HU9200065D0 - New phenyl-imidazolidines, process for producing them and process for preparing pharmaceutical preparatives containing said compounds - Google Patents
New phenyl-imidazolidines, process for producing them and process for preparing pharmaceutical preparatives containing said compoundsInfo
- Publication number
- HU9200065D0 HU9200065D0 HU9200065A HU9200065A HU9200065D0 HU 9200065 D0 HU9200065 D0 HU 9200065D0 HU 9200065 A HU9200065 A HU 9200065A HU 9200065 A HU9200065 A HU 9200065A HU 9200065 D0 HU9200065 D0 HU 9200065D0
- Authority
- HU
- Hungary
- Prior art keywords
- denotes
- imidazolidines
- compounds
- producing
- halogen
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/84—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
- C07D233/60—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms with hydrocarbon radicals, substituted by oxygen or sulfur atoms, attached to ring nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/28—Antiandrogens
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/72—Two oxygen atoms, e.g. hydantoin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/86—Oxygen and sulfur atoms, e.g. thiohydantoin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/88—Nitrogen atoms, e.g. allantoin
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- Urology & Nephrology (AREA)
- Dermatology (AREA)
- Diabetes (AREA)
- Reproductive Health (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9100185A FR2671348B1 (fr) | 1991-01-09 | 1991-01-09 | Nouvelles phenylimidazolidines, leur procede de preparation, leur application comme medicaments et les compositions pharmaceutiques les renfermant. |
Publications (3)
Publication Number | Publication Date |
---|---|
HU9200065D0 true HU9200065D0 (en) | 1992-03-30 |
HUT60250A HUT60250A (en) | 1992-08-28 |
HU223310B1 HU223310B1 (hu) | 2004-05-28 |
Family
ID=9408539
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU9200065A HU223310B1 (hu) | 1991-01-09 | 1992-01-08 | Fenil-imidazolidinonok, ezek tion- és iminoszármazékai, továbbá hatóanyagként azokat tartalmazó gyógyászati készítmények és eljárás előállításukra |
Country Status (17)
Country | Link |
---|---|
EP (1) | EP0494819B1 (hu) |
JP (1) | JP3383320B2 (hu) |
KR (1) | KR100238385B1 (hu) |
CN (1) | CN1049214C (hu) |
AT (1) | ATE140218T1 (hu) |
AU (1) | AU648376B2 (hu) |
CA (1) | CA2059052C (hu) |
DE (1) | DE69212007T2 (hu) |
DK (1) | DK0494819T3 (hu) |
ES (1) | ES2089425T3 (hu) |
FR (1) | FR2671348B1 (hu) |
GR (1) | GR3020510T3 (hu) |
HU (1) | HU223310B1 (hu) |
IE (1) | IE76143B1 (hu) |
RU (1) | RU2076101C1 (hu) |
UA (1) | UA45299C2 (hu) |
ZA (1) | ZA9290B (hu) |
Families Citing this family (44)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2693461B1 (fr) * | 1992-07-08 | 1994-09-02 | Roussel Uclaf | Nouvelles phénylimidazolidines substituées, leur procédé de préparation, leur application comme médicaments et les compositions pharmaceutiques les renfermant. |
FR2706456B1 (fr) * | 1993-06-18 | 1996-06-28 | Rhone Poulenc Agrochimie | Dérivés optiquement actifs de 2-imidazoline-5-ones et 2-imidazoline-5-thiones fongicides. |
US6002016A (en) * | 1991-12-20 | 1999-12-14 | Rhone-Poulenc Agrochimie | Fungicidal 2-imidazolin-5-ones and 2-imidazoline-5-thiones |
FR2685328B1 (fr) * | 1991-12-20 | 1995-12-01 | Rhone Poulenc Agrochimie | Derives de 2-imidazoline-5-ones et 2-imidazoline-5-thiones fongicides. |
FR2694290B1 (fr) * | 1992-07-08 | 1994-09-02 | Roussel Uclaf | Nouvelles phénylimidazolidines éventuellement substituées, leur procédé de préparation, leur application comme médicaments et les compositions pharmaceutiques les renfermant. |
US6008370A (en) * | 1992-11-25 | 1999-12-28 | Rhone-Poulenc Agrochimie | Fungicidal-2-alkoxy/haloalkoxy-1-(mono- or disubstituted)amino-4,4-disubstituted-2-imidazolin-5-ones |
DE4335438A1 (de) * | 1993-10-18 | 1995-04-20 | Bayer Ag | 4-Cyanophenyliminoheterocyclen |
