auf 3,2-e eckige klammer zu pyrido eckige klammer auf 4,3-b eckige klammer zu indole, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
| DE3311342A1 (de) * | 1983-03-29 | 1984-10-04 | Troponwerke GmbH & Co KG, 5000 Köln | 7,8,9,10-tetrahydrothieno(3,2-e)pyrido(4,3-b) indole, verfahren zu ihrer herstellung und diese enthaltende arzneimittel |
-
1983
- 1983-03-29 DE DE19833311342 patent/DE3311342A1/de not_active Withdrawn
-
1984
- 1984-02-29 DK DK147384A patent/DK147384A/da not_active IP Right Cessation
- 1984-03-20 DE DE8484103031T patent/DE3462037D1/de not_active Expired
- 1984-03-20 NO NO841084A patent/NO841084L/no unknown
- 1984-03-20 EP EP84103031A patent/EP0120439B1/de not_active Expired
- 1984-03-20 AT AT84103031T patent/ATE24912T1/de not_active IP Right Cessation
- 1984-03-21 ES ES530806A patent/ES8504812A1/es not_active Expired
- 1984-03-26 IL IL71345A patent/IL71345A/xx not_active IP Right Cessation
- 1984-03-26 JP JP59056370A patent/JPS59184184A/ja active Pending
- 1984-03-27 GR GR74223A patent/GR81878B/el unknown
- 1984-03-27 FI FI841221A patent/FI841221A/fi not_active Application Discontinuation
- 1984-03-27 DD DD84261281A patent/DD222592A5/de unknown
- 1984-03-28 ZA ZA842293A patent/ZA842293B/xx unknown
- 1984-03-28 YU YU00550/84A patent/YU55084A/xx unknown
- 1984-03-28 PT PT78326A patent/PT78326B/pt unknown
- 1984-03-29 HU HU841260A patent/HU189102B/hu unknown
- 1984-03-29 AU AU26234/84A patent/AU558462B2/en not_active Ceased
- 1984-03-29 KR KR1019840001632A patent/KR840008366A/ko not_active Application Discontinuation
-
1987
- 1987-06-10 US US07/061,255 patent/US4816461A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| FI841221A (fi) | 1984-09-30 |
| DE3311342A1 (de) | 1984-10-04 |
| DD222592A5 (de) | 1985-05-22 |
| PT78326B (en) | 1986-04-30 |
| HU189102B (en) | 1986-06-30 |
| ATE24912T1 (de) | 1987-01-15 |
| DE3462037D1 (en) | 1987-02-19 |
| IL71345A (en) | 1987-11-30 |
| ES530806A0 (es) | 1985-05-01 |
| ZA842293B (en) | 1984-10-31 |
| JPS59184184A (ja) | 1984-10-19 |
| EP0120439B1 (de) | 1987-01-14 |
| KR840008366A (ko) | 1984-12-14 |
| FI841221A0 (fi) | 1984-03-27 |
| PT78326A (en) | 1984-04-01 |
| AU2623484A (en) | 1984-10-04 |
| EP0120439A1 (de) | 1984-10-03 |
| AU558462B2 (en) | 1987-01-29 |
| ES8504812A1 (es) | 1985-05-01 |
| GR81878B (hu) | 1984-12-12 |
| YU55084A (en) | 1986-10-31 |
| NO841084L (no) | 1984-10-01 |
| DK147384D0 (da) | 1984-02-29 |
| DK147384A (da) | 1984-09-30 |
| US4816461A (en) | 1989-03-28 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| PT76107A (en) | Process for preparing new 6-substituted-s-triazolo <3,4-a>phthalazine derivatives and of pharmaceutical compositions containing the same | |
| EP0084164A3 (en) | Derivatives of bicyclic amino acids, process for their preparation, agents containing them and their use, as well as bicyclic amino acids as intermediates, and process for preparing them | |
| IL58775A0 (en) | Hydroxyethyl-azole compounds,their production and pharmaceutical compositions containing them | |
| EP0109020A3 (en) | Derivatives from tricyclic amino acids, process for their preparation, compounds containing them and their use, as well as bicyclic amino acids as intermediates and process for their preparation | |
| PT79220B (en) | Process for preparing new pyridoindole derivatives useful as agents for the treatment of diseases of the centrel nervous system | |
| IL58299A (en) | Fluorine-containing 1,4-dihydropyridine derivatives,their production and their medicinal use | |
| PT78341B (en) | Process for the preparation of new 3-(3,4-di-hydroxyphenyl)-alanine phosphorilates derivatives and compositions for tanning containing then | |
| ES8305684A1 (es) | Procedimiento para la obtencion de derivados aminopropanolicos de 2-hidroxi b-fenil-propiofenonas. | |
| DE2961609D1 (en) | Sila-substituted 1,4-dihydropyridine derivatives, processes for their preparation, pharmaceutical compositions and process for their preparation | |
| DE3364462D1 (en) | Process for the preparation of acemetacin | |
| PT76632A (en) | Process for the preparation of 1-alkyl-1,2,3,4,5,6-hexahydro-azepine <4,5-b> indoles | |
| EG13590A (en) | Process for the production of trans-5-aryl-2,3,4,4a,5,9b-hexahydro-th-pyrido(4,3-b)indoles of use as tranquilizing agents | |
| DE3266022D1 (en) | Process for the preparation of indoles | |
| HUT34198A (en) | Process for the production of 7,8,9,10-tetrahydrothieno/3,2-e/-pyrido/4,3-b/indoles and of therapeutic products containing such compounds | |
| EP0263463A3 (en) | Process for the preparation of 1,4-diazabicycloû2,2,2¨ octanes | |
| HUT36783A (en) | Process for preparing 1,7-diphenyl-3-methyl-aza-7-cyano-8-methyl-nonane | |
| IL59295A0 (en) | Dehydropeptide compounds,their production and pharmaceutical compositions containing them | |
| ES8505357A1 (es) | Un procedimiento para la preparacion de derivados de carboxi-tiazolo (3,2-a) pirimidina nuevos | |
| EP0290862A3 (en) | Process for the preparation of 2,4-diazabicycloû2.2.2¨ octanes | |
| HUT36795A (en) | Process for preparing pyrrolo /3,2,1-hi/indole derivatives and pharmaceutical compositions containing such compounds | |
| PT79025B (en) | Process for the preparation of 1,6-naphthyridin derivatives useful as cardiotonics | |
| DE3464756D1 (en) | Process for the preparation of 7-alkyl indoles | |
| AU648569C (en) | Derivatives of benzofuran, benzothiophene, indole and indolizine, process for their preparation as well as the compositions containing them | |
| PT93971A (pt) | Processo para a preparacao de ariltiazolilimidazoles como antagonistas de 5ht3 |