HUP0101285A2 - Methods and compositions for diagnosis of hepatoma - Google Patents

Methods and compositions for diagnosis of hepatoma

Info

Publication number
HUP0101285A2
HUP0101285A2 HU0101285A HUP0101285A HUP0101285A2 HU P0101285 A2 HUP0101285 A2 HU P0101285A2 HU 0101285 A HU0101285 A HU 0101285A HU P0101285 A HUP0101285 A HU P0101285A HU P0101285 A2 HUP0101285 A2 HU P0101285A2
Authority
HU
Hungary
Prior art keywords
hepatoma
protein isoforms
diagnosis
compositions
methods
Prior art date
Application number
HU0101285A
Other languages
Hungarian (hu)
Inventor
Philip J. Johnson
Christopher Moyses
Rajesh Bhikhu Parekh
Thakorbhai Parshotambhai Patel
Robert Reid Townsend
Original Assignee
Oxford Glycosciences (Uk) Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9803138.8A external-priority patent/GB9803138D0/en
Priority claimed from GBGB9803269.1A external-priority patent/GB9803269D0/en
Application filed by Oxford Glycosciences (Uk) Ltd. filed Critical Oxford Glycosciences (Uk) Ltd.
Publication of HUP0101285A2 publication Critical patent/HUP0101285A2/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57438—Specifically defined cancers of liver, pancreas or kidney
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2550/00—Electrophoretic profiling, e.g. for proteome analysis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Hematology (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

A találmány tárgyát képezi a hepatocelluláris karcinómához (hepatóma)kapcsolódó fehérjék és fehérje izoformák azonosítása, valamint ezekhasználata a szűrővizsgálatban, a diagnosztikában, a prognózisban, aterápiában és a gyógyszerek kifejlesztésében. A szérum vagy plazmakétdimenziós elektroforézisével kimutatható Hepatóma--DiagnosztikaiTulajdonságokat írnak le. A találmány tárgyát képezik a szérumban vagyplazmában kimutatható Hepatóma--Diagnosztikai Fehérje Izoformák, aHepatóma-Diagnosztikai Fehérje Izoformákat tartalmazó készítmények, aHepatóma-Diagnosztikai Fehérje Izoformákra immunspecifikusellenanyagok és az előzőkben említetteket tartalmazó kitek. ÓThe subject of the invention is the identification of proteins and protein isoforms related to hepatocellular carcinoma (hepatoma), as well as their use in screening, diagnostics, prognosis, therapy and drug development. Hepatoma, which can be detected by two-dimensional electrophoresis of serum or plasma, is described. The subject of the invention are Hepatoma Diagnostic Protein Isoforms detectable in serum or plasma, preparations containing Hepatoma Diagnostic Protein Isoforms, immunospecific antibodies to Hepatoma Diagnostic Protein Isoforms and kits containing the aforementioned. HE

HU0101285A 1998-02-13 1999-02-15 Methods and compositions for diagnosis of hepatoma HUP0101285A2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9803138.8A GB9803138D0 (en) 1998-02-13 1998-02-13 Methods and compositions for diagnosis of hepatoma
GBGB9803269.1A GB9803269D0 (en) 1998-02-16 1998-02-16 Methods And Compositions For Diagnosis Of Hepatoma
PCT/GB1999/000458 WO1999041612A1 (en) 1998-02-13 1999-02-15 Methods and compositions for diagnosis of hepatoma

Publications (1)

Publication Number Publication Date
HUP0101285A2 true HUP0101285A2 (en) 2001-08-28

Family

ID=26313117

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0101285A HUP0101285A2 (en) 1998-02-13 1999-02-15 Methods and compositions for diagnosis of hepatoma

Country Status (9)

Country Link
EP (1) EP1055126A1 (en)
JP (1) JP2002503813A (en)
KR (1) KR20010040970A (en)
CN (1) CN1295668A (en)
AU (1) AU2534999A (en)
CA (1) CA2321160A1 (en)
HU (1) HUP0101285A2 (en)
IL (1) IL137836A0 (en)
WO (1) WO1999041612A1 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9919597D0 (en) * 1999-08-18 1999-10-20 Oxford Glycosciences Uk Ltd Methods and compositions for diagnosis of hepatoma
WO2001016603A2 (en) * 1999-09-02 2001-03-08 Proteome Sciences Plc Analysis and treatment of body weight and eating disorders
BR0111742A (en) 2000-06-19 2004-02-03 Correlogic Systems Inc Heuristic Classification Method
EP1386275A2 (en) 2000-07-18 2004-02-04 Correlogic Systems, Inc. A process for discriminating between biological states based on hidden patterns from biological data
AU2002225219A1 (en) * 2001-01-26 2002-08-06 Oxford Glycosciences (Uk) Ltd Diagnosis and treatment of multiple sclerosis
WO2004011905A2 (en) 2002-07-29 2004-02-05 Correlogic Systems, Inc. Quality assurance/quality control for electrospray ionization processes
EP1709442A4 (en) 2003-12-11 2010-01-20 Correlogic Systems Inc Method of diagnosing biological states through the use of a centralized, adaptive model, and remote sample processing
US8664358B2 (en) 2007-06-29 2014-03-04 Vermillion, Inc. Predictive markers for ovarian cancer

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06105257B2 (en) * 1984-08-07 1994-12-21 協和メデックス株式会社 Cancer measurement kit
CA2077322A1 (en) * 1991-09-04 1993-03-05 Allen I. Oliff Peptide inhibitors of human papilloma virus protein binding to retinoblastoma gene proteins
WO1997010333A1 (en) * 1995-09-14 1997-03-20 Sumitomo Electric Industries, Ltd. Novel proteins remarkably expressed in liver cancer, genes encoding the same, antibodies against the same, and method for detecting the expression of the same
JPH09203734A (en) * 1996-01-26 1997-08-05 Sumitomo Electric Ind Ltd Antiserum, antibody, ligand, and method for detecting the same
ATE266203T1 (en) * 1997-06-26 2004-05-15 Univ Michigan METHOD FOR IDENTIFYING TUMOR ANTIGENS WITH AUTOANTIBODIES IN SERUM

Also Published As

Publication number Publication date
EP1055126A1 (en) 2000-11-29
WO1999041612A1 (en) 1999-08-19
JP2002503813A (en) 2002-02-05
AU2534999A (en) 1999-08-30
KR20010040970A (en) 2001-05-15
CN1295668A (en) 2001-05-16
CA2321160A1 (en) 1999-08-19
IL137836A0 (en) 2001-10-31

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