FR2715402B1 (fr) * | 1994-01-05 | 1996-10-04 | Roussel Uclaf | Nouvelles phénylimidazolines éventuellement substituées, leur procédé et des intermédiaires de préparation, leur application comme médicaments et les compositions pharmaceutiques les renfermant. |
TW521073B (en) * | 1994-01-05 | 2003-02-21 | Hoechst Marion Roussel Inc | New optionally substituted phenylimidazolidines, their preparation process, their use as anti-androgenic agent and the pharmaceutical compositions containing them |
FR2724169B1 (fr) * | 1994-09-06 | 1997-01-03 | Roussel Uclaf | Nouvelles phenylimidazolidines eventuellement substituees, leur procede et des intermediaires de preparation, leur application comme medicaments et les compositions pharmaceutiques les renfermant |
FR2716110B1 (fr) | 1994-02-16 | 1996-04-05 | Roussel Uclaf | Compositions cosmétiques ou pharmaceutiques comprenant des liposomes. |
US5656651A (en) * | 1995-06-16 | 1997-08-12 | Biophysica Inc. | Androgenic directed compositions |
FR2741342B1 (fr) * | 1995-11-22 | 1998-02-06 | Roussel Uclaf | Nouvelles phenylimidazolidines fluorees ou hydroxylees, procede, intermediaires de preparation, application comme medicaments, nouvelle utilisation et compositions pharmaceutiques |
CA2413417A1 (en) * | 2000-06-28 | 2002-01-03 | Bristol-Myers Squibb Company | Selective androgen receptor modulators and methods for their identification, design and use |
EP1854798A3 (en) | 2000-09-19 | 2007-11-28 | Bristol-Myers Squibb Company | Fused heterocyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function |
US20040087548A1 (en) | 2001-02-27 | 2004-05-06 | Salvati Mark E. | Fused cyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function |
DE10322108B4 (de) * | 2003-05-09 | 2008-12-11 | Bayer Schering Pharma Aktiengesellschaft | Antiandrogene Pyrrolidine mit tumorhemmender Wirksamkeit |
US7271188B2 (en) | 2003-06-12 | 2007-09-18 | Chugai Seikayu Kabushiki Kaisha | Imidazolidine derivatives |
AU2004305075A1 (en) | 2003-12-19 | 2005-07-07 | The Regents Of The University Of California | Methods and materials for assessing prostate cancer therapies |
NZ550102A (en) | 2004-02-24 | 2010-10-29 | Univ California | Methods and materials for assessing prostate cancer therapies and compounds (thiohydantoine derivatives) |
EP1621536A1 (en) | 2004-07-27 | 2006-02-01 | Aventis Pharma S.A. | Amino cyclic urea derivatives, preparation thereof and pharmaceutical use thereof as kinase inhibitors |
WO2006028226A1 (ja) * | 2004-09-09 | 2006-03-16 | Chugai Seiyaku Kabushiki Kaisha | 新規イミダゾリジン誘導体およびその用途 |
KR101332924B1 (ko) | 2005-05-13 | 2013-11-26 | 더 리전트 오브 더 유니버시티 오브 캘리포니아 | 디아릴히단토인 화합물 |
US7709517B2 (en) | 2005-05-13 | 2010-05-04 | The Regents Of The University Of California | Diarylhydantoin compounds |
PL1891038T3 (pl) * | 2005-05-13 | 2009-04-30 | Lilly Co Eli | Podstawione n-arylopirolidyny jako selektywne modulatory receptora androgenowego |
US7709516B2 (en) | 2005-06-17 | 2010-05-04 | Endorecherche, Inc. | Helix 12 directed non-steroidal antiandrogens |
FR2896504B1 (fr) * | 2006-01-23 | 2012-07-13 | Aventis Pharma Sa | Nouveaux derives d'uree cyclique, leur preparation et leur utilisation pharmaceutique comme inhibiteurs de kinases |
HUE027894T2 (hu) | 2006-03-27 | 2016-11-28 | Univ California | Androgén receptor modulátor a prosztatarák és az androgén receptorral összefüggõ betegségek kezelésében |
SG10201408699TA (en) | 2006-03-29 | 2015-02-27 | Univ California | Diarylthiohydantoin compounds |
US8168667B2 (en) | 2006-05-31 | 2012-05-01 | Galapagos Nv | Imidazolidine derivatives, uses therefor, preparation thereof and compositions comprising such |
TW200846338A (en) * | 2007-02-01 | 2008-12-01 | Chugai Pharmaceutical Co Ltd | Pyridyl imidazolidine derivative having sulfamoyl group, and pharmaceutical use thereof |
