HUP0201539A3 - Carboxylic acid derivatives that inhibit the binding of integrins to their receptors - Google Patents

Carboxylic acid derivatives that inhibit the binding of integrins to their receptors

Info

Publication number
HUP0201539A3
HUP0201539A3 HU0201539A HUP0201539A HUP0201539A3 HU P0201539 A3 HUP0201539 A3 HU P0201539A3 HU 0201539 A HU0201539 A HU 0201539A HU P0201539 A HUP0201539 A HU P0201539A HU P0201539 A3 HUP0201539 A3 HU P0201539A3
Authority
HU
Hungary
Prior art keywords
integrins
receptors
inhibit
binding
carboxylic acid
Prior art date
Application number
HU0201539A
Other languages
Hungarian (hu)
Original Assignee
Texas Biotechnology Corp Houst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Texas Biotechnology Corp Houst filed Critical Texas Biotechnology Corp Houst
Priority claimed from PCT/US2000/012303 external-priority patent/WO2000067746A1/en
Publication of HUP0201539A2 publication Critical patent/HUP0201539A2/en
Publication of HUP0201539A3 publication Critical patent/HUP0201539A3/en
Publication of HU229307B1 publication Critical patent/HU229307B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/47—One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
HU0201539A 1999-05-07 2000-05-05 Carboxylic acid derivatives that inhibit the binding of integrins to their receptors HU229307B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13219799P 1999-05-07 1999-05-07
PCT/US2000/012303 WO2000067746A1 (en) 1999-05-07 2000-05-05 Carboxylic acid derivatives that inhibit the binding of integrins to their receptors

Publications (3)

Publication Number Publication Date
HUP0201539A2 HUP0201539A2 (en) 2002-08-28
HUP0201539A3 true HUP0201539A3 (en) 2003-07-28
HU229307B1 HU229307B1 (en) 2013-10-28

Family

ID=22452921

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0201539A HU229307B1 (en) 1999-05-07 2000-05-05 Carboxylic acid derivatives that inhibit the binding of integrins to their receptors

Country Status (5)

Country Link
KR (1) KR100853950B1 (en)
CN (1) CN1292744C (en)
BR (1) BR0010293B1 (en)
HU (1) HU229307B1 (en)
PT (1) PT1176956E (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8586604B2 (en) * 2010-08-20 2013-11-19 Boehringer Ingelheim International Gmbh Inhibitors of the microsomal prostaglandin E2 synthase-1

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5770573A (en) * 1993-12-06 1998-06-23 Cytel Corporation CS-1 peptidomimetics, compositions and methods of using the same

Also Published As

Publication number Publication date
BR0010293B1 (en) 2011-09-20
HUP0201539A2 (en) 2002-08-28
BR0010293A (en) 2002-07-16
HU229307B1 (en) 2013-10-28
KR100853950B1 (en) 2008-08-25
CN1360498A (en) 2002-07-24
KR20020009607A (en) 2002-02-01
PT1176956E (en) 2008-04-17
CN1292744C (en) 2007-01-03

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Legal Events

Date Code Title Description
FD9A Lapse of provisional protection due to non-payment of fees
NF4A Restoration of patent protection
HC9A Change of name, address

Owner name: ENCYSIVE PHARMACEUTICALS INC., US

Free format text: FORMER OWNER(S): TEXAS BIOTECHNOLOGY CORPORATION, US

TH4A Erratum
MM4A Lapse of definitive patent protection due to non-payment of fees