HUE044630T2 - P38 MAP kinázt gátló indanil karbamid vegyületek - Google Patents

P38 MAP kinázt gátló indanil karbamid vegyületek

Info

Publication number
HUE044630T2
HUE044630T2 HUE15766935A HUE044630T2 HU E044630 T2 HUE044630 T2 HU E044630T2 HU E15766935 A HUE15766935 A HU E15766935A HU E044630 T2 HUE044630 T2 HU E044630T2
Authority
HU
Hungary
Prior art keywords
map kinase
urea compounds
kinase inhibiting
indanyl
indanyl urea
Prior art date
Application number
Other languages
English (en)
Inventor
Milind Rode
Sanjay Srivastava
Davindar Tuli
Deepak Rai
Prashant Gj
Shailesh Deshpande
Rameshchandra Gupta
Vijay Chauthaiwale
Chaitanya Dutt
Original Assignee
Torrent Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Torrent Pharmaceuticals Ltd filed Critical Torrent Pharmaceuticals Ltd
Publication of HUE044630T2 publication Critical patent/HUE044630T2/hu

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D241/00Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/06Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members
    • C07D241/08Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pulmonology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
HUE15766935 2014-08-29 2015-08-27 P38 MAP kinázt gátló indanil karbamid vegyületek HUE044630T2 (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IN2772MU2014 2014-08-29

Publications (1)

Publication Number Publication Date
HUE044630T2 true HUE044630T2 (hu) 2019-11-28

Family

ID=55398832

Family Applications (1)

Application Number Title Priority Date Filing Date
HUE15766935 HUE044630T2 (hu) 2014-08-29 2015-08-27 P38 MAP kinázt gátló indanil karbamid vegyületek

Country Status (19)

Country Link
US (1) US9963463B2 (hu)
EP (1) EP3186232B1 (hu)
BR (1) BR112017003930A2 (hu)
CA (1) CA2958410A1 (hu)
CY (1) CY1121708T1 (hu)
DK (1) DK3186232T3 (hu)
ES (1) ES2731429T3 (hu)
HR (1) HRP20191031T1 (hu)
HU (1) HUE044630T2 (hu)
LT (1) LT3186232T (hu)
MY (1) MY190027A (hu)
PH (1) PH12017500323A1 (hu)
PL (1) PL3186232T3 (hu)
PT (1) PT3186232T (hu)
RS (1) RS58889B1 (hu)
SG (1) SG11201701174VA (hu)
SI (1) SI3186232T1 (hu)
TR (1) TR201908937T4 (hu)
WO (1) WO2016030852A1 (hu)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9963463B2 (en) * 2014-08-29 2018-05-08 Torrent Pharmaceuticals Limited Urea-substituted indanes as P38 map kinase inhibitors
WO2020113094A1 (en) 2018-11-30 2020-06-04 Nuvation Bio Inc. Pyrrole and pyrazole compounds and methods of use thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2760012B1 (fr) 1997-02-26 2000-08-18 Oreal Compositions pour la teinture des fibres keratiniques contenant des para-aminophenols, procede de teinture, nouveaux para-aminophenols et leur procede de prepraration
KR20010013977A (ko) 1997-06-19 2001-02-26 블레어 큐. 퍼거슨 중성 p1 특이성 기를 갖는 인자 xa의 억제제
US20080300281A1 (en) 1997-12-22 2008-12-04 Jacques Dumas Inhibition of p38 Kinase Activity Using Aryl and Heteroaryl Substituted Heterocyclic Ureas
UA73492C2 (en) 1999-01-19 2005-08-15 Aromatic heterocyclic compounds as antiinflammatory agents
ATE386030T1 (de) 2002-02-25 2008-03-15 Boehringer Ingelheim Pharma 1,4-disubstituierte benzokondensierte cycloalkyl- harnstoffverbindungen zur behandlung von zytokinvermittelten erkrankungen
CN101636397B (zh) 2007-04-13 2012-06-13 中国人民解放军军事医学科学院毒物药物研究所 脲类化合物、其制备方法及其医药用途
JP5787976B2 (ja) 2010-04-08 2015-09-30 レスピバート・リミテツド P38mapキナーゼ阻害剤としてのピラゾリルウレア
US9963463B2 (en) * 2014-08-29 2018-05-08 Torrent Pharmaceuticals Limited Urea-substituted indanes as P38 map kinase inhibitors

Also Published As

Publication number Publication date
LT3186232T (lt) 2019-07-10
MY190027A (en) 2022-03-22
PH12017500323B1 (en) 2017-07-10
RS58889B1 (sr) 2019-08-30
HRP20191031T1 (hr) 2019-08-23
PT3186232T (pt) 2019-06-24
BR112017003930A2 (pt) 2018-03-06
WO2016030852A1 (en) 2016-03-03
TR201908937T4 (tr) 2019-07-22
EP3186232B1 (en) 2019-03-27
PL3186232T3 (pl) 2019-10-31
US9963463B2 (en) 2018-05-08
ES2731429T3 (es) 2019-11-15
SI3186232T1 (sl) 2019-08-30
US20170247390A1 (en) 2017-08-31
CA2958410A1 (en) 2016-03-03
PH12017500323A1 (en) 2017-07-10
CY1121708T1 (el) 2020-07-31
SG11201701174VA (en) 2017-03-30
DK3186232T3 (da) 2019-07-01
EP3186232A1 (en) 2017-07-05

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