HUP9903420A2 - Use of fluconazole for the preparation of pharmaceutical compositions, inhibiting the growth of cancers and treating viral infections - Google Patents
Use of fluconazole for the preparation of pharmaceutical compositions, inhibiting the growth of cancers and treating viral infectionsInfo
- Publication number
- HUP9903420A2 HUP9903420A2 HU9903420A HUP9903420A HUP9903420A2 HU P9903420 A2 HUP9903420 A2 HU P9903420A2 HU 9903420 A HU9903420 A HU 9903420A HU P9903420 A HUP9903420 A HU P9903420A HU P9903420 A2 HUP9903420 A2 HU P9903420A2
- Authority
- HU
- Hungary
- Prior art keywords
- viral infections
- preparation
- fluconazole
- cancers
- inhibiting
- Prior art date
Links
- 208000036142 Viral infection Diseases 0.000 title abstract 2
- RFHAOTPXVQNOHP-UHFFFAOYSA-N fluconazole Chemical compound C1=NC=NN1CC(C=1C(=CC(F)=CC=1)F)(O)CN1C=NC=N1 RFHAOTPXVQNOHP-UHFFFAOYSA-N 0.000 title abstract 2
- 238000002360 preparation method Methods 0.000 title abstract 2
- 230000009385 viral infection Effects 0.000 title abstract 2
- 230000005907 cancer growth Effects 0.000 title 1
- 229960004884 fluconazole Drugs 0.000 title 1
- 230000002401 inhibitory effect Effects 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 239000003795 chemical substances by application Substances 0.000 abstract 3
- 102000015790 Asparaginase Human genes 0.000 abstract 1
- 108010024976 Asparaginase Proteins 0.000 abstract 1
- 241000498255 Enterobius vermicularis Species 0.000 abstract 1
- VSNHCAURESNICA-UHFFFAOYSA-N Hydroxyurea Chemical class NC(=O)NO VSNHCAURESNICA-UHFFFAOYSA-N 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 230000000340 anti-metabolite Effects 0.000 abstract 1
- 239000002256 antimetabolite Substances 0.000 abstract 1
- 229940100197 antimetabolite Drugs 0.000 abstract 1
- 239000002246 antineoplastic agent Substances 0.000 abstract 1
- 229960003272 asparaginase Drugs 0.000 abstract 1
- DCXYFEDJOCDNAF-UHFFFAOYSA-M asparaginate Chemical compound [O-]C(=O)C(N)CC(N)=O DCXYFEDJOCDNAF-UHFFFAOYSA-M 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 229940127089 cytotoxic agent Drugs 0.000 abstract 1
- 206010014881 enterobiasis Diseases 0.000 abstract 1
- 239000010643 fennel seed oil Substances 0.000 abstract 1
- 238000010438 heat treatment Methods 0.000 abstract 1
- 230000002452 interceptive effect Effects 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4196—1,2,4-Triazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Abstract
A találmány tárgya a flűkőnazől felhasználása a rák, tűmőrők ésvírűsős fertőzések kezelésére alkalmazható gyógyszerkészítményelőállítására. A készítmény a flűkőnazőlt, 2-(2,4-diflűőr-fenil)-1,3-bisz(1H-1,2,4-triazől-1-il)-prőpan-2-őlt, valamint egy, a DNS-interaktív ágensek, antimetabőlitők, tűbűlin-interaktív ágensek,hőrmőnális ágensek, az aszparagináz vagy hidrőxi-karbamid-származékőkközül választőtt kemőterápiás ágens biztőnságős és hatásősmennyiségét, tővábbá valamilyen gyógyászatilag elfőgadható hőrdőzótés, adőtt esetben, egy pőtenciátőrt tartalmaz. ŕThe subject of the invention is the use of fennel oil for the production of pharmaceutical preparations for the treatment of cancer, pinworms and viral infections. The preparation consists of 2-(2,4-difluorophenyl)-1,3-bis(1H-1,2,4-triazol-1-yl)-propan-2-ol, as well as a DNA- it contains a safe and effective amount of interactive agents, antimetabolites, tübülin-interactive agents, thermal agents, a chemotherapeutic agent selected from asparaginase or hydroxycarbamide derivatives, plus some medicinally preventable heat treatment and, if appropriate, a potentiator. ŕ
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US188995P | 1995-08-04 | 1995-08-04 | |
