HUE062236T2 - Vérlemezke funkció inhibitorok és eljárás azok alkalmazására - Google Patents

Vérlemezke funkció inhibitorok és eljárás azok alkalmazására

Info

Publication number
HUE062236T2
HUE062236T2 HUE19722359A HUE19722359A HUE062236T2 HU E062236 T2 HUE062236 T2 HU E062236T2 HU E19722359 A HUE19722359 A HU E19722359A HU E19722359 A HUE19722359 A HU E19722359A HU E062236 T2 HUE062236 T2 HU E062236T2
Authority
HU
Hungary
Prior art keywords
inhibitors
methods
same
platelet function
platelet
Prior art date
Application number
HUE19722359A
Other languages
English (en)
Inventor
Michael Holinstat
Reheman Adili
Andrew White
Theodore R Holman
Original Assignee
Univ Michigan Regents
Univ California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Michigan Regents, Univ California filed Critical Univ Michigan Regents
Publication of HUE062236T2 publication Critical patent/HUE062236T2/hu

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/081,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C07D249/101,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D249/12Oxygen or sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HUE19722359A 2018-04-17 2019-04-17 Vérlemezke funkció inhibitorok és eljárás azok alkalmazására HUE062236T2 (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201862659024P 2018-04-17 2018-04-17

Publications (1)

Publication Number Publication Date
HUE062236T2 true HUE062236T2 (hu) 2023-10-28

Family

ID=66429584

Family Applications (1)

Application Number Title Priority Date Filing Date
HUE19722359A HUE062236T2 (hu) 2018-04-17 2019-04-17 Vérlemezke funkció inhibitorok és eljárás azok alkalmazására

Country Status (9)

Country Link
US (2) US11498905B2 (hu)
EP (1) EP3781558B1 (hu)
CN (1) CN113015725A (hu)
CA (1) CA3134447A1 (hu)
DK (1) DK3781558T3 (hu)
ES (1) ES2942214T3 (hu)
HU (1) HUE062236T2 (hu)
PL (1) PL3781558T3 (hu)
WO (1) WO2019204447A1 (hu)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009143039A2 (en) * 2008-05-19 2009-11-26 Schering Corporation Heterocyclic compounds as factor ixa inhibitors
TW201319068A (zh) * 2011-08-05 2013-05-16 必治妥美雅史谷比公司 作為xia因子抑制劑之環狀p1接合劑
KR102086934B1 (ko) * 2015-07-29 2020-03-09 브리스톨-마이어스 스큅 컴퍼니 알킬 또는 시클로알킬 P2' 모이어티를 갖는 인자 XIa 마크로시클릭 억제제
US11111222B2 (en) * 2016-06-23 2021-09-07 The Regents Of The University Of Michigan Hydroxyeicosatrienoic acid compounds and their use as therapeutic agents

Also Published As

Publication number Publication date
EP3781558B1 (en) 2023-03-01
DK3781558T3 (da) 2023-04-03
PL3781558T3 (pl) 2023-05-02
US11498905B2 (en) 2022-11-15
ES2942214T3 (es) 2023-05-30
WO2019204447A1 (en) 2019-10-24
US20230140210A1 (en) 2023-05-04
CN113015725A (zh) 2021-06-22
CA3134447A1 (en) 2019-10-24
US20210363113A1 (en) 2021-11-25
EP3781558A1 (en) 2021-02-24

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