US9284345B2 (en) | 2007-04-12 | 2016-03-15 | Endorecherche, Inc. | 17alpha-substituted steroids as systemic antiandrogens and selective androgen receptor modulators |
EP2620432A3 (en) | 2007-10-26 | 2013-12-18 | The Regents Of the University of California | Diarylhydantoin compounds |
WO2009097995A1 (de) * | 2008-02-07 | 2009-08-13 | Sanofi-Aventis | Neue phenyl-substituierte imidazolidine, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung |
FR2944524B1 (fr) | 2009-04-17 | 2012-11-30 | Ipsen Pharma Sas | Derives d'imidazolidine-2,4-dione et leur utilisation comme medicament |
TW201111378A (en) | 2009-09-11 | 2011-04-01 | Bayer Schering Pharma Ag | Substituted (heteroarylmethyl) thiohydantoins |
EP3124481B1 (en) | 2010-02-16 | 2018-03-28 | Aragon Pharmaceuticals, Inc. | Androgen receptor modulators and uses thereof |
SG10201912719TA (en) | 2012-09-26 | 2020-02-27 | Aragon Pharmaceuticals Inc | Anti-androgens for the treatment of non-metastatic castrate-resistant prostate cancer |
JOP20200097A1 (ar) | 2013-01-15 | 2017-06-16 | Aragon Pharmaceuticals Inc | معدل مستقبل أندروجين واستخداماته |
US9682960B2 (en) | 2013-12-19 | 2017-06-20 | Endorecherche, Inc. | Non-steroidal antiandrogens and selective androgen receptor modulators with a pyridyl moiety |
CN103965112A (zh) * | 2014-05-13 | 2014-08-06 | 上海孚一生物科技有限公司 | 一种具有抗雄激素活性的化合物、制备方法及其应用 |
TWI726969B (zh) | 2016-01-11 | 2021-05-11 | 比利時商健生藥品公司 | 用作雄性激素受體拮抗劑之經取代之硫尿囊素衍生物 |
AU2018351714A1 (en) | 2017-10-16 | 2020-04-30 | Aragon Pharmaceuticals, Inc. | Anti-androgens for the treatment of non-metastatic castration-resistant prostate cancer |
CN113024513A (zh) * | 2021-03-22 | 2021-06-25 | 中国药科大学 | 新型雄激素受体降解剂、制备方法和医药用途 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3823240A (en) * | 1970-10-06 | 1974-07-09 | Rhone Poulenc Sa | Fungicidal hydantoin derivatives |
FR2329276A1 (fr) * | 1975-10-29 | 1977-05-27 | Roussel Uclaf | Nouvelles imidazolidines substituees, procede de preparation, application comme medicament et compositions les renfermant |
IL55774A (en) * | 1977-10-28 | 1982-04-30 | Sparamedica Ag | Pharmaceutical compositions containing urea derivatives,certain such novel derivatives and their manufacture |
MC1220A1 (fr) * | 1977-10-28 | 1979-07-20 | Hoffmann La Roche | Nouveaux derives d'imidazolidine |
DE2933917A1 (de) * | 1979-08-22 | 1981-03-26 | Basf Ag, 67063 Ludwigshafen | 5-imino-imidazolidin-2-one und diese enthaltende herbizide. |
DE3444918A1 (de) * | 1984-12-08 | 1986-06-12 | Hoechst Ag, 6230 Frankfurt | 1-phenyl-imidazol-5-carbonsaeure-derivate, ein verfahren zu ihrer herstellung und ihre verwendung als wachstumsregulatoren |
US4672101A (en) * | 1985-09-09 | 1987-06-09 | The Dow Chemical Company | Polyepoxy aromatic hydantoins |
FR2619381B1 (fr) * | 1987-08-13 | 1989-12-08 | Roussel Uclaf | Nouvelles imidazolidines substituees par un radical hydroxymethyle et un radical phenyl substitue, leur procede de preparation, leur application comme medicaments, les compositions pharmaceutiques les renfermant et un intermediaire pour leur preparation |
-
1991
- 1991-01-09 FR FR9100185A patent/FR2671348B1/fr not_active Expired - Fee Related
-
1992
- 1992-01-07 ZA ZA9290A patent/ZA9290B/xx unknown
- 1992-01-08 IE IE920059A patent/IE76143B1/en not_active IP Right Cessation
- 1992-01-08 KR KR1019920000124A patent/KR100238385B1/ko not_active IP Right Cessation
- 1992-01-08 DK DK92400038.3T patent/DK0494819T3/da active
- 1992-01-08 HU HU9200065A patent/HU223310B1/hu not_active IP Right Cessation
- 1992-01-08 AT AT92400038T patent/ATE140218T1/de not_active IP Right Cessation
- 1992-01-08 AU AU10106/92A patent/AU648376B2/en not_active Ceased
- 1992-01-08 RU SU925010932A patent/RU2076101C1/ru not_active IP Right Cessation
- 1992-01-08 CA CA002059052A patent/CA2059052C/fr not_active Expired - Fee Related
- 1992-01-08 ES ES92400038T patent/ES2089425T3/es not_active Expired - Lifetime