| US08/674,180 US5908855A (en) | 1996-07-16 | 1996-07-16 | Compositions for treating viral infections |
| PCT/US1996/012474 WO1997005873A2 (en) | 1995-08-04 | 1996-07-30 | Use of fluconazole for inhibiting the growth of cancers |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HUP9903420A2 true HUP9903420A2 (en) | 2000-03-28 |
| HUP9903420A3 HUP9903420A3 (en) | 2001-12-28 |
Family
ID=26669622
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU9903420A HUP9903420A3 (en) | 1995-08-04 | 1996-07-30 | Use of fluconazole for the preparation of pharmaceutical compositions, inhibiting the growth of cancers and treating viral infections |
Country Status (18)
| Country | Link |
|---|---|
| EP (1) | EP0841921A2 (en) |
| JP (1) | JPH11510187A (en) |
| KR (1) | KR19990036138A (en) |
| CN (1) | CN1195288A (en) |
| AR (1) | AR003175A1 (en) |
| AU (1) | AU711966B2 (en) |
| BR (1) | BR9609966A (en) |
| CA (1) | CA2229024A1 (en) |
| CZ (1) | CZ33798A3 (en) |
| HU (1) | HUP9903420A3 (en) |
| IL (1) | IL123095A0 (en) |
| MX (1) | MX9800998A (en) |
| NO (1) | NO980473L (en) |
| NZ (2) | NZ503921A (en) |
| PL (1) | PL324904A1 (en) |
| SK (1) | SK14198A3 (en) |
| TR (2) | TR199800270T1 (en) |
| WO (1) | WO1997005873A2 (en) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6479526B1 (en) | 1995-04-12 | 2002-11-12 | The Procter & Gamble Company | Pharmaceutical composition for inhibiting the growth of viruses and cancers |
| US6177460B1 (en) | 1995-04-12 | 2001-01-23 | The Procter & Gamble Company | Method of treatment for cancer or viral infections |
| US6262093B1 (en) | 1995-04-12 | 2001-07-17 | The Proctor & Gamble Company | Methods of treating cancer with benzimidazoles |
| US6265427B1 (en) | 1995-06-07 | 2001-07-24 | The Proctor & Gamble Company | Pharmaceutical composition for the method of treating leukemia |
| US5770616A (en) | 1995-06-07 | 1998-06-23 | The Procter & Gamble Company | Pharmaceutical composition for inhibiting the growth of cancers |
| US6686391B2 (en) | 1995-08-04 | 2004-02-03 | University Of Arizona Foundation | N-chlorophenylcarbamate and N-chlorophenylthiocarbamate compositions |
| FR2742405B1 (en) * | 1995-12-13 | 1998-02-27 | Cgea Comp Gen Entre Auto | DRIVE UNIT COULD BE COUPLED TO A ROLLING SPEAKER AND RESULTING VEHICLE |
| US5900429A (en) | 1997-01-28 | 1999-05-04 | The Procter & Gamble Company | Method for inhibiting the growth of cancers |
| US6506783B1 (en) | 1997-05-16 | 2003-01-14 | The Procter & Gamble Company | Cancer treatments and pharmaceutical compositions therefor |
| PE11499A1 (en) * | 1997-05-16 | 1999-03-01 | Procter & Gamble | TREATMENT OF HIV AND CANCER |
| US6245789B1 (en) | 1998-05-19 | 2001-06-12 | The Procter & Gamble Company | HIV and viral treatment |
| EP2055313B1 (en) * | 1998-11-09 | 2015-04-29 | Biogen Idec Inc. | Treatment of hematologic malignancies associated with circulating tumor cells using chimeric anti-CD20 antibody |
| US6423734B1 (en) | 1999-08-13 | 2002-07-23 | The Procter & Gamble Company | Method of preventing cancer |
| US6380232B1 (en) | 2000-09-26 | 2002-04-30 | The Procter & Gamble Company | Benzimidazole urea derivatives, and pharmaceutical compositions and unit dosages thereof |
| US6608096B1 (en) | 2000-09-26 | 2003-08-19 | University Of Arizona Foundation | Compounds and methods for use thereof in the treatment of cancer or viral infections |
| US6407105B1 (en) | 2000-09-26 | 2002-06-18 | The Procter & Gamble Company | Compounds and methods for use thereof in the treatment of cancer or viral infections |
| US6462062B1 (en) | 2000-09-26 | 2002-10-08 | The Procter & Gamble Company | Compounds and methods for use thereof in the treatment of cancer or viral infections |
