HUP0102479A2 - Basbo29 polynucleotides(s) and polypeptides from neisseria meningitidis - Google Patents

Basbo29 polynucleotides(s) and polypeptides from neisseria meningitidis

Info

Publication number
HUP0102479A2
HUP0102479A2 HU0102479A HUP0102479A HUP0102479A2 HU P0102479 A2 HUP0102479 A2 HU P0102479A2 HU 0102479 A HU0102479 A HU 0102479A HU P0102479 A HUP0102479 A HU P0102479A HU P0102479 A2 HUP0102479 A2 HU P0102479A2
Authority
HU
Hungary
Prior art keywords
neisseria meningitidis
polypeptides
basbo29
polynucleotides
treatment
Prior art date
Application number
HU0102479A
Other languages
Hungarian (hu)
Inventor
Jean-Louis Ruelle
Original Assignee
Smithkline Beecham Biologicals S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10831992&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HUP0102479(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Smithkline Beecham Biologicals S.A. filed Critical Smithkline Beecham Biologicals S.A.
Publication of HUP0102479A2 publication Critical patent/HUP0102479A2/en
Publication of HUP0102479A3 publication Critical patent/HUP0102479A3/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1203Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria
    • C07K16/1217Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria from Neisseriaceae (F)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/22Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Neisseriaceae (F)
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911Bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53DNA (RNA) vaccination
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria

Abstract

A találmány tárgyát képezik izolált BASB020 polipeptidek, ellenükkészült antitestek, továbbá a polipeptideket kódoló izoláltpolinukleotidok, az azokat tartalmazó expressziós vektorok és élőmikroorganizmusok, továbbá Neisseria meningitidis betegségben szenvedőemberi személyek kezelésére alkalmas terápiás készítmények ésoltóanyagok, valamint alkalmazásuk. A találmány szerinti megoldáselsősorban Neisseria meningitidis okozta betegségekdiagnosztizálásában, megelőzésében és kezelésében alkalmazható. ÓThe subject of the invention are isolated BASB020 polypeptides, antibodies prepared against them, isolated polynucleotides encoding polypeptides, expression vectors and live microorganisms containing them, therapeutic preparations and vaccines suitable for the treatment of human subjects suffering from Neisseria meningitidis disease, and their use. The solution according to the invention can primarily be used in the diagnosis, prevention and treatment of diseases caused by Neisseria meningitidis. HE

HU0102479A 1998-05-13 1999-05-07 Basbo29 polynucleotides(s) and polypeptides from neisseria meningitidis HUP0102479A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9810276.7A GB9810276D0 (en) 1998-05-13 1998-05-13 Novel compounds
PCT/EP1999/003255 WO1999058683A2 (en) 1998-05-13 1999-05-07 BASB029 POLYNUCLEOTIDE(S) AND POLYPEPTIDES FROM $i(NEISSERIA MENINGITIDIS)

Publications (2)

Publication Number Publication Date
HUP0102479A2 true HUP0102479A2 (en) 2001-10-28
HUP0102479A3 HUP0102479A3 (en) 2004-10-28

Family

ID=10831992

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0102479A HUP0102479A3 (en) 1998-05-13 1999-05-07 Basbo29 polynucleotides(s) and polypeptides from neisseria meningitidis

Country Status (24)

Country Link
US (3) US6780419B1 (en)
EP (2) EP1621623A3 (en)
JP (2) JP4707832B2 (en)
KR (4) KR20100019461A (en)
CN (1) CN1322127C (en)
AT (1) ATE311457T1 (en)
AU (1) AU750032B2 (en)
BR (1) BR9910396A (en)
CA (1) CA2328403C (en)
CY (1) CY1105676T1 (en)
CZ (1) CZ299612B6 (en)
DE (1) DE69928658T2 (en)
DK (1) DK1078063T3 (en)
ES (1) ES2252946T3 (en)
GB (1) GB9810276D0 (en)
HK (1) HK1036300A1 (en)
HU (1) HUP0102479A3 (en)
IL (2) IL139613A0 (en)
NO (2) NO326994B1 (en)
NZ (1) NZ508323A (en)
PL (1) PL197449B1 (en)
TR (1) TR200003347T2 (en)
WO (1) WO1999058683A2 (en)
ZA (1) ZA200006523B (en)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9726398D0 (en) * 1997-12-12 1998-02-11 Isis Innovation Polypeptide and coding sequences
WO1999036544A2 (en) * 1998-01-14 1999-07-22 Chiron S.P.A. Neisseria meningitidis antigens
GB9810276D0 (en) * 1998-05-13 1998-07-15 Smithkline Beecham Biolog Novel compounds
CA2371994C (en) 1999-02-26 2010-09-28 Guido Grandi Enhancement of bactericidal activity of neisseria antigens with oligonucleotides containing cg motifs
GB9916529D0 (en) * 1999-07-14 1999-09-15 Chiron Spa Antigenic peptides
PT2275551E (en) 1999-10-29 2015-06-29 Novartis Vaccines & Diagnostic Neisserial antigenic peptides
GB9928196D0 (en) 1999-11-29 2000-01-26 Chiron Spa Combinations of B, C and other antigens
MXPA02006962A (en) * 2000-01-17 2002-12-13 Chiron Spa Outer membrane vesicle (omv) vaccine comprising n. meningitidis serogroup b outer membrane proteins.
US7947291B2 (en) * 2000-01-25 2011-05-24 The University Of Queensland Modified surface antigen
CN100334214C (en) 2000-02-28 2007-08-29 启龙股份公司 Hybrid expression of Neisseria protein
JP4592284B2 (en) 2001-07-27 2010-12-01 カイロン ソチエタ ア レスポンサビリタ リミタータ Neisseria meningitidis attachment factor
EP1961427A3 (en) 2002-08-02 2009-11-04 GlaxoSmithKline Biologicals S.A. Neisserial vaccine compositions comprising a combination of antigens
SI2351579T1 (en) 2002-10-11 2017-05-31 Glaxosmithkline Biologicals Sa Polypeptide vaccines for broad protection against hypervirulent meningococcal lineages
CN103405761A (en) 2003-10-02 2013-11-27 诺华疫苗和诊断有限公司 Liquid vaccines for multiple meningococcal serogroups
US7459930B2 (en) * 2006-11-14 2008-12-02 Micron Technology, Inc. Digital calibration circuits, devices and systems including same, and methods of operation
GB0700562D0 (en) 2007-01-11 2007-02-21 Novartis Vaccines & Diagnostic Modified Saccharides
GB0916570D0 (en) 2009-09-21 2009-10-28 Royal Holloway & Bedford New C Method
US9365624B2 (en) 2010-03-11 2016-06-14 Glaxosmithkline Biologicals, S.A. Vaccine
JP6316755B2 (en) * 2012-01-05 2018-04-25 ドイチェス クレープスフォルシュングスツェントルムDeutsches Krebsforschungszentrum Means and methods for treating or diagnosing IDH1R132H mutation-positive cancer
BR112019001456B1 (en) 2016-07-27 2022-12-13 Prysmian S.P.A FLEXIBLE FIBER OPTICAL TAPE

