HUP2200323A1 - Új avapritinib sók és elõállítási eljárásaik - Google Patents

Új avapritinib sók és elõállítási eljárásaik

Info

Publication number
HUP2200323A1
HUP2200323A1 HU2200323A HUP2200323A HUP2200323A1 HU P2200323 A1 HUP2200323 A1 HU P2200323A1 HU 2200323 A HU2200323 A HU 2200323A HU P2200323 A HUP2200323 A HU P2200323A HU P2200323 A1 HUP2200323 A1 HU P2200323A1
Authority
HU
Hungary
Prior art keywords
salts
avapritinib
preparing
novel
methods
Prior art date
Application number
HU2200323A
Other languages
English (en)
Inventor
Andras Demjen
Bertha Ferenc Dr
Detrich Adam Dr
Monika Teller
Zoltan Varga
Sipos Eva Dr
Daniel Enesei
Original Assignee
Egyt Gyogyszervegyeszeti Gyar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Egyt Gyogyszervegyeszeti Gyar filed Critical Egyt Gyogyszervegyeszeti Gyar
Priority to HU2200323A priority Critical patent/HUP2200323A1/hu
Priority to PCT/HU2023/050049 priority patent/WO2024033668A1/en
Publication of HUP2200323A1 publication Critical patent/HUP2200323A1/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/235—Saturated compounds containing more than one carboxyl group
    • C07C59/245—Saturated compounds containing more than one carboxyl group containing hydroxy or O-metal groups
    • C07C59/265—Citric acid

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HU2200323A 2022-08-11 2022-08-11 Új avapritinib sók és elõállítási eljárásaik HUP2200323A1 (hu)

Priority Applications (2)

Application Number Priority Date Filing Date Title
HU2200323A HUP2200323A1 (hu) 2022-08-11 2022-08-11 Új avapritinib sók és elõállítási eljárásaik
PCT/HU2023/050049 WO2024033668A1 (en) 2022-08-11 2023-08-10 Novel avapritinib salts and methods for preparing the salts

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU2200323A HUP2200323A1 (hu) 2022-08-11 2022-08-11 Új avapritinib sók és elõállítási eljárásaik

Publications (1)

Publication Number Publication Date
HUP2200323A1 true HUP2200323A1 (hu) 2024-02-28

Family

ID=89851060

Family Applications (1)

Application Number Title Priority Date Filing Date
HU2200323A HUP2200323A1 (hu) 2022-08-11 2022-08-11 Új avapritinib sók és elõállítási eljárásaik

Country Status (2)

Country Link
HU (1) HUP2200323A1 (hu)
WO (1) WO2024033668A1 (hu)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3136707A1 (en) * 2019-04-12 2020-10-15 Blueprint Medicines Corporation Crystalline forms of (s)-1-(4-fluorophenyl)-1-(2-(4-(6-(1-methyl-1h-pyrazol-4-yl)pyrrolo[2,1-f][1,2,4]triazin-4-yl)piperazinyl)-pyrimidin-5-yl)ethan-1-amine and methods of making
EP4118084A1 (en) * 2020-03-11 2023-01-18 Teva Czech Industries s.r.o. Solid state forms of avapritinib and process for preparation thereof
US20230279009A1 (en) * 2020-06-17 2023-09-07 Teva Czech Industries S.R.O Solid state forms of avapritinib salts

Also Published As

Publication number Publication date
WO2024033668A1 (en) 2024-02-15

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