HUE051913T2 - Csökkentett kodon mutagenezis - Google Patents
Csökkentett kodon mutagenezisInfo
- Publication number
- HUE051913T2 HUE051913T2 HUE17190712A HUE17190712A HUE051913T2 HU E051913 T2 HUE051913 T2 HU E051913T2 HU E17190712 A HUE17190712 A HU E17190712A HU E17190712 A HUE17190712 A HU E17190712A HU E051913 T2 HUE051913 T2 HU E051913T2
- Authority
- HU
- Hungary
- Prior art keywords
- codon mutagenesis
- reduced codon
- reduced
- mutagenesis
- codon
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/102—Mutagenizing nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/102—Mutagenizing nucleic acids
- C12N15/1027—Mutagenizing nucleic acids by DNA shuffling, e.g. RSR, STEP, RPR
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/67—General methods for enhancing the expression
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B40/00—Libraries per se, e.g. arrays, mixtures
- C40B40/04—Libraries containing only organic compounds
- C40B40/06—Libraries containing nucleotides or polynucleotides, or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B50/00—Methods of creating libraries, e.g. combinatorial synthesis
- C40B50/06—Biochemical methods, e.g. using enzymes or whole viable microorganisms
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Crystallography & Structural Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12/562,988 US8383346B2 (en) | 2008-06-13 | 2009-09-18 | Combined automated parallel synthesis of polynucleotide variants |
| PCT/US2009/057507 WO2010144103A1 (en) | 2009-06-11 | 2009-09-18 | Combined automated parallel synthesis of polynucleotide variants |
| US28387709P | 2009-12-09 | 2009-12-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HUE051913T2 true HUE051913T2 (hu) | 2021-04-28 |
Family
ID=43759019
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HUE17190712A HUE051913T2 (hu) | 2009-09-18 | 2010-09-17 | Csökkentett kodon mutagenezis |
| HUE10817881A HUE037123T2 (hu) | 2009-09-18 | 2010-09-17 | Csökkentett kodon mutagenezis |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HUE10817881A HUE037123T2 (hu) | 2009-09-18 | 2010-09-17 | Csökkentett kodon mutagenezis |
Country Status (5)
| Country | Link |
|---|---|
| EP (2) | EP2478137B1 (hu) |
| DK (2) | DK3301208T3 (hu) |
| HU (2) | HUE051913T2 (hu) |
| SG (1) | SG179197A1 (hu) |
| WO (1) | WO2011035105A1 (hu) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL263448B2 (en) | 2016-06-09 | 2023-10-01 | Codexis Inc | Biological catalysts and methods for hydroxylation of chemical compounds |
| BR112018075932A2 (pt) | 2016-06-15 | 2019-10-01 | Codexis Inc | variante de beta-glicosidase de ocorrência não natural, polinucleotídeo recombinante, vetor, célula hospedeira, métodos para produção de pelo menos uma variante de beta-glicosidade de ocorrência não natural, para conversão de um substrato aceptor de grupo glicosila em um produto beta-glicosilado e para transglicosilação de um substrato, e, composição. |
| IL264686B2 (en) | 2016-08-26 | 2024-07-01 | Codexis Inc | Engineered imine reductases and methods for reversible amination of ketone and amine compounds |
| CN114901820B (zh) * | 2019-12-30 | 2024-01-19 | 南京金斯瑞生物科技有限公司 | 构建基因突变文库的方法 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6335160B1 (en) | 1995-02-17 | 2002-01-01 | Maxygen, Inc. | Methods and compositions for polypeptide engineering |
| US5605793A (en) | 1994-02-17 | 1997-02-25 | Affymax Technologies N.V. | Methods for in vitro recombination |
| US5837458A (en) | 1994-02-17 | 1998-11-17 | Maxygen, Inc. | Methods and compositions for cellular and metabolic engineering |
| FI104465B (fi) | 1995-06-14 | 2000-02-15 | Valio Oy | Proteiinihydrolysaatteja allergioiden hoitamiseksi tai estämiseksi, niiden valmistus ja käyttö |
| US6326204B1 (en) | 1997-01-17 | 2001-12-04 | Maxygen, Inc. | Evolution of whole cells and organisms by recursive sequence recombination |
| IL136574A0 (en) | 1997-12-08 | 2001-06-14 | California Inst Of Techn | A method for forming a polynucleotide of desired properties |
| JP4221100B2 (ja) | 1999-01-13 | 2009-02-12 | エルピーダメモリ株式会社 | 半導体装置 |
| EP1130093A1 (en) | 1999-01-19 | 2001-09-05 | Maxygen, Inc. | Oligonucleotide mediated nucleic acid recombination |
| WO2001075767A2 (en) | 2000-03-30 | 2001-10-11 | Maxygen, Inc. | In silico cross-over site selection |
| DE60144145D1 (de) | 2000-04-03 | 2011-04-14 | Maxygen Inc | Subtilisin-variante |
| BRPI0413501A (pt) | 2003-08-11 | 2006-10-10 | Codexis Inc | polipetìdeo, polinucleotìdeo isolado ou recombinante, vetor de expressão, célula hospedeira, e, método de preparar um polipetìdeo de hhdh |
| EP1654354A1 (en) | 2003-08-11 | 2006-05-10 | Codexis, Inc. | Improved ketoreductase polypeptides and related polynucleotides |
| BRPI0619225A2 (pt) * | 2005-12-01 | 2017-11-07 | Domantis Ltd | monômero de anticorpo de domínio, ligando, ácidos nucleicos isolado e recombinante, vetor, célula hospedeira, método para produzir um monômero de dab de ligando, composição farmacêutica, dispositivo de liberação de medicamento, uso de um monômero de anticorpo de domínio, e, método para tratar uma doença inflamatória, artrite ou doença respiratória |
| WO2008103474A1 (en) * | 2007-02-20 | 2008-08-28 | Anaptysbio, Inc. | Methods of generating libraries and uses thereof |
| WO2009088928A2 (en) * | 2007-12-31 | 2009-07-16 | Xoma Technology Ltd. | Libraries, arrays and their uses for targeted affinity enhancement |
| US8383346B2 (en) * | 2008-06-13 | 2013-02-26 | Codexis, Inc. | Combined automated parallel synthesis of polynucleotide variants |
-
2010
- 2010-09-17 WO PCT/US2010/049251 patent/WO2011035105A1/en active Application Filing
- 2010-09-17 DK DK17190712.4T patent/DK3301208T3/da active
- 2010-09-17 EP EP10817881.5A patent/EP2478137B1/en active Active
- 2010-09-17 EP EP17190712.4A patent/EP3301208B1/en active Active
- 2010-09-17 HU HUE17190712A patent/HUE051913T2/hu unknown
- 2010-09-17 SG SG2012018917A patent/SG179197A1/en unknown
- 2010-09-17 DK DK10817881.5T patent/DK2478137T3/da active
- 2010-09-17 HU HUE10817881A patent/HUE037123T2/hu unknown
Also Published As
| Publication number | Publication date |
|---|---|
| HUE037123T2 (hu) | 2018-08-28 |
| EP2478137A4 (en) | 2013-10-23 |
| WO2011035105A1 (en) | 2011-03-24 |
| EP3301208A1 (en) | 2018-04-04 |
| DK2478137T3 (da) | 2017-11-27 |
| EP2478137A1 (en) | 2012-07-25 |
| DK3301208T3 (da) | 2020-12-14 |
| EP2478137B1 (en) | 2017-09-13 |
| SG179197A1 (en) | 2012-04-27 |
| EP3301208B1 (en) | 2020-11-04 |
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