HUP9902713A2 - Antigen binding fragments that specifically detect cancer cells, nucleotides encoding the fragments, and use thereof for the prophylaxis and detection of cancers - Google Patents
Antigen binding fragments that specifically detect cancer cells, nucleotides encoding the fragments, and use thereof for the prophylaxis and detection of cancersInfo
- Publication number
- HUP9902713A2 HUP9902713A2 HU9902713A HUP9902713A HUP9902713A2 HU P9902713 A2 HUP9902713 A2 HU P9902713A2 HU 9902713 A HU9902713 A HU 9902713A HU P9902713 A HUP9902713 A HU P9902713A HU P9902713 A2 HUP9902713 A2 HU P9902713A2
- Authority
- HU
- Hungary
- Prior art keywords
- fragments
- antigen binding
- antigen
- antibody
- prophylaxis
- Prior art date
Links
- 239000000427 antigen Substances 0.000 title abstract 6
- 102000036639 antigens Human genes 0.000 title abstract 4
- 108091007433 antigens Proteins 0.000 title abstract 4
- 239000012634 fragment Substances 0.000 title abstract 4
- 206010028980 Neoplasm Diseases 0.000 title 2
- 201000011510 cancer Diseases 0.000 title 1
- 238000001514 detection method Methods 0.000 title 1
- 239000002773 nucleotide Substances 0.000 title 1
- 125000003729 nucleotide group Chemical group 0.000 title 1
- 238000011321 prophylaxis Methods 0.000 title 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 5
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 4
- 229920001184 polypeptide Polymers 0.000 abstract 3
- 102000040430 polynucleotide Human genes 0.000 abstract 2
- 108091033319 polynucleotide Proteins 0.000 abstract 2
- 239000002157 polynucleotide Substances 0.000 abstract 2
- 150000001413 amino acids Chemical class 0.000 abstract 1
Landscapes
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Abstract
A novel composition comprises an antigen binding fragment of an antibody (Ab) which specifically recognises C-antigen, where C-antigen is the antigen specifically recognised by an antibody comprising a heavy (H) chain variable (V) region (VH) having a 179 residue sequence and a light (L) chain V region (VL) having a 150 residue sequence. Both sequences are given in the specification. Also claimed are: (1) a polypeptide comprising at least 5 consecutive amino acids of VH or VL, preferably from a CDR; (2) a humanised antibody comprising the polypeptide of (1); (3) a polymeric peptide comprising a number of peptides as in (1); (4) a polynucleotide sequence (I) encoding an antigen binding fragment of an antibody as above; (5) a polynucleotide encoding the polypeptide of (1); (6) a vector containing (I); and (7) a host cell containing (I).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU9902713A HUP9902713A3 (en) | 1997-05-22 | 1997-05-22 | Antigen binding fragments that specifically detect cancer cells, nucleotides encoding the fragments, and use thereof for the prophylaxis and detection of cancers |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU9902713A HUP9902713A3 (en) | 1997-05-22 | 1997-05-22 | Antigen binding fragments that specifically detect cancer cells, nucleotides encoding the fragments, and use thereof for the prophylaxis and detection of cancers |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HUP9902713A2 true HUP9902713A2 (en) | 1999-12-28 |
| HUP9902713A3 HUP9902713A3 (en) | 2000-12-28 |
Family
ID=89999022
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU9902713A HUP9902713A3 (en) | 1997-05-22 | 1997-05-22 | Antigen binding fragments that specifically detect cancer cells, nucleotides encoding the fragments, and use thereof for the prophylaxis and detection of cancers |
Country Status (1)
| Country | Link |
|---|---|
| HU (1) | HUP9902713A3 (en) |
-
1997
- 1997-05-22 HU HU9902713A patent/HUP9902713A3/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| HUP9902713A3 (en) | 2000-12-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD9A | Lapse of provisional protection due to non-payment of fees |