HUP0400531A2 - Hydantoin compounds useful as anti-inflammatory agents and pharmaceutical compositions containing them - Google Patents
Hydantoin compounds useful as anti-inflammatory agents and pharmaceutical compositions containing themInfo
- Publication number
- HUP0400531A2 HUP0400531A2 HU0400531A HUP0400531A HUP0400531A2 HU P0400531 A2 HUP0400531 A2 HU P0400531A2 HU 0400531 A HU0400531 A HU 0400531A HU P0400531 A HUP0400531 A HU P0400531A HU P0400531 A2 HUP0400531 A2 HU P0400531A2
- Authority
- HU
- Hungary
- Prior art keywords
- pharmaceutical compositions
- compositions containing
- inflammatory agents
- compounds useful
- hydantoin compounds
- Prior art date
Links
- 229940121363 anti-inflammatory agent Drugs 0.000 title 1
- 239000002260 anti-inflammatory agent Substances 0.000 title 1
- 150000001469 hydantoins Chemical class 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 2
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 125000002837 carbocyclic group Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 1
- 208000026278 immune system disease Diseases 0.000 abstract 1
- 208000027866 inflammatory disease Diseases 0.000 abstract 1
- 230000002757 inflammatory effect Effects 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229920006395 saturated elastomer Polymers 0.000 abstract 1
- 125000000547 substituted alkyl group Chemical group 0.000 abstract 1
- 125000004434 sulfur atom Chemical group 0.000 abstract 1
Abstract
A találmány tárgyát gyulladásos vagy immunbetegségek kezelésérealkalmazható általános képletű vegyületek - ahol A heterociklusos vagykarbociklusos telített gyűrű; L és K oxigén- vagy kénatom; Mnitrogénatom vagy =CH- csoport; Y nitrogénatom vagy =CH- csoport; Zhidrogénatom, alkil- vagy szubsztituált alkilcsoport; R1-R4 a szerveskémiában ismert egyszerű vagy összetett csoport; n = 0, 1 vagy 2; r =1, 2 vagy 3; és s = 0, 1 vagy 2 - és gyógyszerészetileg elfogadhatósóik, valamint ezeket tartalmazó gyógyszerkészítmények képezik. ÓThe subject of the invention are compounds of the general formula applicable to the treatment of inflammatory or immune diseases - where A is a heterocyclic or carbocyclic saturated ring; L and K are oxygen or sulfur atoms; Nitrogen atom or =CH- group; Y nitrogen atom or =CH- group; Hydrogen, alkyl or substituted alkyl; R1-R4 is a simple or complex group known in organic chemistry; n = 0, 1 or 2; r = 1, 2 or 3; and s = 0, 1 or 2 - and their pharmaceutically acceptable salts, as well as pharmaceutical preparations containing them. HE
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US25048600P | 2000-12-01 | 2000-12-01 | |
| US25065300P | 2000-12-01 | 2000-12-01 | |
| US72716501P | 2001-02-28 | 2001-02-28 | |
| PCT/US2001/045540 WO2002044181A1 (en) | 2000-12-01 | 2001-11-30 | Hydantoin compounds useful as anti-inflammatory agents |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HUP0400531A2 true HUP0400531A2 (en) | 2004-06-28 |
| HUP0400531A3 HUP0400531A3 (en) | 2006-05-29 |
Family
ID=28457726
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU0400531A HUP0400531A3 (en) | 2000-12-01 | 2001-11-30 | Hydantoin compounds useful as anti-inflammatory agents and pharmaceutical compositions containing them |
Country Status (3)
| Country | Link |
|---|---|
| JP (1) | JP2004519435A (en) |
| CA (1) | CA2436943A1 (en) |
| HU (1) | HUP0400531A3 (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8501768B2 (en) * | 2011-05-17 | 2013-08-06 | Hoffmann-La Roche Inc. | Hexahydrocyclopentapyrrolone, hexahydropyrrolopyrrolone, octahydropyrrolopyridinone and octahydropyridinone compounds |
-
2001
- 2001-11-30 HU HU0400531A patent/HUP0400531A3/en unknown
- 2001-11-30 CA CA002436943A patent/CA2436943A1/en not_active Abandoned
- 2001-11-30 JP JP2002546551A patent/JP2004519435A/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CA2436943A1 (en) | 2003-06-06 |
| HUP0400531A3 (en) | 2006-05-29 |
| JP2004519435A (en) | 2004-07-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD9A | Lapse of provisional protection due to non-payment of fees |