HUP9903260A2 - 2,4-diaminopyrimidine derivatives with antibiotic activity, preparation and use thereof - Google Patents
2,4-diaminopyrimidine derivatives with antibiotic activity, preparation and use thereofInfo
- Publication number
- HUP9903260A2 HUP9903260A2 HU9903260A HUP9903260A HUP9903260A2 HU P9903260 A2 HUP9903260 A2 HU P9903260A2 HU 9903260 A HU9903260 A HU 9903260A HU P9903260 A HUP9903260 A HU P9903260A HU P9903260 A2 HUP9903260 A2 HU P9903260A2
- Authority
- HU
- Hungary
- Prior art keywords
- preparation
- antibiotic activity
- diaminopyrimidine derivatives
- alkoxy
- alkyl
- Prior art date
Links
- YAAWASYJIRZXSZ-UHFFFAOYSA-N pyrimidine-2,4-diamine Chemical class NC1=CC=NC(N)=N1 YAAWASYJIRZXSZ-UHFFFAOYSA-N 0.000 title abstract 2
- 230000003115 biocidal effect Effects 0.000 title 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 3
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 125000005678 ethenylene group Chemical group [H]C([*:1])=C([H])[*:2] 0.000 abstract 1
- 125000005677 ethinylene group Chemical group [*:2]C#C[*:1] 0.000 abstract 1
- 125000001475 halogen functional group Chemical group 0.000 abstract 1
- 125000001072 heteroaryl group Chemical group 0.000 abstract 1
- 125000004446 heteroarylalkyl group Chemical group 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- AWJUIBRHMBBTKR-UHFFFAOYSA-N iso-quinoline Natural products C1=NC=CC2=CC=CC=C21 AWJUIBRHMBBTKR-UHFFFAOYSA-N 0.000 abstract 1
- 125000002183 isoquinolinyl group Chemical class C1(=NC=CC2=CC=CC=C12)* 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Substituted 2,4-diaminopyrimidines of formula (I), and their salts, are new. Q = ethynylene or vinylene; R1 = 1-6C alkoxy; R2 = Br, OH, or 1-6C alkoxy; R3 = H, 1-6C alkyl, 3-6C cycloalkyl, 6-14C aryl, 5-13C heteroaryl, arylalkyl, heteroarylalkyl, or CN; and R4, R5 = H, 1-6C alkyl or alkoxy, halo, OH, NH2, di(1-6C alkyl)amino, CN, or NO2. Also claimed are substituted isoquinoline intermediates of formula (III).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU9903260A HUP9903260A3 (en) | 1997-05-07 | 1997-05-07 | 2,4-diaminopyrimidine derivatives with antibiotic activity, preparation and use thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU9903260A HUP9903260A3 (en) | 1997-05-07 | 1997-05-07 | 2,4-diaminopyrimidine derivatives with antibiotic activity, preparation and use thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HUP9903260A2 true HUP9903260A2 (en) | 2000-02-28 |
| HUP9903260A3 HUP9903260A3 (en) | 2000-12-28 |
Family
ID=89999456
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU9903260A HUP9903260A3 (en) | 1997-05-07 | 1997-05-07 | 2,4-diaminopyrimidine derivatives with antibiotic activity, preparation and use thereof |
Country Status (1)
| Country | Link |
|---|---|
| HU (1) | HUP9903260A3 (en) |
-
1997
- 1997-05-07 HU HU9903260A patent/HUP9903260A3/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| HUP9903260A3 (en) | 2000-12-28 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AP2002002603A0 (en) | 3-aminoquinazolin-2,4-dione antibacterial agents. | |
| MX9606082A (en) | Oxazolidine derivatives. | |
| YU46303A (en) | 6-0-carbamoyl ketolide derivatives of erythromycin useful as antibacterials | |
| NZ509748A (en) | Nitrogenous heterocyclic carboxamide derivatives or salts useful as antiviral agents | |
| MX9700883A (en) | Substituted quinazoline derivatives. | |
| MXPA03008754A (en) | Pyridine derivatives. | |
| CA2282277A1 (en) | Atropisomers of 3-aryl-4(3h)-quinazolinones and their use as ampa-receptor antagonists | |
| EP1227096A4 (en) | 4-oxoquinolizine antimicrobials having 2-pyridone skeletons as the partial structure | |
| MXPA02006329A (en) | Substituted 8arylquinoline phosphodiesterase4 inhibitors. | |
| IT1315267B1 (en) | DERIVATIVES OF 2- (1H-INDOL-3-IL) -2-OXO-ACETAMIDES FOR ANTI-TUMOR ACTIVITY | |
| DK1086096T3 (en) | Benzamides with tetrahydrofuranyloxy substituents as inhibitors of phosphodiesterase 4 | |
| CA2302943A1 (en) | Phthalazine compounds and therapeutic agents for erectile dysfunction | |
| NO995963L (en) | Carboxamides useful as 5-HTIF agonists | |
| MY136297A (en) | Piperazine derivatives having sst1 antagonistic activity | |
| AU1868692A (en) | Benzomorphan derivatives | |
| BG101601A (en) | Pharmaceutical piperazine compounds | |
| KR100452062B1 (en) | ||
| HUP9903260A2 (en) | 2,4-diaminopyrimidine derivatives with antibiotic activity, preparation and use thereof | |
| AU6164096A (en) | Urokinase receptor ligands | |
| TW350840B (en) | N-acylpiperazine derivative, antibacterial drug and anti-ulcer drug | |
| MX9705649A (en) | Substituted phenyl compounds as endothelin antagonists. | |
| CA2244621A1 (en) | 4-aminopyrrole (3,2-d) pyrimidines as neuropeptide y receptor antagonists | |
| ATE238274T1 (en) | NAPHTHALINE DERIVATIVES | |
| TR200001122T2 (en) | Biphenyl derivatives as pharmaceuticals. | |
| WO2003043582A3 (en) | Modulators of rho c activity |