HUP0000110A2 - Pharmaceutical compositions comprising azacyclic, azabicyclic or tetrahydro-pyridine-derivatives suitable for treating pain - Google Patents

Pharmaceutical compositions comprising azacyclic, azabicyclic or tetrahydro-pyridine-derivatives suitable for treating pain

Info

Publication number
HUP0000110A2
HUP0000110A2 HU0000110A HUP0000110A HUP0000110A2 HU P0000110 A2 HUP0000110 A2 HU P0000110A2 HU 0000110 A HU0000110 A HU 0000110A HU P0000110 A HUP0000110 A HU P0000110A HU P0000110 A2 HUP0000110 A2 HU P0000110A2
Authority
HU
Hungary
Prior art keywords
azacyclic
azabicyclic
tetrahydro
pyridine
pharmaceutical compositions
Prior art date
Application number
HU0000110A
Other languages
Hungarian (hu)
Inventor
Charles H. Mitch
Harlan E. Shannon
Original Assignee
Eli Lilly And Co.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly And Co. filed Critical Eli Lilly And Co.
Publication of HUP0000110A2 publication Critical patent/HUP0000110A2/en
Publication of HUP0000110A3 publication Critical patent/HUP0000110A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Processing Of Meat And Fish (AREA)

Abstract

A találmány tárgya fájdalőm kezelésére alkalmas gyógyszerkészítmények,melyek a hatóanyagként (I) általánős képletű azaciklűsős,azabiciklűsős vagy tetrahidrőpiridinvegyületeket tartalmaznak. Atalálmány tárgya fájdalőmcsillapító hatású vegyületek terápiáskőmbiná- ciója. ŕThe subject of the invention is pharmaceutical preparations suitable for the treatment of pain, which contain azacyclic, azabicyclic or tetrahydropyridine compounds of general formula (I) as the active ingredient. The subject of the invention is a therapeutic stone combination of pain-relieving compounds. ŕ

HU0000110A 1995-12-07 1996-12-05 Pharmaceutical compositions comprising azacyclic, azabicyclic or tetrahydro-pyridine-derivatives suitable for treating pain HUP0000110A3 (en)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US829895P 1995-12-07 1995-12-07
US831295P 1995-12-07 1995-12-07
US831395P 1995-12-07 1995-12-07
US829595P 1995-12-07 1995-12-07
US831895P 1995-12-07 1995-12-07
US830695P 1995-12-07 1995-12-07
US831995P 1995-12-07 1995-12-07
PCT/US1996/019390 WO1997020556A1 (en) 1995-12-07 1996-12-05 Method for treating pain

Publications (2)

Publication Number Publication Date
HUP0000110A2 true HUP0000110A2 (en) 2000-06-28
HUP0000110A3 HUP0000110A3 (en) 2000-09-28

Family

ID=27567403

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0000110A HUP0000110A3 (en) 1995-12-07 1996-12-05 Pharmaceutical compositions comprising azacyclic, azabicyclic or tetrahydro-pyridine-derivatives suitable for treating pain

Country Status (14)

Country Link
EP (1) EP0866702A4 (en)
JP (1) JP2000501711A (en)
KR (1) KR19990071977A (en)
CN (1) CN1208348A (en)
AU (1) AU715645B2 (en)
CA (1) CA2239732A1 (en)
CZ (1) CZ174598A3 (en)
EA (1) EA199800535A1 (en)
HU (1) HUP0000110A3 (en)
IL (1) IL124786A0 (en)
NO (1) NO982582L (en)
NZ (1) NZ324594A (en)
PL (1) PL327144A1 (en)
WO (1) WO1997020556A1 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1189902B1 (en) 1999-06-04 2003-08-27 Eli Lilly And Company 7-oxo-2-azabicyclo[2.2.1]heptanes as selective muscarinic receptor antagonist
US10195153B2 (en) 2013-08-12 2019-02-05 Pharmaceutical Manufacturing Research Services, Inc. Extruded immediate release abuse deterrent pill
WO2015095391A1 (en) 2013-12-17 2015-06-25 Pharmaceutical Manufacturing Research Services, Inc. Extruded extended release abuse deterrent pill
US9492444B2 (en) 2013-12-17 2016-11-15 Pharmaceutical Manufacturing Research Services, Inc. Extruded extended release abuse deterrent pill
CA2955229C (en) 2014-07-17 2020-03-10 Pharmaceutical Manufacturing Research Services, Inc. Immediate release abuse deterrent liquid fill dosage form
EP3209282A4 (en) 2014-10-20 2018-05-23 Pharmaceutical Manufacturing Research Services, Inc. Extended release abuse deterrent liquid fill dosage form
US20220144817A1 (en) * 2019-02-22 2022-05-12 Karuna Therapeutics, Inc. Compounds and methods of deuterated xanomeline for treating neurological disorders
WO2021097427A1 (en) 2019-11-15 2021-05-20 Karuna Therapeutics, Inc. Xanomeline derivatives and methods for treating neurological disorders
CN115974863A (en) * 2021-10-14 2023-04-18 南京迈诺威医药科技有限公司 Malate of xanomeline derivative, crystal form A, preparation method of malate, and application of crystal form A

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5043345A (en) * 1989-02-22 1991-08-27 Novo Nordisk A/S Piperidine compounds and their preparation and use
DK198590D0 (en) * 1990-08-21 1990-08-21 Novo Nordisk As HETEROCYCLIC COMPOUNDS, THEIR PREPARATION AND USE
US5376668A (en) * 1990-08-21 1994-12-27 Novo Nordisk A/S Heterocyclic compounds
US5527813A (en) * 1990-08-21 1996-06-18 Novo Nordisk A/S Heterocyclic compounds and their preparation and use
WO1993014089A1 (en) * 1992-01-13 1993-07-22 Novo Nordisk A/S Heterocyclic compounds and their preparation and use
US5605701A (en) * 1995-02-17 1997-02-25 Eli Lilly And Company Transdermal formulation

Also Published As

Publication number Publication date
CA2239732A1 (en) 1997-06-12
JP2000501711A (en) 2000-02-15
NO982582L (en) 1998-08-03
EP0866702A4 (en) 2001-07-25
AU1147697A (en) 1997-06-27
EP0866702A1 (en) 1998-09-30
KR19990071977A (en) 1999-09-27
NZ324594A (en) 1999-09-29
EA199800535A1 (en) 1998-12-24
IL124786A0 (en) 1999-01-26
HUP0000110A3 (en) 2000-09-28
WO1997020556A1 (en) 1997-06-12
NO982582D0 (en) 1998-06-05
PL327144A1 (en) 1998-11-23
CN1208348A (en) 1999-02-17
CZ174598A3 (en) 1999-01-13
AU715645B2 (en) 2000-02-10

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