HUP0201117A2 - Attenuated microorganisms for the treatment of infection - Google Patents

Attenuated microorganisms for the treatment of infection

Info

Publication number
HUP0201117A2
HUP0201117A2 HU0201117A HUP0201117A HUP0201117A2 HU P0201117 A2 HUP0201117 A2 HU P0201117A2 HU 0201117 A HU0201117 A HU 0201117A HU P0201117 A HUP0201117 A HU P0201117A HU P0201117 A2 HUP0201117 A2 HU P0201117A2
Authority
HU
Hungary
Prior art keywords
infection
treatment
attenuated microorganisms
attenuated
microorganisms
Prior art date
Application number
HU0201117A
Other languages
Hungarian (hu)
Inventor
Gordon Dougan
Zoe Hindle
David William Holden
Joseph David Santangelo
Jacqueline Elizabeth Shea
Original Assignee
Microscience Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Microscience Ltd filed Critical Microscience Ltd
Publication of HUP0201117A2 publication Critical patent/HUP0201117A2/en
Publication of HUP0201117A3 publication Critical patent/HUP0201117A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K14/255—Salmonella (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K2035/11—Medicinal preparations comprising living procariotic cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/522—Bacterial cells; Fungal cells; Protozoal cells avirulent or attenuated
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/42—Salmonella
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
HU0201117A 1999-05-10 2000-05-09 Attenuated microorganisms for the treatment of infection HUP0201117A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9910812.8A GB9910812D0 (en) 1999-05-10 1999-05-10 Vaccine composition

Publications (2)

Publication Number Publication Date
HUP0201117A2 true HUP0201117A2 (en) 2002-08-28
HUP0201117A3 HUP0201117A3 (en) 2004-01-28

Family

ID=10853168

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0201117A HUP0201117A3 (en) 1999-05-10 2000-05-09 Attenuated microorganisms for the treatment of infection

Country Status (28)

Country Link
US (3) US6756042B1 (en)
EP (2) EP1702927B1 (en)
JP (1) JP4583607B2 (en)
KR (2) KR100680391B1 (en)
CN (1) CN1177863C (en)
AP (1) AP1470A (en)
AT (2) ATE346090T1 (en)
AU (1) AU763898B2 (en)
BR (1) BRPI0010418B8 (en)
CA (1) CA2372553C (en)
CY (1) CY1107656T1 (en)
CZ (1) CZ301926B6 (en)
DE (2) DE60031974T2 (en)
DK (1) DK1183269T3 (en)
EA (1) EA004921B1 (en)
ES (1) ES2277591T3 (en)
GB (1) GB9910812D0 (en)
HU (1) HUP0201117A3 (en)
IL (3) IL146255A0 (en)
MA (1) MA25411A1 (en)
MX (1) MXPA01011477A (en)
NO (1) NO329520B1 (en)
NZ (1) NZ539260A (en)
OA (1) OA11940A (en)
PT (1) PT1183269E (en)
TR (1) TR200702949T2 (en)
WO (1) WO2000068261A2 (en)
ZA (1) ZA200108912B (en)