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4769240A (en) * 1980-09-15 1988-09-06 Bactex, Inc. Pili of neisseria and vaccine compositions containing same
US4702911A (en) * 1985-09-27 1987-10-27 Immunomed Corporation Preparation of bacterium pili subunits and vaccines containing pili subunits
JPH01125328A (en) * 1987-07-30 1989-05-17 Centro Natl De Biopreparados Meningococcus vaccine
FR2682041B1 (en) * 1991-10-03 1994-01-14 Pasteur Merieux Serums Vaccins VACCINE AGAINST NEISSERIA MENINGITIDIS INFECTIONS.
US6245337B1 (en) * 1994-08-25 2001-06-12 Washington University Haemophilus adherence and penetration proteins
US6121037A (en) * 1994-10-18 2000-09-19 Stojiljkovic; Igor Bacterial hemoglobin receptor genes
US5646259A (en) * 1995-03-24 1997-07-08 St. Louis University DNA encoding haemophilus adhesion proteins
US6265567B1 (en) * 1995-04-07 2001-07-24 University Of North Carolina At Chapel Hill Isolated FrpB nucleic acid molecule
CU22559A1 (en) 1996-01-17 1999-05-03 Ct Ingenieria Genetica Biotech EXPRESSION SYSTEM OF HETEROLOGICAL ANTIGENS IN E. COLI AS FUSION PROTEINS
GB9726398D0 (en) * 1997-12-12 1998-02-11 Isis Innovation Polypeptide and coding sequences
WO1999036544A2 (en) * 1998-01-14 1999-07-22 Chiron S.P.A. Neisseria meningitidis antigens
GB9810276D0 (en) * 1998-05-13 1998-07-15 Smithkline Beecham Biolog Novel compounds
WO2000066741A2 (en) * 1999-04-30 2000-11-09 Chiron S.P.A. Conserved neisserial antigens

Also Published As

Publication number Publication date
AU750032B2 (en) 2002-07-11
KR20060076789A (en) 2006-07-04
AU4142099A (en) 1999-11-29
US6780419B1 (en) 2004-08-24
JP2002514424A (en) 2002-05-21
TR200003347T2 (en) 2001-06-21
PL197449B1 (en) 2008-03-31
DE69928658D1 (en) 2006-01-05
CA2328403A1 (en) 1999-11-18
CZ299612B6 (en) 2008-09-17
EP1621623A2 (en) 2006-02-01
HUP0102479A3 (en) 2004-10-28
CZ20004202A3 (en) 2001-05-16
JP2010166921A (en) 2010-08-05
CN1309707A (en) 2001-08-22
GB9810276D0 (en) 1998-07-15
IL139613A0 (en) 2002-02-10
US20040265332A1 (en) 2004-12-30
WO1999058683A2 (en) 1999-11-18
CY1105676T1 (en) 2010-12-22
EP1621623A3 (en) 2009-02-18
KR20080070073A (en) 2008-07-29
KR100673674B1 (en) 2007-01-23
NO20005696L (en) 2001-01-11
KR20100019461A (en) 2010-02-18
WO1999058683A9 (en) 2002-05-02
HK1036300A1 (en) 2001-12-28
CN1322127C (en) 2007-06-20
EP1078063A2 (en) 2001-02-28
DE69928658T2 (en) 2006-06-14
NO20005696D0 (en) 2000-11-10
PL345281A1 (en) 2001-12-03
ZA200006523B (en) 2001-11-12
NO326994B1 (en) 2009-03-30
DK1078063T3 (en) 2006-04-03
WO1999058683A3 (en) 2000-04-06
EP1078063B1 (en) 2005-11-30
BR9910396A (en) 2001-10-30
JP4707832B2 (en) 2011-06-22
IL139613A (en) 2014-03-31
KR100897951B1 (en) 2009-05-18
CA2328403C (en) 2013-11-05
ES2252946T3 (en) 2006-05-16
US20090093622A1 (en) 2009-04-09
NZ508323A (en) 2002-10-25
NO20090955L (en) 2001-01-11
KR20010043571A (en) 2001-05-25
ATE311457T1 (en) 2005-12-15

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Legal Events

Date Code Title Description
FD9A Lapse of provisional protection due to non-payment of fees