HUP1200327A2 - Use of affinity materials having surface modified by metal complexing ligands and stability increasing groups, and lanthanide metal ions for peptid absorption and purification - Google Patents

Use of affinity materials having surface modified by metal complexing ligands and stability increasing groups, and lanthanide metal ions for peptid absorption and purification

Info

Publication number
HUP1200327A2
HUP1200327A2 HU1200327A HUP1200327A HUP1200327A2 HU P1200327 A2 HUP1200327 A2 HU P1200327A2 HU 1200327 A HU1200327 A HU 1200327A HU P1200327 A HUP1200327 A HU P1200327A HU P1200327 A2 HUP1200327 A2 HU P1200327A2
Authority
HU
Hungary
Prior art keywords
peptid
purification
absorption
surface modified
metal ions
Prior art date
Application number
HU1200327A
Other languages
English (en)
Inventor
Laszlo Dr Poppe
Zoltan Boros
Beata Dr Vertessy
Klaudia Kovacs
Alexandra Toth
Gabor Dr Hornyanszky
Jozsef Dr Nagy
Balazs Dr Erdelyi
Dr Bodai Viktoria Erdelyine
Peter Dr Satorhelyi
Original Assignee
Budapesti Mueszaki Es Gazdasagtudomanyi Egyetem
Fermentia Mikrobiologiai Kft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Budapesti Mueszaki Es Gazdasagtudomanyi Egyetem, Fermentia Mikrobiologiai Kft filed Critical Budapesti Mueszaki Es Gazdasagtudomanyi Egyetem
Priority to HU1200327A priority Critical patent/HU230585B1/hu
Priority to PCT/HU2013/000050 priority patent/WO2013179072A1/en
Priority to EP13734148.3A priority patent/EP2943501B1/en
Publication of HUP1200327A2 publication Critical patent/HUP1200327A2/hu
Publication of HU230585B1 publication Critical patent/HU230585B1/hu

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 - B01D15/36
    • B01D15/3804—Affinity chromatography
    • B01D15/3828—Ligand exchange chromatography, e.g. complexation, chelation or metal interaction chromatography
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/286—Phases chemically bonded to a substrate, e.g. to silica or to polymers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3202—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the carrier, support or substrate used for impregnation or coating
    • B01J20/3204—Inorganic carriers, supports or substrates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3202—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the carrier, support or substrate used for impregnation or coating
    • B01J20/3206—Organic carriers, supports or substrates
    • B01J20/3208—Polymeric carriers, supports or substrates
    • B01J20/3212—Polymeric carriers, supports or substrates consisting of a polymer obtained by reactions otherwise than involving only carbon to carbon unsaturated bonds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3214—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the method for obtaining this coating or impregnating
    • B01J20/3217—Resulting in a chemical bond between the coating or impregnating layer and the carrier, support or substrate, e.g. a covalent bond
    • B01J20/3219—Resulting in a chemical bond between the coating or impregnating layer and the carrier, support or substrate, e.g. a covalent bond involving a particular spacer or linking group, e.g. for attaching an active group
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3244—Non-macromolecular compounds
    • B01J20/3265—Non-macromolecular compounds with an organic functional group containing a metal, e.g. a metal affinity ligand
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
HU1200327A 2012-05-30 2012-05-30 Fehérjék megkötésére és elválasztására alkalmas lantanida fémionokkal komplexált hordozók HU230585B1 (hu)

Priority Applications (3)

Application Number Priority Date Filing Date Title
HU1200327A HU230585B1 (hu) 2012-05-30 2012-05-30 Fehérjék megkötésére és elválasztására alkalmas lantanida fémionokkal komplexált hordozók
PCT/HU2013/000050 WO2013179072A1 (en) 2012-05-30 2013-05-30 Compositions for binding and separating of proteins
EP13734148.3A EP2943501B1 (en) 2012-05-30 2013-05-30 Compositions for binding and separating of proteins

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU1200327A HU230585B1 (hu) 2012-05-30 2012-05-30 Fehérjék megkötésére és elválasztására alkalmas lantanida fémionokkal komplexált hordozók

Publications (2)

Publication Number Publication Date
HUP1200327A2 true HUP1200327A2 (en) 2013-12-30
HU230585B1 HU230585B1 (hu) 2017-01-30

Family

ID=89990756

Family Applications (1)

Application Number Title Priority Date Filing Date
HU1200327A HU230585B1 (hu) 2012-05-30 2012-05-30 Fehérjék megkötésére és elválasztására alkalmas lantanida fémionokkal komplexált hordozók

Country Status (3)

Country Link
EP (1) EP2943501B1 (hu)
HU (1) HU230585B1 (hu)
WO (1) WO2013179072A1 (hu)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116351399A (zh) * 2022-12-30 2023-06-30 厦门色谱分析仪器有限公司 一种键合型纤维素衍生物手性液相色谱柱及其制备方法和应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US662365A (en) 1900-06-14 1900-11-20 Clarence C Marder Printer's rule.
CA1231306A (en) 1983-03-03 1988-01-12 Erich Hochuli Purification of interferon
US4569794A (en) 1984-12-05 1986-02-11 Eli Lilly And Company Process for purifying proteins and compounds useful in such process
CA1259312A (en) 1985-11-11 1989-09-12 Jaroslav Kahovec Silane reagents containing a complexion grouping and inorganic material modified with these reagents
CA1304886C (en) 1986-07-10 1992-07-07 Heinz Dobeli Metal chelate resins
US5594115A (en) 1990-04-09 1997-01-14 Pharmacia & Upjohn Company Process of purifying recombinant proteins and compounds useful in such process
US6623655B1 (en) 2000-04-24 2003-09-23 Sigma-Aldrich Co. Metal chelating compositions
AU2003286514A1 (en) 2002-10-18 2004-05-04 Promega Corporation Composition for separating molecules
SE526214C2 (sv) 2003-02-28 2005-07-26 Amersham Biosciences Ab Ett sätt att generera metallkelaterande affinitetsligander
WO2009019012A2 (en) * 2007-08-06 2009-02-12 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Immobilisation of chelating groups for immobilised metal ion chromatography (imac)

Also Published As

Publication number Publication date
EP2943501B1 (en) 2019-06-26
EP2943501A1 (en) 2015-11-18
WO2013179072A8 (en) 2016-03-31
WO2013179072A1 (en) 2013-12-05
HU230585B1 (hu) 2017-01-30

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Legal Events

Date Code Title Description
MM4A Lapse of definitive patent protection due to non-payment of fees