HUP0401610A2 - 4-[Fenil-(4-piperidinil)-amino]-benzamid-származékok, alkalmazásuk, eljárás az előállításukra és ezeket tartalmazó gyógyszerkészítmények - Google Patents
4-[Fenil-(4-piperidinil)-amino]-benzamid-származékok, alkalmazásuk, eljárás az előállításukra és ezeket tartalmazó gyógyszerkészítmények Download PDFInfo
- Publication number
- HUP0401610A2 HUP0401610A2 HU0401610A HUP0401610A HUP0401610A2 HU P0401610 A2 HUP0401610 A2 HU P0401610A2 HU 0401610 A HU0401610 A HU 0401610A HU P0401610 A HUP0401610 A HU P0401610A HU P0401610 A2 HUP0401610 A2 HU P0401610A2
- Authority
- HU
- Hungary
- Prior art keywords
- phenyl
- amino
- methyl
- diisopropylcarbamoyl
- piperidin
- Prior art date
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- 238000002360 preparation method Methods 0.000 title claims description 16
- 239000008194 pharmaceutical composition Substances 0.000 title claims description 9
- YFKZHFPNQFEPHF-UHFFFAOYSA-N 4-(n-piperidin-4-ylanilino)benzamide Chemical class C1=CC(C(=O)N)=CC=C1N(C=1C=CC=CC=1)C1CCNCC1 YFKZHFPNQFEPHF-UHFFFAOYSA-N 0.000 title description 2
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- 229920001277 pectin Polymers 0.000 description 1
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- RGCLLPNLLBQHPF-HJWRWDBZSA-N phosphamidon Chemical compound CCN(CC)C(=O)C(\Cl)=C(/C)OP(=O)(OC)OC RGCLLPNLLBQHPF-HJWRWDBZSA-N 0.000 description 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 1
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- 239000011780 sodium chloride Substances 0.000 description 1
- BEOOHQFXGBMRKU-UHFFFAOYSA-N sodium cyanoborohydride Chemical compound [Na+].[B-]C#N BEOOHQFXGBMRKU-UHFFFAOYSA-N 0.000 description 1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/56—Nitrogen atoms
- C07D211/58—Nitrogen atoms attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0101773A SE0101773D0 (sv) | 2001-05-18 | 2001-05-18 | Novel compounds |
| PCT/SE2002/000957 WO2002094785A1 (en) | 2001-05-18 | 2002-05-16 | 4-(phenyl-(piperidin-4-yl)-amino)-benzamide derivatives and their use for the treatment of pain, anxiety or gastrointestinal disorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HUP0401610A2 true HUP0401610A2 (hu) | 2004-12-28 |
Family
ID=20284176
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU0401610A HUP0401610A2 (hu) | 2001-05-18 | 2002-05-16 | 4-[Fenil-(4-piperidinil)-amino]-benzamid-származékok, alkalmazásuk, eljárás az előállításukra és ezeket tartalmazó gyógyszerkészítmények |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US7008952B2 (enExample) |
| EP (1) | EP1395557A1 (enExample) |
| JP (1) | JP2005508291A (enExample) |
| KR (1) | KR20040000472A (enExample) |
| CN (1) | CN1527818A (enExample) |
| AR (1) | AR036231A1 (enExample) |
| BG (1) | BG108334A (enExample) |
| BR (1) | BR0209665A (enExample) |
| CA (1) | CA2446516A1 (enExample) |
| CO (1) | CO5540320A2 (enExample) |
| CZ (1) | CZ20033093A3 (enExample) |
| EE (1) | EE200300526A (enExample) |
| HU (1) | HUP0401610A2 (enExample) |
| IL (1) | IL158700A0 (enExample) |
| IS (1) | IS7033A (enExample) |
| MX (1) | MXPA03010444A (enExample) |
| NO (1) | NO20035119D0 (enExample) |
| PL (1) | PL367246A1 (enExample) |
| RU (1) | RU2003131963A (enExample) |
| SE (1) | SE0101773D0 (enExample) |
| SK (1) | SK13992003A3 (enExample) |
| WO (1) | WO2002094785A1 (enExample) |
| ZA (1) | ZA200308642B (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101921279A (zh) | 2003-10-01 | 2010-12-22 | 阿得罗公司 | 螺环杂环衍生物及其应用方法 |
| US7598261B2 (en) | 2005-03-31 | 2009-10-06 | Adolor Corporation | Spirocyclic heterocyclic derivatives and methods of their use |
| US7576207B2 (en) | 2006-04-06 | 2009-08-18 | Adolor Corporation | Spirocyclic heterocyclic derivatives and methods of their use |
| CN113979997A (zh) * | 2021-11-12 | 2022-01-28 | 中国科学院昆明植物研究所 | N,n-(4-哌啶基、芳基)-3-氨基苯酚类衍生物及其药物组合物和其应用 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4091096A (en) | 1976-03-19 | 1978-05-23 | Eli Lilly And Company | Dinitroanilines for the control of phytopathogens |
| EG12406A (en) | 1976-08-12 | 1979-03-31 | Janssen Pharmaceutica Nv | Process for preparing of novel n-aryl-n-(1-l-4-piperidinyl)-arylacetamides |
