HUP0102297A3 - Process for preparation of 4,5-epoxymorphinan-6-oxi-glucuronides - Google Patents

Process for preparation of 4,5-epoxymorphinan-6-oxi-glucuronides

Info

Publication number
HUP0102297A3
HUP0102297A3 HU0102297A HUP0102297A HUP0102297A3 HU P0102297 A3 HUP0102297 A3 HU P0102297A3 HU 0102297 A HU0102297 A HU 0102297A HU P0102297 A HUP0102297 A HU P0102297A HU P0102297 A3 HUP0102297 A3 HU P0102297A3
Authority
HU
Hungary
Prior art keywords
epoxymorphinan
glucuronides
oxi
preparation
Prior art date
Application number
HU0102297A
Other languages
English (en)
Original Assignee
Cenes Ltd Cambridge
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from IL12446098A external-priority patent/IL124460A0/xx
Application filed by Cenes Ltd Cambridge filed Critical Cenes Ltd Cambridge
Publication of HUP0102297A2 publication Critical patent/HUP0102297A2/hu
Publication of HUP0102297A3 publication Critical patent/HUP0102297A3/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
HU0102297A 1998-05-13 1999-05-12 Process for preparation of 4,5-epoxymorphinan-6-oxi-glucuronides HUP0102297A3 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IL12446098A IL124460A0 (en) 1998-05-13 1998-05-13 Preparation of per-o-acylated alkyl 4,5-epoxymorphinane-6-beta-D-glucuronides
GB9900832 1999-01-15
PCT/GB1999/001508 WO1999058545A1 (en) 1998-05-13 1999-05-12 Process for preparation of 4,5-epoxymorphinan-6-oxyglucuronides

Publications (2)

Publication Number Publication Date
HUP0102297A2 HUP0102297A2 (hu) 2001-10-28
HUP0102297A3 true HUP0102297A3 (en) 2003-07-28

Family

ID=26314988

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0102297A HUP0102297A3 (en) 1998-05-13 1999-05-12 Process for preparation of 4,5-epoxymorphinan-6-oxi-glucuronides

Country Status (9)

Country Link
US (2) US6737518B1 (hu)
EP (1) EP1077985A1 (hu)
JP (1) JP2002514655A (hu)
AU (1) AU761629B2 (hu)
CA (1) CA2331866A1 (hu)
HU (1) HUP0102297A3 (hu)
NO (1) NO20005743L (hu)
PL (1) PL344141A1 (hu)
WO (1) WO1999058545A1 (hu)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2005249508A1 (en) * 2004-05-28 2005-12-15 Human Biomolecular Research Institute Synthesis of metabolically stable analgesics, pain medications and other agents
ITRM20130223A1 (it) * 2013-04-15 2014-10-16 Rosario Nicoletti Derivati della codeina come inibitori della glucuronazione della morfina
CN106008621B (zh) * 2014-03-26 2019-02-19 宜昌人福药业有限责任公司 一种吗啡-6-β-D-葡萄糖醛酸苷的合成方法及其中间体化合物

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9116909D0 (en) * 1991-08-06 1991-09-18 Salford Ultrafine Chem & Res Morphine derivatives
FR2680786B1 (fr) * 1991-09-04 1995-03-10 Irepa Procede de synthese de glucuronides d'epoxy-4,5 morphinanes.

Also Published As

Publication number Publication date
WO1999058545A1 (en) 1999-11-18
US20040053854A1 (en) 2004-03-18
EP1077985A1 (en) 2001-02-28
NO20005743D0 (no) 2000-11-13
AU761629B2 (en) 2003-06-05
CA2331866A1 (en) 1999-11-18
PL344141A1 (en) 2001-10-08
NO20005743L (no) 2001-01-03
HUP0102297A2 (hu) 2001-10-28
US6737518B1 (en) 2004-05-18
AU4050499A (en) 1999-11-29
JP2002514655A (ja) 2002-05-21

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