HUP9900016A2 - Stabil liofilizált gyógyszerkészítmény - Google Patents

Stabil liofilizált gyógyszerkészítmény

Info

Publication number
HUP9900016A2
HUP9900016A2 HU9900016A HUP9900016A HUP9900016A2 HU P9900016 A2 HUP9900016 A2 HU P9900016A2 HU 9900016 A HU9900016 A HU 9900016A HU P9900016 A HUP9900016 A HU P9900016A HU P9900016 A2 HUP9900016 A2 HU P9900016A2
Authority
HU
Hungary
Prior art keywords
pharmaceutical formulation
dried pharmaceutical
preparation
stable freeze
mass
Prior art date
Application number
HU9900016A
Other languages
English (en)
Inventor
Colette Bouloumie
Thierry Breul
Laurence Colliere
Philippe Faure
Original Assignee
Sanofi
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR9513022A external-priority patent/FR2740686B1/fr
Application filed by Sanofi filed Critical Sanofi
Publication of HUP9900016A2 publication Critical patent/HUP9900016A2/hu
Publication of HUP9900016A3 publication Critical patent/HUP9900016A3/hu
Publication of HU224987B1 publication Critical patent/HU224987B1/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

A találmány tárgya egy amőrf fázisból és egy kristályős fázisból álló,gyógyszerészetileg alkalmazható liőfilizált készítmény, amely legalábbegy nem fehérje jellegű hatóanyagőt tartalmaz, amely mannitőt ésalanint tartalmaz R arányban, amely 0,1-1 közötti, ahől R a mannittömegének és az alanin tömegének az arányát jelenti, ahől a készítményezen kívül egy vagy több mátrixképző szert is tartalmaz, amely lehetvalamely pektin, zselatin, a szójarőstból készült fehérjekivőnatők éskeverékei kivételével. A találmány az ilyen készítmény előállításárais vőnatkőzik. ŕ
HU9900016A 1995-11-03 1996-10-30 Stable freeze-dried pharmaceutical formulation HU224987B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9513022A FR2740686B1 (fr) 1995-11-03 1995-11-03 Formulation pharmaceutique lyophilisee stable
PCT/FR1996/001706 WO1997017064A1 (fr) 1995-11-03 1996-10-30 Formulation pharmaceutique lyophilisee stable

Publications (3)

Publication Number Publication Date
HUP9900016A2 true HUP9900016A2 (hu) 1999-06-28
HUP9900016A3 HUP9900016A3 (en) 2001-04-28
HU224987B1 HU224987B1 (en) 2006-05-29

Family

ID=37507606

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9900016A HU224987B1 (en) 1995-11-03 1996-10-30 Stable freeze-dried pharmaceutical formulation

Country Status (1)

Country Link
HU (1) HU224987B1 (hu)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8754108B2 (en) 2000-11-22 2014-06-17 Takeda, GmbH Freeze-dried pantoprazole preparation and pantoprazole injection

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8754108B2 (en) 2000-11-22 2014-06-17 Takeda, GmbH Freeze-dried pantoprazole preparation and pantoprazole injection

Also Published As

Publication number Publication date
HUP9900016A3 (en) 2001-04-28
HU224987B1 (en) 2006-05-29

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