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GB9910812D0 (en) * 1999-05-10 1999-07-07 Microscience Ltd Vaccine composition
GB0105924D0 (en) * 2001-03-09 2001-04-25 Microscience Ltd Promoter
US7449178B2 (en) * 2002-04-05 2008-11-11 Merial Limited Attenuated gram negative bacteria
US20080124355A1 (en) 2006-09-22 2008-05-29 David Gordon Bermudes Live bacterial vaccines for viral infection prophylaxis or treatment
US20110027321A1 (en) * 2007-05-25 2011-02-03 Emergent Product Development Gaithersburg Inc. Chlamydia Vaccine Comprising HtrA Polypeptides
EP2326344A4 (en) * 2008-06-16 2013-08-07 Prokarium Ltd Salmonella vectored vaccines against chlamydia and methods of use
WO2010017383A1 (en) 2008-08-06 2010-02-11 Emergent Product Development Uk Limited Vaccines against clostridium difficile and methods of use
WO2010048322A1 (en) * 2008-10-21 2010-04-29 Emergent Product Development United Kingdom Use of e. coli surface antigen 3 sequences for the export of heterologous antigens
US8481052B2 (en) 2011-05-17 2013-07-09 Cj Cheiljedang Corporation Avirulent Salmonella gallinarum variants and pharmaceutical composition using the same
WO2015052350A2 (en) 2013-10-11 2015-04-16 Servicio Galego De Saúde (Sergas) Live attenuated vaccines
US9616114B1 (en) 2014-09-18 2017-04-11 David Gordon Bermudes Modified bacteria having improved pharmacokinetics and tumor colonization enhancing antitumor activity
US11129906B1 (en) 2016-12-07 2021-09-28 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
US11180535B1 (en) 2016-12-07 2021-11-23 David Gordon Bermudes Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria
US11541105B2 (en) 2018-06-01 2023-01-03 The Research Foundation For The State University Of New York Compositions and methods for disrupting biofilm formation and maintenance
US11471497B1 (en) 2019-03-13 2022-10-18 David Gordon Bermudes Copper chelation therapeutics
US10973908B1 (en) 2020-05-14 2021-04-13 David Gordon Bermudes Expression of SARS-CoV-2 spike protein receptor binding domain in attenuated salmonella as a vaccine
EP3922255A1 (en) 2020-06-10 2021-12-15 Prokarium Limited Cancer therapy
EP4124342A1 (en) 2021-07-28 2023-02-01 Prokarium Limited Cancer therapy with live attenuated bacteria
WO2023105076A1 (en) 2021-12-09 2023-06-15 Prokarium Limited Combination cancer therapy
WO2024061748A1 (en) 2022-09-21 2024-03-28 Prokarium Limited Salmonella strain with chromosomally integrated landing pad

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Also Published As

Publication number Publication date
IL146255A (en) 2008-11-26
AP2001002317A0 (en) 2001-12-31
MXPA01011477A (en) 2002-06-04
CZ20014030A3 (en) 2002-06-12
EP1702927B1 (en) 2010-02-17
PT1183269E (en) 2007-02-28
HUP0201117A3 (en) 2004-01-28
CZ301926B6 (en) 2010-08-04
AP1470A (en) 2005-09-26
WO2000068261A2 (en) 2000-11-16
ATE457998T1 (en) 2010-03-15
EA004921B1 (en) 2004-10-28
US7887816B2 (en) 2011-02-15
AU4593200A (en) 2000-11-21
DE60031974T2 (en) 2007-03-15
NO20015464D0 (en) 2001-11-08
NO329520B1 (en) 2010-11-01
IL146255A0 (en) 2002-07-25
KR100680391B1 (en) 2007-02-08
EA200101187A1 (en) 2002-04-25
US6756042B1 (en) 2004-06-29
TR200702949T2 (en) 2007-08-21
ATE346090T1 (en) 2006-12-15
NZ539260A (en) 2007-01-26
IL186993A (en) 2010-02-17
KR20020018193A (en) 2002-03-07
JP2003509008A (en) 2003-03-11
ES2277591T3 (en) 2007-07-16
KR20060101563A (en) 2006-09-25
PL354355A1 (en) 2004-01-12
BR0010418B1 (en) 2013-04-16
CA2372553C (en) 2011-09-27
MA25411A1 (en) 2002-04-01
GB9910812D0 (en) 1999-07-07
EP1183269B1 (en) 2006-11-22
CN1177863C (en) 2004-12-01
KR100811319B1 (en) 2008-03-07
CY1107656T1 (en) 2013-04-18
US20040191866A1 (en) 2004-09-30
US7211264B2 (en) 2007-05-01
DE60031974D1 (en) 2007-01-04
DK1183269T3 (en) 2007-04-02
CA2372553A1 (en) 2000-11-16
OA11940A (en) 2006-04-12
WO2000068261A3 (en) 2001-02-08
BRPI0010418B8 (en) 2021-05-25
EP1183269A1 (en) 2002-03-06
BR0010418A (en) 2003-07-22
ZA200108912B (en) 2002-12-24
NO20015464L (en) 2001-11-08
JP4583607B2 (en) 2010-11-17
AU763898B2 (en) 2003-07-31
CN1360594A (en) 2002-07-24
EP1702927A1 (en) 2006-09-20
US20080274139A1 (en) 2008-11-06
DE60043868D1 (en) 2010-04-01

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Legal Events

Date Code Title Description
FC4A Lapse of provisional application due to refusal