HUP0202438A2 - Pharmaceutical compositions containing thiazolidinedione derivatives and process for their preparation - Google Patents

Pharmaceutical compositions containing thiazolidinedione derivatives and process for their preparation

Info

Publication number
HUP0202438A2
HUP0202438A2 HU0202438A HUP0202438A HUP0202438A2 HU P0202438 A2 HUP0202438 A2 HU P0202438A2 HU 0202438 A HU0202438 A HU 0202438A HU P0202438 A HUP0202438 A HU P0202438A HU P0202438 A2 HUP0202438 A2 HU P0202438A2
Authority
HU
Hungary
Prior art keywords
preparation
compounds
pharmaceutical compositions
compositions containing
thiazolidinedione derivatives
Prior art date
Application number
HU0202438A
Other languages
Hungarian (hu)
Inventor
Robin Edwin Buckingham
Michael Urquhart
Original Assignee
Smithkline Beecham Plc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9919465.6A external-priority patent/GB9919465D0/en
Priority claimed from GBGB9919842.6A external-priority patent/GB9919842D0/en
Priority claimed from GBGB9920149.3A external-priority patent/GB9920149D0/en
Application filed by Smithkline Beecham Plc. filed Critical Smithkline Beecham Plc.
Publication of HUP0202438A2 publication Critical patent/HUP0202438A2/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Abstract

A találmány (I) általános képletű vegyületeket - amelyek képletében A1jelentése -OH vagy -OSO2OH képletű csoport; R1 jelentése hidrogénatomvagy 1-6 szénatomos alkilcsoport; valamint R2 és R3 mindegyikénekjelentése hidrogénatom, vagy R2 és R3 együtt egy kémiai kötést jelent vagy a vegyületeknek egy tautomer formáját és/vagy gyógyászatilagelfogadható sóját és/vagy gyógyászatilag elfogadható szolvátjáttartalmazó gyógyszerkészítményekre, (I) általános képletű újvegyületekre, a gyógyszerkészítmények és a vegyületek előállítására,valamint gyógyászati felhasználására vonatkozik. ÓThe compounds of the general formula (I) of the invention - in the formula of which A1 means a group of the formula -OH or -OSO2OH; R1 is a hydrogen atom or a C1-C6 alkyl group; and each of R2 and R3 is a hydrogen atom, or R2 and R3 together represent a chemical bond or a tautomeric form of the compounds and/or a pharmaceutically acceptable salt and/or a pharmaceutically acceptable solvate for pharmaceutical preparations, new compounds of general formula (I), the preparation of pharmaceutical preparations and compounds, as well as refers to its medicinal use. HE

HU0202438A 1999-08-17 2000-08-14 Pharmaceutical compositions containing thiazolidinedione derivatives and process for their preparation HUP0202438A2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GBGB9919465.6A GB9919465D0 (en) 1999-08-17 1999-08-17 Novel compounds
GBGB9919842.6A GB9919842D0 (en) 1999-08-20 1999-08-20 Novel compounds
GBGB9920149.3A GB9920149D0 (en) 1999-08-25 1999-08-25 Novel compounds
PCT/EP2000/007926 WO2001012628A1 (en) 1999-08-17 2000-08-14 Pharmaceutical compositions containing thiazolidinedione derivatives and process for their preparation

Publications (1)

Publication Number Publication Date
HUP0202438A2 true HUP0202438A2 (en) 2002-12-28

Family

ID=27269792

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0202438A HUP0202438A2 (en) 1999-08-17 2000-08-14 Pharmaceutical compositions containing thiazolidinedione derivatives and process for their preparation

Country Status (15)

Country Link
EP (1) EP1202991A1 (en)
JP (1) JP2003507379A (en)
KR (1) KR20020022812A (en)
CN (1) CN1379776A (en)
AU (1) AU7408900A (en)
BR (1) BR0013375A (en)
CA (1) CA2381976A1 (en)
CZ (1) CZ2002531A3 (en)
HU (1) HUP0202438A2 (en)
IL (1) IL148164A0 (en)
MX (1) MXPA02001716A (en)
NO (1) NO20020777L (en)
PL (1) PL353886A1 (en)
TR (1) TR200200438T2 (en)
WO (1) WO2001012628A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040115626A1 (en) * 2000-05-25 2004-06-17 Masahide Goto Human pgc-1 promoter
WO2003029251A1 (en) * 2001-09-28 2003-04-10 Biocon Limited Novel process for the synthesis of thiazolidinedione derivatives
GB0129871D0 (en) * 2001-12-13 2002-02-06 Smithkline Beecham Plc Novel pharmaceutical
GB0130509D0 (en) * 2001-12-20 2002-02-06 Smithkline Beecham Plc Novel pharmaceutical
KR100450700B1 (en) * 2002-03-22 2004-10-01 주식회사종근당 Thiazolidinedione derivatives and pharmaceutical composition comprising the same
KR20050068860A (en) 2003-12-30 2005-07-05 엘지.필립스 엘시디 주식회사 Upper substrate for use in dual-plate organic electroluminescent device and method for fabricating the same

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0842925A1 (en) * 1987-09-04 1998-05-20 Beecham Group Plc Substituted thiazolidinedione derivatives
GB8919417D0 (en) * 1989-08-25 1989-10-11 Beecham Group Plc Novel compounds
GB9218830D0 (en) * 1992-09-05 1992-10-21 Smithkline Beecham Plc Novel compounds
SG47100A1 (en) * 1994-02-10 1998-03-20 Smithkline Beecham Plc Use of insulin sensitisers for treating renal diseases

Also Published As

Publication number Publication date
MXPA02001716A (en) 2002-08-06
JP2003507379A (en) 2003-02-25
CZ2002531A3 (en) 2002-07-17
AU7408900A (en) 2001-03-13
KR20020022812A (en) 2002-03-27
EP1202991A1 (en) 2002-05-08
CA2381976A1 (en) 2001-02-22
WO2001012628A1 (en) 2001-02-22
NO20020777D0 (en) 2002-02-15
IL148164A0 (en) 2002-09-12
NO20020777L (en) 2002-02-15
BR0013375A (en) 2002-07-23
CN1379776A (en) 2002-11-13
PL353886A1 (en) 2003-12-01
TR200200438T2 (en) 2002-05-21

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