HUE054405T2 - Aciltiourea vegyület mezilsavsója, annak kristálya és elõállítási eljárás arra - Google Patents

Aciltiourea vegyület mezilsavsója, annak kristálya és elõállítási eljárás arra

Info

Publication number
HUE054405T2
HUE054405T2 HUE16786581A HUE16786581A HUE054405T2 HU E054405 T2 HUE054405 T2 HU E054405T2 HU E16786581 A HUE16786581 A HU E16786581A HU E16786581 A HUE16786581 A HU E16786581A HU E054405 T2 HUE054405 T2 HU E054405T2
Authority
HU
Hungary
Prior art keywords
crystal
acid salt
production processes
mesylic acid
processes therefor
Prior art date
Application number
HUE16786581A
Other languages
English (en)
Inventor
Ayako Sato
Original Assignee
Taiho Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Taiho Pharmaceutical Co Ltd filed Critical Taiho Pharmaceutical Co Ltd
Publication of HUE054405T2 publication Critical patent/HUE054405T2/hu

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/17Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13Crystalline forms, e.g. polymorphs

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Quinoline Compounds (AREA)
HUE16786581A 2015-04-30 2016-04-28 Aciltiourea vegyület mezilsavsója, annak kristálya és elõállítási eljárás arra HUE054405T2 (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2015092815 2015-04-30

Publications (1)

Publication Number Publication Date
HUE054405T2 true HUE054405T2 (hu) 2021-09-28

Family

ID=57199144

Family Applications (1)

Application Number Title Priority Date Filing Date
HUE16786581A HUE054405T2 (hu) 2015-04-30 2016-04-28 Aciltiourea vegyület mezilsavsója, annak kristálya és elõállítási eljárás arra

Country Status (11)

Country Link
US (1) US10143688B2 (hu)
EP (1) EP3290405B1 (hu)
JP (1) JP6676626B2 (hu)
CN (1) CN107614489B (hu)
DK (1) DK3290405T3 (hu)
ES (1) ES2863586T3 (hu)
HK (1) HK1247200A1 (hu)
HU (1) HUE054405T2 (hu)
PL (1) PL3290405T3 (hu)
PT (1) PT3290405T (hu)
WO (1) WO2016175305A1 (hu)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110312511B (zh) * 2017-02-15 2023-10-27 大鹏药品工业株式会社 医药组合物
KR102584306B1 (ko) 2017-09-08 2023-10-04 다이호야쿠힌고교 가부시키가이샤 항종양제 및 항종양 효과 증강제
AU2019342447A1 (en) 2018-09-18 2021-04-08 Taiho Pharmaceutical Co., Ltd. Combination therapy of acylthiourea compound and abiraterone
TW202140426A (zh) * 2020-02-14 2021-11-01 日商大鵬藥品工業股份有限公司 醯基硫脲化合物的製造方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2720552C (en) * 2008-04-10 2016-06-14 Taiho Pharmaceutical Co., Ltd. Acylthiourea compound or salt thereof, and use thereof
TWI594986B (zh) * 2011-12-28 2017-08-11 Taiho Pharmaceutical Co Ltd Antineoplastic agent effect enhancer
US9149471B2 (en) * 2013-09-30 2015-10-06 National University Corporation Tokyo University Of Agriculture And Technology Therapeutic agent for osteoporosis

Also Published As

Publication number Publication date
HK1247200A1 (zh) 2018-09-21
PT3290405T (pt) 2021-03-23
EP3290405B1 (en) 2021-02-17
JPWO2016175305A1 (ja) 2018-04-12
US20180161317A1 (en) 2018-06-14
ES2863586T3 (es) 2021-10-11
WO2016175305A1 (ja) 2016-11-03
US10143688B2 (en) 2018-12-04
PL3290405T3 (pl) 2021-07-12
JP6676626B2 (ja) 2020-04-08
CN107614489B (zh) 2021-05-11
DK3290405T3 (da) 2021-03-22
EP3290405A1 (en) 2018-03-07
EP3290405A4 (en) 2018-09-12
CN107614489A (zh) 2018-01-19

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