HUE049347T2 - Antigénspecifikus T-sejt-receptor génjét tartalmazó pluripotens õssejtek elõállítására szolgáló eljárás - Google Patents

Antigénspecifikus T-sejt-receptor génjét tartalmazó pluripotens õssejtek elõállítására szolgáló eljárás

Info

Publication number
HUE049347T2
HUE049347T2 HUE15822874A HUE15822874A HUE049347T2 HU E049347 T2 HUE049347 T2 HU E049347T2 HU E15822874 A HUE15822874 A HU E15822874A HU E15822874 A HUE15822874 A HU E15822874A HU E049347 T2 HUE049347 T2 HU E049347T2
Authority
HU
Hungary
Prior art keywords
antigen
specific
stem cells
production method
pluripotent stem
Prior art date
Application number
HUE15822874A
Other languages
English (en)
Inventor
Kyoko Masuda
Takuya Maeda
Yoshimoto Katsura
Original Assignee
Kawamoto Hiroshi
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=55078639&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HUE049347(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Kawamoto Hiroshi filed Critical Kawamoto Hiroshi
Publication of HUE049347T2 publication Critical patent/HUE049347T2/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/46—Cellular immunotherapy
    • A61K39/461—Cellular immunotherapy characterised by the cell type used
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/46—Cellular immunotherapy
    • A61K39/463—Cellular immunotherapy characterised by recombinant expression
    • A61K39/4632—T-cell receptors [TCR]; antibody T-cell receptor constructs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/46—Cellular immunotherapy
    • A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
    • A61K39/4643—Vertebrate antigens
    • A61K39/4644—Cancer antigens
    • A61K39/464452—Transcription factors, e.g. SOX or c-MYC
    • A61K39/464453—Wilms tumor 1 [WT1]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/7051—T-cell receptor (TcR)-CD3 complex
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0636—T lymphocytes
    • C12N5/0638—Cytotoxic T lymphocytes [CTL] or lymphokine activated killer cells [LAK]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0696—Artificially induced pluripotent stem cells, e.g. iPS
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A61K2039/572—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 cytotoxic response
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/45—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from artificially induced pluripotent stem cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cell Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Developmental Biology & Embryology (AREA)
  • Transplantation (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
HUE15822874A 2014-07-18 2015-07-17 Antigénspecifikus T-sejt-receptor génjét tartalmazó pluripotens õssejtek elõállítására szolgáló eljárás HUE049347T2 (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201462026336P 2014-07-18 2014-07-18

Publications (1)

Publication Number Publication Date
HUE049347T2 true HUE049347T2 (hu) 2020-09-28

Family

ID=55078639

Family Applications (1)

Application Number Title Priority Date Filing Date
HUE15822874A HUE049347T2 (hu) 2014-07-18 2015-07-17 Antigénspecifikus T-sejt-receptor génjét tartalmazó pluripotens õssejtek elõállítására szolgáló eljárás

Country Status (14)

Country Link
US (1) US20170304417A1 (hu)
EP (1) EP3170896B1 (hu)
JP (1) JP6942466B2 (hu)
CN (1) CN107002036A (hu)
AU (1) AU2015290560B2 (hu)
CY (1) CY1122993T1 (hu)
DK (1) DK3170896T3 (hu)
ES (1) ES2793025T3 (hu)
HU (1) HUE049347T2 (hu)
LT (1) LT3170896T (hu)
PL (1) PL3170896T3 (hu)
PT (1) PT3170896T (hu)
SI (1) SI3170896T1 (hu)
WO (1) WO2016010154A1 (hu)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106536718B (zh) 2014-05-21 2021-04-27 国立大学法人京都大学 胰芽细胞的制造方法及含有胰芽细胞的胰疾病治疗剂
US11834757B2 (en) * 2017-12-06 2023-12-05 New York Blood Center, Inc. HLA homozygous induced pluripotent stem cell (iPSC) libraries
US20210381008A1 (en) * 2018-07-26 2021-12-09 Kyoto University Method for producing foreign antigen receptor gene-introduced cell
EP4215604A1 (en) * 2020-09-18 2023-07-26 Thyas Co. Ltd. Method for producing regenerated t cells via ips cells
EP4219707A1 (en) 2020-09-24 2023-08-02 Kyoto University Method for producing effector cell having desired specificity

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006306822A (ja) * 2005-05-02 2006-11-09 Japan Science & Technology Agency 移植片拒絶反応及び移植片対宿主疾患を防ぐ移植免疫反応抑制ポリフェノール溶液及び移植免疫反応抑制方法
US20090217403A1 (en) * 2005-06-06 2009-08-27 Hergen Spits Means and methods for generating a t cell against an antigen of interest
WO2011068962A1 (en) * 2009-12-03 2011-06-09 The University Of Utah Research Foundation Methods for generating t lymphocytes from hematopoietic stem cells
US9206394B2 (en) * 2010-02-03 2015-12-08 The University Of Tokyo Method for reconstructing immune function using pluripotent stem cells

Also Published As

Publication number Publication date
US20170304417A1 (en) 2017-10-26
LT3170896T (lt) 2020-07-10
WO2016010154A1 (ja) 2016-01-21
EP3170896A1 (en) 2017-05-24
CN107002036A (zh) 2017-08-01
ES2793025T3 (es) 2020-11-12
DK3170896T3 (da) 2020-06-08
EP3170896A4 (en) 2018-03-21
JP6942466B2 (ja) 2021-09-29
AU2015290560B2 (en) 2021-02-18
PT3170896T (pt) 2020-06-16
CY1122993T1 (el) 2021-10-29
PL3170896T3 (pl) 2020-11-02
JPWO2016010154A1 (ja) 2017-04-27
SI3170896T1 (sl) 2020-08-31
AU2015290560A1 (en) 2017-03-09
EP3170896B1 (en) 2020-03-11

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