HUP0102479A2 - Basbo29 polynucleotides(s) and polypeptides from neisseria meningitidis - Google Patents
Basbo29 polynucleotides(s) and polypeptides from neisseria meningitidisInfo
- Publication number
- HUP0102479A2 HUP0102479A2 HU0102479A HUP0102479A HUP0102479A2 HU P0102479 A2 HUP0102479 A2 HU P0102479A2 HU 0102479 A HU0102479 A HU 0102479A HU P0102479 A HUP0102479 A HU P0102479A HU P0102479 A2 HUP0102479 A2 HU P0102479A2
- Authority
- HU
- Hungary
- Prior art keywords
- neisseria meningitidis
- polypeptides
- basbo29
- polynucleotides
- treatment
- Prior art date
Links
- 241000588650 Neisseria meningitidis Species 0.000 title abstract 3
- 229920001184 polypeptide Polymers 0.000 title abstract 3
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 3
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 3
- 102000040430 polynucleotide Human genes 0.000 title abstract 2
- 108091033319 polynucleotide Proteins 0.000 title abstract 2
- 239000002157 polynucleotide Substances 0.000 title abstract 2
- 201000010099 disease Diseases 0.000 abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 238000003745 diagnosis Methods 0.000 abstract 1
- 239000013604 expression vector Substances 0.000 abstract 1
- 244000005700 microbiome Species 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
- 229960005486 vaccine Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
- C07K16/1203—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria
- C07K16/1217—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria from Neisseriaceae (F)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/22—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Neisseriaceae (F)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56911—Bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
- C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
Abstract
A találmány tárgyát képezik izolált BASB020 polipeptidek, ellenükkészült antitestek, továbbá a polipeptideket kódoló izoláltpolinukleotidok, az azokat tartalmazó expressziós vektorok és élőmikroorganizmusok, továbbá Neisseria meningitidis betegségben szenvedőemberi személyek kezelésére alkalmas terápiás készítmények ésoltóanyagok, valamint alkalmazásuk. A találmány szerinti megoldáselsősorban Neisseria meningitidis okozta betegségekdiagnosztizálásában, megelőzésében és kezelésében alkalmazható. ÓThe subject of the invention are isolated BASB020 polypeptides, antibodies prepared against them, isolated polynucleotides encoding polypeptides, expression vectors and live microorganisms containing them, therapeutic preparations and vaccines suitable for the treatment of human subjects suffering from Neisseria meningitidis disease, and their use. The solution according to the invention can primarily be used in the diagnosis, prevention and treatment of diseases caused by Neisseria meningitidis. HE
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9810276.7A GB9810276D0 (en) | 1998-05-13 | 1998-05-13 | Novel compounds |
PCT/EP1999/003255 WO1999058683A2 (en) | 1998-05-13 | 1999-05-07 | BASB029 POLYNUCLEOTIDE(S) AND POLYPEPTIDES FROM $i(NEISSERIA MENINGITIDIS) |
Publications (2)
Publication Number | Publication Date |
---|---|
HUP0102479A2 true HUP0102479A2 (en) | 2001-10-28 |
HUP0102479A3 HUP0102479A3 (en) | 2004-10-28 |
Family
ID=10831992
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU0102479A HUP0102479A3 (en) | 1998-05-13 | 1999-05-07 | Basbo29 polynucleotides(s) and polypeptides from neisseria meningitidis |
Country Status (24)
Country | Link |
---|---|
US (3) | US6780419B1 (en) |
EP (2) | EP1621623A3 (en) |
JP (2) | JP4707832B2 (en) |
