HUP0200345A2 - Novel nucleic acid transferring agents, compositions containing them and uses - Google Patents
Novel nucleic acid transferring agents, compositions containing them and usesInfo
- Publication number
- HUP0200345A2 HUP0200345A2 HU0200345A HUP0200345A HUP0200345A2 HU P0200345 A2 HUP0200345 A2 HU P0200345A2 HU 0200345 A HU0200345 A HU 0200345A HU P0200345 A HUP0200345 A HU P0200345A HU P0200345 A2 HUP0200345 A2 HU P0200345A2
- Authority
- HU
- Hungary
- Prior art keywords
- nucleic acid
- compositions containing
- novel nucleic
- transferring agents
- acid transferring
- Prior art date
Links
- 239000003795 chemical substances by application Substances 0.000 title abstract 3
- 150000007523 nucleic acids Chemical class 0.000 title abstract 3
- 102000039446 nucleic acids Human genes 0.000 title abstract 3
- 108020004707 nucleic acids Proteins 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 title 1
- 230000002209 hydrophobic effect Effects 0.000 abstract 1
- 238000000338 in vitro Methods 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/02—Acyclic radicals, not substituted by cyclic structures
- C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
Abstract
A találmány tárgyát új transzferáló ágensek, azokat tartalmazókészítmények, és a nukleinsavaknak sejtekbe történő in vitro, in vivoés ex vivo transzferálására való alkalmazásuk képezik. Pontosabban, atalálmány olyan új nukleinsav-transzferáló ágensekre vonatkozik,amelyek egy - egyrészt egy polikationhoz, másrészt legalább egyhidrofil szubsztituenshez kémiailag kapcsolódó - hidrofób kapcsottartalmaznak. ÓThe subject of the invention is new transfer agents, preparations containing them, and their use for in vitro, in vivo and ex vivo transfer of nucleic acids into cells. More specifically, the invention relates to new nucleic acid transfer agents that contain a hydrophobic link chemically linked to a polycation on the one hand and at least one hydrophilic substituent on the other. HE
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9815309A FR2786700B1 (en) | 1998-12-03 | 1998-12-03 | NOVEL NUCLEIC ACID TRANSFERS, COMPOSITIONS CONTAINING THEM, AND USES THEREOF |
| US11718499P | 1999-01-26 | 1999-01-26 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HUP0200345A2 true HUP0200345A2 (en) | 2002-05-29 |
| HUP0200345A3 HUP0200345A3 (en) | 2003-12-29 |
Family
ID=26234691
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU0200345A HUP0200345A3 (en) | 1998-12-03 | 1999-12-02 | Novel nucleic acid transferring agents, compositions containing them and uses |
Country Status (13)
| Country | Link |
|---|---|
| EP (1) | EP1137793A2 (en) |
| JP (1) | JP2002531468A (en) |
| KR (1) | KR20010101116A (en) |
| CN (1) | CN1348498A (en) |
| AU (1) | AU772033B2 (en) |
| BR (1) | BR9915897A (en) |
| CA (1) | CA2353576A1 (en) |
| CZ (1) | CZ20011909A3 (en) |
| HU (1) | HUP0200345A3 (en) |
| IL (1) | IL142704A0 (en) |
| NO (1) | NO20012684L (en) |
| PL (1) | PL348513A1 (en) |
| WO (1) | WO2000032803A2 (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2805271B1 (en) * | 2000-02-18 | 2002-04-26 | Aventis Pharma Sa | PROCESS FOR THE PREPARATION OF FUNCTIONALIZED POLYALKYLENIMINES, COMPOSITIONS CONTAINING THEM AND USES THEREOF |
| JP2005080598A (en) * | 2003-09-10 | 2005-03-31 | Japan Science & Technology Agency | METHOD FOR INTRODUCING PLASMID DNA BY USING beta-1,3-GLUCAN DERIVATIVE |
| CN103820320B (en) * | 2013-06-25 | 2017-03-15 | 宁波有成生物医药科技有限公司 | Liquid protected by a kind of non-jelly type RNA |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1996021036A2 (en) * | 1994-12-30 | 1996-07-11 | Chiron Viagene, Inc. | Nucleic acid condensing agents with reduced immunogenicity |
| FR2730637B1 (en) * | 1995-02-17 | 1997-03-28 | Rhone Poulenc Rorer Sa | PHARMACEUTICAL COMPOSITION CONTAINING NUCLEIC ACIDS, AND USES THEREOF |
| US5948681A (en) * | 1996-08-14 | 1999-09-07 | Children's Hospital Of Philadelphia | Non-viral vehicles for use in gene transfer |
-
1999
- 1999-12-02 HU HU0200345A patent/HUP0200345A3/en unknown
- 1999-12-02 EP EP99958234A patent/EP1137793A2/en not_active Withdrawn
- 1999-12-02 BR BR9915897-3A patent/BR9915897A/en not_active IP Right Cessation
- 1999-12-02 AU AU15646/00A patent/AU772033B2/en not_active Ceased
- 1999-12-02 WO PCT/FR1999/002995 patent/WO2000032803A2/en not_active Application Discontinuation
- 1999-12-02 JP JP2000585434A patent/JP2002531468A/en not_active Withdrawn
- 1999-12-02 CN CN99813646A patent/CN1348498A/en active Pending
- 1999-12-02 KR KR1020017006897A patent/KR20010101116A/en not_active Application Discontinuation
- 1999-12-02 CZ CZ20011909A patent/CZ20011909A3/en unknown
- 1999-12-02 IL IL14270499A patent/IL142704A0/en unknown
- 1999-12-02 PL PL99348513A patent/PL348513A1/en not_active Application Discontinuation
- 1999-12-02 CA CA002353576A patent/CA2353576A1/en not_active Abandoned
-
2001
- 2001-05-31 NO NO20012684A patent/NO20012684L/en not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| WO2000032803A3 (en) | 2000-10-12 |
| EP1137793A2 (en) | 2001-10-04 |
| NO20012684D0 (en) | 2001-05-31 |
| IL142704A0 (en) | 2002-03-10 |
| PL348513A1 (en) | 2002-06-03 |
| KR20010101116A (en) | 2001-11-14 |
| JP2002531468A (en) | 2002-09-24 |
| HUP0200345A3 (en) | 2003-12-29 |
| AU1564600A (en) | 2000-06-19 |
| CN1348498A (en) | 2002-05-08 |
| BR9915897A (en) | 2001-08-21 |
| NO20012684L (en) | 2001-07-30 |
| CZ20011909A3 (en) | 2001-09-12 |
| CA2353576A1 (en) | 2000-06-08 |
| AU772033B2 (en) | 2004-04-08 |
| WO2000032803A2 (en) | 2000-06-08 |
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