- 1992-01-08 DE DE69212007T patent/DE69212007T2/de not_active Expired - Fee Related
- 1992-01-08 EP EP92400038A patent/EP0494819B1/fr not_active Expired - Lifetime
- 1992-01-09 JP JP01935392A patent/JP3383320B2/ja not_active Expired - Fee Related
- 1992-01-09 CN CN92100140A patent/CN1049214C/zh not_active Expired - Fee Related
-
1993
- 1993-06-18 UA UA93003049A patent/UA45299C2/uk unknown
-
1996
- 1996-07-11 GR GR960400495T patent/GR3020510T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
RU2076101C1 (ru) | 1997-03-27 |
CN1063102A (zh) | 1992-07-29 |
CA2059052A1 (fr) | 1992-07-10 |
AU1010692A (en) | 1992-07-16 |
CN1049214C (zh) | 2000-02-09 |
EP0494819A1 (fr) | 1992-07-15 |
IE920059A1 (en) | 1992-07-15 |
DE69212007T2 (de) | 1997-01-09 |
AU648376B2 (en) | 1994-04-21 |
FR2671348A1 (fr) | 1992-07-10 |
UA45299C2 (uk) | 2002-04-15 |
DE69212007D1 (de) | 1996-08-14 |
HU223310B1 (hu) | 2004-05-28 |
ATE140218T1 (de) | 1996-07-15 |
HUT60250A (en) | 1992-08-28 |
ES2089425T3 (es) | 1996-10-01 |
KR100238385B1 (ko) | 2000-03-02 |
EP0494819B1 (fr) | 1996-07-10 |
JPH04308579A (ja) | 1992-10-30 |
ZA9290B (en) | 1993-03-31 |
GR3020510T3 (en) | 1996-10-31 |
JP3383320B2 (ja) | 2003-03-04 |
IE76143B1 (en) | 1997-10-08 |
KR920014786A (ko) | 1992-08-25 |
CA2059052C (fr) | 2004-11-23 |
FR2671348B1 (fr) | 1993-03-26 |
DK0494819T3 (da) | 1996-08-12 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
HU9200065D0 (en) | New phenyl-imidazolidines, process for producing them and process for preparing pharmaceutical preparatives containing said compounds | |
HUT64527A (en) | Method for producing phenyl-imidazolidine derivatives as well as medical preparatives containing said compounds | |
HU9303071D0 (en) | Process for producing of 5-lipoxygenase inhibiting 4-(4-phenyl-1-piperazinyl)-phenols and pharmaceutical compositions containing them | |
HUT47913A (en) | Process for production of substituated quinolinederivatives and medical compositions containing these substances | |
IL96407A0 (en) | Diazine derivatives | |
CS145091A3 (en) | Isoxazole-4-carboxamides and amides of hydroxyalkylidene cyanacetic acid, medicaments comprising said compounds and their application | |
IL114537A (en) | Sulfonamide derivatives of azolones their preparation and pharmaceutical compositions containing them | |
DE68914488D1 (de) | 2-(2-Hydroxy-3-phenoxypropylamino)ethylphenoxyacetamide, Verfahren und Zwischenprodukte zu deren Herstellung. | |
ATE127452T1 (de) | Poly-4-aminopyrrole-2-carboxamide derivate, verfahren zu ihrer herstellung und diese enthaltende arzneimittel. | |
ATE88468T1 (de) | Arylalkoxycumarine, verfahren zu ihrer herstellung und diese enthaltende therapeutische mittel. | |
EP0486386A3 (en) | Novel derivatives of n-benzoylproline, process for their preparation and drugs containing them | |
HU9601217D0 (en) | Antracyclinone derivatives and their use for treating amyloidosis | |
ZA912618B (en) | 3-aminochroman derivatives,process for preparing these and pharmaceutical compositions containing them | |
MX25922A (es) | Pirido (3,4-b) pirrolo (1,2-e)(1,4,5)oxadiazepinasy compuestos analogos relacionados un procedimiento para su preparacion y su uso como medicamentos | |
ATE53839T1 (de) | 2,3-dihydro-3-phenyl-benzofuran-2-onacetamidderivate, verfahren zu ihrer herstellung und diese enthaltende arzneimittel. | |
IT1261958B (it) | 2-(sostituite immino)-tiazolidine e procedimento per la loro preparazione e loro impiego quali antianginose e/o analgesiche |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
DGB9 | Succession in title of applicant |
Owner name: HOECHST MARION ROUSSEL, FR |
|
DGB9 | Succession in title of applicant |
Owner name: AVENTIS PHARMA S.A., FR |
|
HFG4 | Patent granted, date of granting |
Effective date: 20040405 |
|
MM4A | Lapse of definitive patent protection due to non-payment of fees |