KR (4) | KR20100019461A (en) |
CN (1) | CN1322127C (en) |
AT (1) | ATE311457T1 (en) |
AU (1) | AU750032B2 (en) |
BR (1) | BR9910396A (en) |
CA (1) | CA2328403C (en) |
CY (1) | CY1105676T1 (en) |
CZ (1) | CZ299612B6 (en) |
DE (1) | DE69928658T2 (en) |
DK (1) | DK1078063T3 (en) |
ES (1) | ES2252946T3 (en) |
GB (1) | GB9810276D0 (en) |
HK (1) | HK1036300A1 (en) |
HU (1) | HUP0102479A3 (en) |
IL (2) | IL139613A0 (en) |
NO (2) | NO326994B1 (en) |
NZ (1) | NZ508323A (en) |
PL (1) | PL197449B1 (en) |
TR (1) | TR200003347T2 (en) |
WO (1) | WO1999058683A2 (en) |
ZA (1) | ZA200006523B (en) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9726398D0 (en) * | 1997-12-12 | 1998-02-11 | Isis Innovation | Polypeptide and coding sequences |
WO1999036544A2 (en) * | 1998-01-14 | 1999-07-22 | Chiron S.P.A. | Neisseria meningitidis antigens |
GB9810276D0 (en) * | 1998-05-13 | 1998-07-15 | Smithkline Beecham Biolog | Novel compounds |
CA2371994C (en) | 1999-02-26 | 2010-09-28 | Guido Grandi | Enhancement of bactericidal activity of neisseria antigens with oligonucleotides containing cg motifs |
GB9916529D0 (en) * | 1999-07-14 | 1999-09-15 | Chiron Spa | Antigenic peptides |
PT2275551E (en) | 1999-10-29 | 2015-06-29 | Novartis Vaccines & Diagnostic | Neisserial antigenic peptides |
GB9928196D0 (en) | 1999-11-29 | 2000-01-26 | Chiron Spa | Combinations of B, C and other antigens |
MXPA02006962A (en) * | 2000-01-17 | 2002-12-13 | Chiron Spa | Outer membrane vesicle (omv) vaccine comprising n. meningitidis serogroup b outer membrane proteins. |
US7947291B2 (en) * | 2000-01-25 | 2011-05-24 | The University Of Queensland | Modified surface antigen |
CN100334214C (en) | 2000-02-28 | 2007-08-29 | 启龙股份公司 | Hybrid expression of Neisseria protein |
JP4592284B2 (en) | 2001-07-27 | 2010-12-01 | カイロン ソチエタ ア レスポンサビリタ リミタータ | Neisseria meningitidis attachment factor |
EP1961427A3 (en) | 2002-08-02 | 2009-11-04 | GlaxoSmithKline Biologicals S.A. | Neisserial vaccine compositions comprising a combination of antigens |
SI2351579T1 (en) | 2002-10-11 | 2017-05-31 | Glaxosmithkline Biologicals Sa | Polypeptide vaccines for broad protection against hypervirulent meningococcal lineages |
CN103405761A (en) | 2003-10-02 | 2013-11-27 | 诺华疫苗和诊断有限公司 | Liquid vaccines for multiple meningococcal serogroups |
US7459930B2 (en) * | 2006-11-14 | 2008-12-02 | Micron Technology, Inc. | Digital calibration circuits, devices and systems including same, and methods of operation |
GB0700562D0 (en) | 2007-01-11 | 2007-02-21 | Novartis Vaccines & Diagnostic | Modified Saccharides |
GB0916570D0 (en) | 2009-09-21 | 2009-10-28 | Royal Holloway & Bedford New C | Method |
US9365624B2 (en) | 2010-03-11 | 2016-06-14 | Glaxosmithkline Biologicals, S.A. | Vaccine |
JP6316755B2 (en) * | 2012-01-05 | 2018-04-25 | ドイチェス クレープスフォルシュングスツェントルムDeutsches Krebsforschungszentrum | Means and methods for treating or diagnosing IDH1R132H mutation-positive cancer |
BR112019001456B1 (en) | 2016-07-27 | 2022-12-13 | Prysmian S.P.A | FLEXIBLE FIBER OPTICAL TAPE |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4769240A (en) * | 1980-09-15 | 1988-09-06 | Bactex, Inc. | Pili of neisseria and vaccine compositions containing same |
US4702911A (en) * | 1985-09-27 | 1987-10-27 | Immunomed Corporation | Preparation of bacterium pili subunits and vaccines containing pili subunits |
JPH01125328A (en) * | 1987-07-30 | 1989-05-17 | Centro Natl De Biopreparados | Meningococcus vaccine |
FR2682041B1 (en) * | 1991-10-03 | 1994-01-14 | Pasteur Merieux Serums Vaccins | VACCINE AGAINST NEISSERIA MENINGITIDIS INFECTIONS. |