| SE441448B (sv) | 1977-05-23 | 1985-10-07 | Pfizer | Sett att framstella hexahydro-gamma-karbolinforeningar |
| US4252812A (en) | 1977-05-23 | 1981-02-24 | Pfizer Inc. | 2-Substituted-trans-5-aryl-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indoles |
| DE3200304A1 (de) | 1981-01-16 | 1982-08-26 | Sandoz-Patent-GmbH, 7850 Lörrach | 3-aminopropoxyaryl-derivate, ihre herstellung und sie enthaltende arzneimittel |
| DE3563964D1 (en) | 1984-10-16 | 1988-09-01 | Synthelabo | Piperidine derivatives, their preparation and their therapeutical application |
| YU150489A (sh) | 1989-08-10 | 1992-12-21 | W.L. Gore & Co. Gmbh. | Uređaj za ispitivanje odevnih predmeta na nepromočivost |
| KR940003491B1 (ko) | 1989-08-10 | 1994-04-23 | 리히터 게데온 베기에스제티 기아르 알.티 | 4,4-이중 치환된 피페리딘 유도체와 그 제조방법 및 상기 화합물을 함유하는 약제학적 조성물 |
| US5854245A (en) | 1996-06-28 | 1998-12-29 | Merck & Co., Inc. | Fibrinogen receptor antagonists |
| TW548271B (en) * | 1996-12-20 | 2003-08-21 | Astra Pharma Inc | Novel piperidine derivatives having an exocyclic double bond with analgesic effects |
| SE9604786D0 (sv) | 1996-12-20 | 1996-12-20 | Astra Pharma Inc | New compounds |
| DK1049676T3 (da) | 1997-12-24 | 2006-01-16 | Ortho Mcneil Pharm Inc | 4-[Aryl(piperidin-4-yl)]aminobenzamider, som binder til delta-opioidreceptoren |
| CA2683097A1 (en) | 1998-03-10 | 1999-09-16 | Research Triangle Institute | Novel opiate compounds, methods of making and methods of use |
| SE9904675D0 (sv) * | 1999-12-20 | 1999-12-20 | Astra Pharma Inc | Novel compounds |
| US6552036B2 (en) * | 2000-03-03 | 2003-04-22 | Ortho-Mcneil Pharmaceutical, Inc. | 3-(Diarylmethylene)-8-azabicyclo[3.2.1]octane derivatives |
| SE0001207D0 (sv) * | 2000-04-04 | 2000-04-04 | Astrazeneca Canada Inc | Novel compounds |
-
2001
- 2001-05-18 SE SE0101773A patent/SE0101773D0/xx unknown
-
2002
- 2002-05-16 MX MXPA03010444A patent/MXPA03010444A/es unknown
- 2002-05-16 CA CA002446516A patent/CA2446516A1/en not_active Abandoned
- 2002-05-16 JP JP2002591458A patent/JP2005508291A/ja active Pending
- 2002-05-16 WO PCT/SE2002/000957 patent/WO2002094785A1/en not_active Ceased
- 2002-05-16 EE EEP200300526A patent/EE200300526A/xx unknown
- 2002-05-16 BR BR0209665-0A patent/BR0209665A/pt not_active Application Discontinuation
- 2002-05-16 US US10/477,636 patent/US7008952B2/en not_active Expired - Fee Related
- 2002-05-16 HU HU0401610A patent/HUP0401610A2/hu unknown
- 2002-05-16 EP EP02733713A patent/EP1395557A1/en not_active Withdrawn
- 2002-05-16 PL PL02367246A patent/PL367246A1/xx not_active Application Discontinuation
- 2002-05-16 AR ARP020101818A patent/AR036231A1/es not_active Application Discontinuation
- 2002-05-16 CN CNA028141687A patent/CN1527818A/zh active Pending
- 2002-05-16 CZ CZ20033093A patent/CZ20033093A3/cs unknown
- 2002-05-16 KR KR10-2003-7014951A patent/KR20040000472A/ko not_active Withdrawn
- 2002-05-16 SK SK1399-2003A patent/SK13992003A3/sk unknown
- 2002-05-16 IL IL15870002A patent/IL158700A0/xx unknown
- 2002-05-16 RU RU2003131963/04A patent/RU2003131963A/ru not_active Application Discontinuation
-
2003
- 2003-11-05 ZA ZA200308642A patent/ZA200308642B/en unknown
- 2003-11-07 BG BG108334A patent/BG108334A/bg unknown
- 2003-11-12 CO CO03100170A patent/CO5540320A2/es not_active Application Discontinuation
- 2003-11-13 IS IS7033A patent/IS7033A/is unknown
- 2003-11-17 NO NO20035119A patent/NO20035119D0/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| BG108334A (bg) | 2004-12-30 |
| IS7033A (is) | 2003-11-13 |
| IL158700A0 (en) | 2004-05-12 |
| SE0101773D0 (sv) | 2001-05-18 |
| CA2446516A1 (en) | 2002-11-28 |
| RU2003131963A (ru) | 2005-05-10 |
| KR20040000472A (ko) | 2004-01-03 |
| EE200300526A (et) | 2004-02-16 |
| WO2002094785A1 (en) | 2002-11-28 |
| JP2005508291A (ja) | 2005-03-31 |
| AR036231A1 (es) | 2004-08-25 |
| MXPA03010444A (es) | 2004-03-09 |
| ZA200308642B (en) | 2005-02-07 |
| US7008952B2 (en) | 2006-03-07 |
| US20040142966A1 (en) | 2004-07-22 |
| NO20035119D0 (no) | 2003-11-17 |
| BR0209665A (pt) | 2004-04-20 |
| CO5540320A2 (es) | 2005-07-29 |
| CZ20033093A3 (cs) | 2004-07-14 |
| EP1395557A1 (en) | 2004-03-10 |
| SK13992003A3 (sk) | 2004-04-06 |
| PL367246A1 (en) | 2005-02-21 |
| CN1527818A (zh) | 2004-09-08 |
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