HUP2100005A1 - Rheumatoid arthrits páciensek biológiai terápiára adott válasz készségének becslése - Google Patents

Rheumatoid arthrits páciensek biológiai terápiára adott válasz készségének becslése

Info

Publication number
HUP2100005A1
HUP2100005A1 HU2100005A HUP2100005A HUP2100005A1 HU P2100005 A1 HUP2100005 A1 HU P2100005A1 HU 2100005 A HU2100005 A HU 2100005A HU P2100005 A HUP2100005 A HU P2100005A HU P2100005 A1 HUP2100005 A1 HU P2100005A1
Authority
HU
Hungary
Prior art keywords
rheumatoid arthritis
biological treatment
arthritis patients
assessing responsiveness
responsiveness
Prior art date
Application number
HU2100005A
Other languages
English (en)
Inventor
Gergely Toldi
Kata Filkor
Peter Szeremy
Andras Apjok
Zoltan Szekanecz
Original Assignee
Navolab Diagnosztika Kft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from EP18172478.2A external-priority patent/EP3570028A1/en
Priority claimed from HU1800184A external-priority patent/HUP1800184A1/hu
Application filed by Navolab Diagnosztika Kft filed Critical Navolab Diagnosztika Kft
Publication of HUP2100005A1 publication Critical patent/HUP2100005A1/hu

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • G01N33/5047Cells of the immune system
    • G01N33/505Cells of the immune system involving T-cells
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/6428Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/564Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/6428Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G01N2021/6439Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705Assays involving receptors, cell surface antigens or cell surface determinants
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/10Musculoskeletal or connective tissue disorders
    • G01N2800/101Diffuse connective tissue disease, e.g. Sjögren, Wegener's granulomatosis
    • G01N2800/102Arthritis; Rheumatoid arthritis, i.e. inflammation of peripheral joints
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/52Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Toxicology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rehabilitation Therapy (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Optics & Photonics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
HU2100005A 2018-05-15 2019-05-15 Rheumatoid arthrits páciensek biológiai terápiára adott válasz készségének becslése HUP2100005A1 (hu)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP18172478.2A EP3570028A1 (en) 2018-05-15 2018-05-15 Assessing responsiveness of rheumatoid arthritis patients to biological treatment
HU1800184A HUP1800184A1 (hu) 2018-05-30 2018-05-30 Rheumatoid arthritis betegek biológiai terápiára adott válasz készségének becslése
PCT/HU2019/050025 WO2019220158A1 (en) 2018-05-15 2019-05-15 Assessing responsiveness of rheumatoid arthritis patients to biological treatment

Publications (1)

Publication Number Publication Date
HUP2100005A1 true HUP2100005A1 (hu) 2021-03-29

Family

ID=89992700

Family Applications (1)

Application Number Title Priority Date Filing Date
HU2100005A HUP2100005A1 (hu) 2018-05-15 2019-05-15 Rheumatoid arthrits páciensek biológiai terápiára adott válasz készségének becslése

Country Status (4)

Country Link
US (1) US20210382049A1 (hu)
EP (1) EP3794347A1 (hu)
HU (1) HUP2100005A1 (hu)
WO (1) WO2019220158A1 (hu)

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU217108B (hu) 1994-08-31 1999-11-29 SOLVO Biotechnológiai Kft. Eljárás daganatok multidrogrezisztenciáját okozó fehérje aktivitásának in vitro mennyiségi kimutatására biológiai mintákban
WO2012061620A1 (en) 2010-11-04 2012-05-10 Genentech, Inc. Methods for treating, diagnosing, and monitoring rheumatoid arthritis
JPWO2015083765A1 (ja) 2013-12-04 2017-03-16 国立大学法人大阪大学 生物学的製剤による関節リウマチの治療効果を予測判定する方法
EP2980587A1 (en) 2014-08-01 2016-02-03 Fundació Hospital Universitari Vall d' Hebron - Institut de Recerca Method to predict response to treatment with anti-TNF alpha agents
WO2016015779A1 (en) 2014-08-01 2016-02-04 Fundació Hospital Universitari Vall D'hebron - Institut De Recerca Method to predict the lack of response to anti-tnf alpha therapies
US11644473B2 (en) 2016-04-15 2023-05-09 Rowan University Serum biomarkers for predicting and evaluating response to TNF inhibitor therapy in rheumatoid arthritis patients

Also Published As

Publication number Publication date
US20210382049A1 (en) 2021-12-09
WO2019220158A1 (en) 2019-11-21
EP3794347A1 (en) 2021-03-24

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