US6245337B1 (en) * | 1994-08-25 | 2001-06-12 | Washington University | Haemophilus adherence and penetration proteins |
US6121037A (en) * | 1994-10-18 | 2000-09-19 | Stojiljkovic; Igor | Bacterial hemoglobin receptor genes |
US5646259A (en) * | 1995-03-24 | 1997-07-08 | St. Louis University | DNA encoding haemophilus adhesion proteins |
US6265567B1 (en) * | 1995-04-07 | 2001-07-24 | University Of North Carolina At Chapel Hill | Isolated FrpB nucleic acid molecule |
CU22559A1 (en) | 1996-01-17 | 1999-05-03 | Ct Ingenieria Genetica Biotech | EXPRESSION SYSTEM OF HETEROLOGICAL ANTIGENS IN E. COLI AS FUSION PROTEINS |
GB9726398D0 (en) * | 1997-12-12 | 1998-02-11 | Isis Innovation | Polypeptide and coding sequences |
WO1999036544A2 (en) * | 1998-01-14 | 1999-07-22 | Chiron S.P.A. | Neisseria meningitidis antigens |
GB9810276D0 (en) * | 1998-05-13 | 1998-07-15 | Smithkline Beecham Biolog | Novel compounds |
WO2000066741A2 (en) * | 1999-04-30 | 2000-11-09 | Chiron S.P.A. | Conserved neisserial antigens |
-
1998
- 1998-05-13 GB GBGB9810276.7A patent/GB9810276D0/en not_active Ceased
-
1999
- 1999-05-07 BR BR9910396-6A patent/BR9910396A/en not_active Application Discontinuation
- 1999-05-07 KR KR1020097024661A patent/KR20100019461A/en not_active Application Discontinuation
- 1999-05-07 AU AU41420/99A patent/AU750032B2/en not_active Ceased
- 1999-05-07 DK DK99924946T patent/DK1078063T3/en active
- 1999-05-07 DE DE69928658T patent/DE69928658T2/en not_active Expired - Lifetime
- 1999-05-07 PL PL345281A patent/PL197449B1/en not_active IP Right Cessation
- 1999-05-07 CA CA2328403A patent/CA2328403C/en not_active Expired - Fee Related
- 1999-05-07 NZ NZ508323A patent/NZ508323A/en not_active IP Right Cessation
- 1999-05-07 CN CNB998086061A patent/CN1322127C/en not_active Expired - Fee Related
- 1999-05-07 CZ CZ20004202A patent/CZ299612B6/en not_active IP Right Cessation
- 1999-05-07 ES ES99924946T patent/ES2252946T3/en not_active Expired - Lifetime
- 1999-05-07 TR TR2000/03347T patent/TR200003347T2/en unknown
- 1999-05-07 KR KR1020087014761A patent/KR20080070073A/en active Application Filing
- 1999-05-07 WO PCT/EP1999/003255 patent/WO1999058683A2/en active IP Right Grant
- 1999-05-07 IL IL13961399A patent/IL139613A0/en unknown
- 1999-05-07 HU HU0102479A patent/HUP0102479A3/en unknown
- 1999-05-07 KR KR1020067009829A patent/KR100897951B1/en not_active IP Right Cessation
- 1999-05-07 EP EP20050077297 patent/EP1621623A3/en not_active Withdrawn
- 1999-05-07 JP JP2000548474A patent/JP4707832B2/en not_active Expired - Fee Related
- 1999-05-07 AT AT99924946T patent/ATE311457T1/en active
- 1999-05-07 US US09/700,293 patent/US6780419B1/en not_active Expired - Lifetime
- 1999-05-07 EP EP99924946A patent/EP1078063B1/en not_active Expired - Lifetime
- 1999-05-07 KR KR1020007012700A patent/KR100673674B1/en not_active IP Right Cessation
-
2000
- 2000-11-10 ZA ZA200006523A patent/ZA200006523B/en unknown
- 2000-11-10 IL IL139613A patent/IL139613A/en not_active IP Right Cessation
- 2000-11-10 NO NO20005696A patent/NO326994B1/en not_active IP Right Cessation
-
2001
- 2001-08-13 HK HK01105651A patent/HK1036300A1/en not_active IP Right Cessation
-
2004
- 2004-07-22 US US10/896,778 patent/US20040265332A1/en not_active Abandoned
-
2006
- 2006-01-17 CY CY20061100057T patent/CY1105676T1/en unknown
-
2007
- 2007-12-07 US US11/999,978 patent/US20090093622A1/en not_active Abandoned
-
2009
- 2009-03-02 NO NO20090955A patent/NO20090955L/en not_active Application Discontinuation
-
2010
- 2010-03-01 JP JP2010044336A patent/JP2010166921A/en active Pending
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD9A | Lapse of provisional protection due to non-payment of fees |