HUP0002979A2 - Terápiásan több célú, ösztrogén agonista és antagonista vegyületek alkalmazása - Google Patents
Terápiásan több célú, ösztrogén agonista és antagonista vegyületek alkalmazásaInfo
- Publication number
- HUP0002979A2 HUP0002979A2 HU0002979A HUP0002979A HUP0002979A2 HU P0002979 A2 HUP0002979 A2 HU P0002979A2 HU 0002979 A HU0002979 A HU 0002979A HU P0002979 A HUP0002979 A HU P0002979A HU P0002979 A2 HUP0002979 A2 HU P0002979A2
- Authority
- HU
- Hungary
- Prior art keywords
- antagonists
- estrogen agonists
- multiple indications
- indications
- lasofoxifene
- Prior art date
Links
- 239000000556 agonist Substances 0.000 title 1
- 239000005557 antagonist Substances 0.000 title 1
- 229940011871 estrogen Drugs 0.000 title 1
- 239000000262 estrogen Substances 0.000 title 1
- AQHHHDLHHXJYJD-UHFFFAOYSA-N propranolol Chemical compound C1=CC=C2C(OCC(O)CNC(C)C)=CC=CC2=C1 AQHHHDLHHXJYJD-UHFFFAOYSA-N 0.000 abstract 2
- 206010006187 Breast cancer Diseases 0.000 abstract 1
- 208000026310 Breast neoplasm Diseases 0.000 abstract 1
- ZQZFYGIXNQKOAV-OCEACIFDSA-N Droloxifene Chemical compound C=1C=CC=CC=1C(/CC)=C(C=1C=C(O)C=CC=1)\C1=CC=C(OCCN(C)C)C=C1 ZQZFYGIXNQKOAV-OCEACIFDSA-N 0.000 abstract 1
- 208000001132 Osteoporosis Diseases 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 229950004203 droloxifene Drugs 0.000 abstract 1
- GXESHMAMLJKROZ-IAPPQJPRSA-N lasofoxifene Chemical compound C1([C@@H]2[C@@H](C3=CC=C(C=C3CC2)O)C=2C=CC(OCCN3CCCC3)=CC=2)=CC=CC=C1 GXESHMAMLJKROZ-IAPPQJPRSA-N 0.000 abstract 1
- 229960002367 lasofoxifene Drugs 0.000 abstract 1
- 229940126601 medicinal product Drugs 0.000 abstract 1
- 230000003449 preventive effect Effects 0.000 abstract 1
- 229960003712 propranolol Drugs 0.000 abstract 1
- PJVWKTKQMONHTI-UHFFFAOYSA-N warfarin Chemical compound OC=1C2=CC=CC=C2OC(=O)C=1C(CC(=O)C)C1=CC=CC=C1 PJVWKTKQMONHTI-UHFFFAOYSA-N 0.000 abstract 1
- 229960005080 warfarin Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/30—Oestrogens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Physical Education & Sports Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Epidemiology (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Vascular Medicine (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Urology & Nephrology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
A tal lm ny t rgya a lazofoxifen és a droloxifen alkalmaz sacsontritkul s, szív- és keringési betegségek és mellr k gyógyító ésmegelőző kezelésére, warfarin és propranolol egyidejű alkalmaz samellett. Ó
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US14607299P | 1999-07-28 | 1999-07-28 | |
US14607599P | 1999-07-28 | 1999-07-28 |
Publications (2)
Publication Number | Publication Date |
---|---|
HU0002979D0 HU0002979D0 (en) | 2000-10-28 |
HUP0002979A2 true HUP0002979A2 (hu) | 2002-04-29 |
Family
ID=26843545
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU0002979A HUP0002979A2 (hu) | 1999-07-28 | 2000-07-27 | Terápiásan több célú, ösztrogén agonista és antagonista vegyületek alkalmazása |
Country Status (9)
Country | Link |
---|---|
EP (1) | EP1086692A3 (hu) |
JP (1) | JP2001048805A (hu) |
KR (1) | KR20010049909A (hu) |
AU (1) | AU4882700A (hu) |
CA (1) | CA2314572A1 (hu) |
HU (1) | HUP0002979A2 (hu) |
IL (1) | IL137428A0 (hu) |
NZ (1) | NZ506014A (hu) |
PE (1) | PE20010347A1 (hu) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6436977B1 (en) * | 1999-09-29 | 2002-08-20 | Pfizer Inc. | Dosing regimens for lasofoxifene |
GB2475907A (en) * | 2009-12-04 | 2011-06-08 | Tcp Innovations Ltd | Composition comprising a mixture of clopidogrel and droloxifene |
SG11201903236SA (en) | 2016-10-11 | 2019-05-30 | Univ Duke | Lasofoxifene treatment of er+ breast cancer |
WO2018071437A1 (en) * | 2016-10-11 | 2018-04-19 | Sermonix Pharmaceuticals, Llc | Lasofoxifene treatment of vva and osteoporosis in survivors of breast cancer and other malignancies |
US11497730B2 (en) | 2018-04-10 | 2022-11-15 | Duke University | Lasofoxifene treatment of breast cancer |
GB202116903D0 (en) | 2021-11-18 | 2022-01-05 | Sermonix Pharmaceuticals Inc | Lasofoxifene treatment of aromatase-resistant er+ cancer |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5552412A (en) * | 1995-01-09 | 1996-09-03 | Pfizer Inc | 5-substitued-6-cyclic-5,6,7,8-tetrahydronaphthalen2-ol compounds which are useful for treating osteoporosis |
-
2000
- 2000-07-03 EP EP00305611A patent/EP1086692A3/en not_active Withdrawn
- 2000-07-20 IL IL13742800A patent/IL137428A0/xx unknown
- 2000-07-21 PE PE2000000737A patent/PE20010347A1/es not_active Application Discontinuation
- 2000-07-24 JP JP2000222159A patent/JP2001048805A/ja active Pending
- 2000-07-25 AU AU48827/00A patent/AU4882700A/en not_active Abandoned
- 2000-07-26 CA CA002314572A patent/CA2314572A1/en not_active Abandoned
- 2000-07-27 KR KR1020000043433A patent/KR20010049909A/ko not_active Application Discontinuation
- 2000-07-27 NZ NZ506014A patent/NZ506014A/en unknown
- 2000-07-27 HU HU0002979A patent/HUP0002979A2/hu unknown
Also Published As
Publication number | Publication date |
---|---|
EP1086692A2 (en) | 2001-03-28 |
EP1086692A3 (en) | 2003-07-09 |
JP2001048805A (ja) | 2001-02-20 |
HU0002979D0 (en) | 2000-10-28 |
CA2314572A1 (en) | 2001-01-28 |
PE20010347A1 (es) | 2001-03-23 |
AU4882700A (en) | 2001-02-01 |
KR20010049909A (ko) | 2001-06-15 |
NZ506014A (en) | 2001-11-30 |
IL137428A0 (en) | 2001-07-24 |
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