HUP9901795A2 - Eljárások és készítmények immunválasz szuppresszálására II. osztályú fő hisztokompatibilitási komplex (MHC) peptidekkel - Google Patents
Eljárások és készítmények immunválasz szuppresszálására II. osztályú fő hisztokompatibilitási komplex (MHC) peptidekkelInfo
- Publication number
- HUP9901795A2 HUP9901795A2 HU9901795A HUP9901795A HUP9901795A2 HU P9901795 A2 HUP9901795 A2 HU P9901795A2 HU 9901795 A HU9901795 A HU 9901795A HU P9901795 A HUP9901795 A HU P9901795A HU P9901795 A2 HUP9901795 A2 HU P9901795A2
- Authority
- HU
- Hungary
- Prior art keywords
- immune response
- stone
- peptides
- comlex
- mhc
- Prior art date
Links
- 230000028993 immune response Effects 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title 1
- 239000004575 stone Substances 0.000 abstract 3
- 210000001744 T-lymphocyte Anatomy 0.000 abstract 2
- 239000000427 antigen Substances 0.000 abstract 2
- 102000036639 antigens Human genes 0.000 abstract 2
- 108091007433 antigens Proteins 0.000 abstract 2
- 238000006243 chemical reaction Methods 0.000 abstract 2
- 102000007079 Peptide Fragments Human genes 0.000 abstract 1
- 108010033276 Peptide Fragments Proteins 0.000 abstract 1
- 230000004721 adaptive immunity Effects 0.000 abstract 1
- 230000000735 allogeneic effect Effects 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 230000016396 cytokine production Effects 0.000 abstract 1
- 230000036039 immunity Effects 0.000 abstract 1
- 210000004698 lymphocyte Anatomy 0.000 abstract 1
- 238000007799 mixed lymphocyte reaction assay Methods 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 230000035755 proliferation Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/70539—MHC-molecules, e.g. HLA-molecules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Toxicology (AREA)
- Cell Biology (AREA)
- Genetics & Genomics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Gastroenterology & Hepatology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Transplantation (AREA)
- Epidemiology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
A találmány imműnválasz szűppresszálására szőlgáló eljárásőkra éskészítményekre vőnatkőzik, melyek a II. ősztályú főhisztőkőmpatibilitási kőmplex erősen kőnzerválódőtt mőtívűmáttartalmazó peptidfragmenseit tartalmazzák, illetve alkalmazzák. Ezek apeptidek a következő reakciók legalább egyikét, előnyösen mindegyikéthatásősan szűppresszálják: kevert limfőcitareakció vagy T-sejtallőfelismerési reakció; allőantigént felismerő T-sejtek képződése;szöveti antigénnel szembeni limfőcitaprőliferáció; és a limfőcitákstiműlátőrcitőkin-termelése. A csökkenthető vagy szűppresszálhatóimműnválasz allőimműnitás és aűtőimműnitás is lehet. ŕ
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US411795P | 1995-09-21 | 1995-09-21 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HUP9901795A2 true HUP9901795A2 (hu) | 1999-09-28 |
Family
ID=21709234
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU9901795A HUP9901795A2 (hu) | 1995-09-21 | 1996-09-23 | Eljárások és készítmények immunválasz szuppresszálására II. osztályú fő hisztokompatibilitási komplex (MHC) peptidekkel |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP0914041A4 (hu) |
| JP (1) | JPH11513377A (hu) |
| KR (1) | KR19990063637A (hu) |
| AU (1) | AU7202596A (hu) |
| BR (1) | BR9610625A (hu) |
| CA (1) | CA2230119A1 (hu) |
| HU (1) | HUP9901795A2 (hu) |
| IL (1) | IL123759A0 (hu) |
| NO (1) | NO981201D0 (hu) |
| WO (1) | WO1997010711A1 (hu) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7247438B1 (en) | 1997-02-18 | 2007-07-24 | Dana-Farber Cancer Institute | Methods of identifying agents which enhance caspase activity |
| JP2014133703A (ja) * | 2011-03-30 | 2014-07-24 | Clio Inc | 生体組織から単離できるｓｓｅａ−３陽性の多能性幹細胞を含む他家移植用細胞治療用組成物 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH08502244A (ja) * | 1992-08-11 | 1996-03-12 | プレジデント アンド フェローズ オブ ハーバード カレッジ | 免疫調節ペプチド |
-
1996
- 1996-09-23 WO PCT/US1996/015662 patent/WO1997010711A1/en not_active Application Discontinuation
- 1996-09-23 CA CA002230119A patent/CA2230119A1/en not_active Abandoned
- 1996-09-23 HU HU9901795A patent/HUP9901795A2/hu unknown
- 1996-09-23 AU AU72025/96A patent/AU7202596A/en not_active Abandoned
- 1996-09-23 IL IL12375996A patent/IL123759A0/xx unknown
- 1996-09-23 JP JP9512976A patent/JPH11513377A/ja active Pending
- 1996-09-23 KR KR1019980702086A patent/KR19990063637A/ko not_active Application Discontinuation
- 1996-09-23 BR BR9610625A patent/BR9610625A/pt not_active Application Discontinuation
- 1996-09-23 EP EP96933201A patent/EP0914041A4/en not_active Withdrawn
-
1998
- 1998-03-17 NO NO981201A patent/NO981201D0/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EP0914041A4 (en) | 2000-06-28 |
| CA2230119A1 (en) | 1997-03-27 |
| NO981201L (no) | 1998-03-17 |
| KR19990063637A (ko) | 1999-07-26 |
| BR9610625A (pt) | 1999-03-16 |
| WO1997010711A1 (en) | 1997-03-27 |
| IL123759A0 (en) | 1998-10-30 |
| AU7202596A (en) | 1997-04-09 |
| NO981201D0 (no) | 1998-03-17 |
| EP0914041A1 (en) | 1999-05-12 |
| JPH11513377A (ja) | 1999-11-16 |
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