| US7004915B2 (en) * | 2001-08-24 | 2006-02-28 | Kci Licensing, Inc. | Negative pressure assisted tissue treatment system |
| EP1895012A1 (en) | 2006-08-30 | 2008-03-05 | Universitätsklinikum Freiburg | Method for inducing tumor apoptosis by increasing nitric oxide levels |
| WO2008073961A2 (en) * | 2006-12-12 | 2008-06-19 | Emory University | Compounds and methods for modulating the silencing of a polynucleotide of interest |
| WO2019185521A1 (en) * | 2018-03-26 | 2019-10-03 | Westfälische Wilhelms-Universität Münster | Ergosterol-biosynthesis inhibitor and influenza virus infection |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0196855A3 (en) * | 1985-03-29 | 1989-04-12 | Pfizer Inc. | Tioconazole and related compounds for prevention of sexually transmitted diseases and control of herpetic infections |
| BE1004029A6 (en) * | 1990-11-22 | 1992-09-08 | Mol Omer De | Pharmaceutical compound and pharmaceutical set for the treatment of cancer |
| US5565478A (en) * | 1994-03-14 | 1996-10-15 | The United States Of America As Represented By The Department Of Health & Human Services | Combination therapy using signal transduction inhibitors with paclitaxel and other taxane analogs |
| US5665751A (en) * | 1995-06-07 | 1997-09-09 | The Procter & Gamble Company | Pharmaceutical composition for inhibiting the growth of cancers |
-
1996
- 1996-07-30 CN CN96196682A patent/CN1195288A/en active Pending
- 1996-07-30 IL IL12309596A patent/IL123095A0/en unknown
- 1996-07-30 CZ CZ98337A patent/CZ33798A3/en unknown
- 1996-07-30 EP EP96926806A patent/EP0841921A2/en not_active Withdrawn
- 1996-07-30 CA CA002229024A patent/CA2229024A1/en not_active Abandoned
- 1996-07-30 TR TR1998/00270T patent/TR199800270T1/en unknown
- 1996-07-30 NZ NZ503921A patent/NZ503921A/en unknown
- 1996-07-30 HU HU9903420A patent/HUP9903420A3/en unknown
- 1996-07-30 WO PCT/US1996/012474 patent/WO1997005873A2/en not_active Application Discontinuation
- 1996-07-30 NZ NZ315184A patent/NZ315184A/en unknown
- 1996-07-30 AU AU66833/96A patent/AU711966B2/en not_active Ceased
- 1996-07-30 BR BR9609966A patent/BR9609966A/en not_active Application Discontinuation
- 1996-07-30 PL PL96324904A patent/PL324904A1/en unknown
- 1996-07-30 JP JP9508494A patent/JPH11510187A/en active Pending
- 1996-07-30 KR KR1019980700806A patent/KR19990036138A/en not_active IP Right Cessation
- 1996-07-30 SK SK141-98A patent/SK14198A3/en unknown
- 1996-07-30 MX MX9800998A patent/MX9800998A/en not_active Application Discontinuation
- 1996-07-30 TR TR1998/01739T patent/TR199801739T2/en unknown
- 1996-08-02 AR ARP960103860A patent/AR003175A1/en not_active Application Discontinuation
-
1998
- 1998-02-03 NO NO980473A patent/NO980473L/en not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| WO1997005873A2 (en) | 1997-02-20 |
| TR199800270T1 (en) | 1998-05-21 |
| AU6683396A (en) | 1997-03-05 |
| TR199801739T2 (en) | 1998-12-21 |
| AR003175A1 (en) | 1998-07-08 |
| KR19990036138A (en) | 1999-05-25 |
| CN1195288A (en) | 1998-10-07 |
| MX9800998A (en) | 1998-04-30 |
| PL324904A1 (en) | 1998-06-22 |
| NO980473D0 (en) | 1998-02-03 |
| AU711966B2 (en) | 1999-10-28 |
| CA2229024A1 (en) | 1997-02-20 |
| BR9609966A (en) | 1999-02-02 |
| IL123095A0 (en) | 1998-09-24 |
| EP0841921A2 (en) | 1998-05-20 |
| NZ503921A (en) | 2002-03-01 |
| CZ33798A3 (en) | 1998-06-17 |
| HUP9903420A3 (en) | 2001-12-28 |
| SK14198A3 (en) | 1999-03-12 |
| WO1997005873A3 (en) | 1997-03-27 |
| NO980473L (en) | 1998-04-03 |
| JPH11510187A (en) | 1999-09-07 |
| NZ315184A (en) | 2000-05-26 |
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