HU197594B - Liquid soap or cleaning agent composition with disinfecting effect - Google Patents

Abstract

The present invention relates to a disinfectant liquid soap or detergent composition. In the composition of the invention, 22 to 45 parts by weight of anionic and / or non-ionic detergent, 40 to 65 parts by weight of water, 0 to 15 parts by weight of additive, preferably emollient, viscosity modifier, colorant and / or fragrance, and disinfectant to 1-5% by weight of the composition additive. Disinfectant is an antimicrobial component comprising from 30 to 60 parts by weight of 2,4,4'-trichloro-2'-hydroxy-diphenyl ether, from 60 to 30 parts by weight of the o-hydroxy biphenyl compound of formula (I) wherein X is hydrogen or an alkali metal. , preferably sodium, Y is hydrogen or halogen, preferably chlorine and 4 to 15 parts by weight of C12 to C18 alkylpyridinium halide and 20 to 80 parts by weight of disodium salt of ethylenediamine tetraacetic acid per 100 parts by weight of antimicrobial component. ox o !! H2c - (OCH2-CH2) n-O-R, HCl - OSO3A I (II) C - ONH4 II 0 r2 - 0 - (C h2 - ch2o) m - 3b (H1) -1-

Description

The present invention relates to a liquid soap or detergent composition having a disinfectant effect.

As is known, compositions containing various disinfectants are widely used both for cleaning and for more hygienic cleaning, such as washing food utensils. Recently, the use of liquid formulations has increased because they can be used more conveniently and economically with less loss than solid formulations. The detergent is predominantly composed of the potassium salt of natural fatty acids, but these compounds also contain, to a greater or lesser extent, other synthetic anionic or nonionic detergents. As a disinfectant, they contain an antibacterial agent of a very wide variety of compounds from a chemical point of view. .

No. I8U248. The composition according to the Hungarian patent contains potassium salts of natural fatty acids and potassium salts of variously substituted sulfonic acids as detergent, while the disinfectant is ethanol, formaldehyde or 2,4,4'-trichloro-2'-hydroxydiphenyl ether.

2,4,4'-trichloro-2-hydroxydiphenyl ether, generally o-hydroxypiphenyl ether compounds having various substituents, are most commonly used as detergent in detergent liquid compositions containing detergent anionic or nonionic surfactants. These compounds have the advantage of being active against a wide range of microorganisms and protecting the skin. Their disadvantage, however, is that their presence causes an adverse color change (browning) in the composition and damages the fragrances conventional in such compositions. More _,; their main disadvantage, however, is that they have only a bacteriostatic effect and have no germicidal effect.

To overcome the above disadvantage, in addition to the said compounds, approximately four times the weight of free fatty acids is added to the composition (German Patent Publication No. 1,767,321) or organic phosphoric acid esters or inorganic phosphoric acids or their salts are used (4,235,733). U.S. Patent 4,282,110). To protect the fragrance, note 4,490,280. U.S. Pat. No. 4,124,123, which relates to the preparation of a solid composition, comprises the step of dispersing these disinfectant compounds in a fatty acid-based detergent component and then adding it to the other components.

A satisfactory solution to enhance the antibacterial effect is not known. Although the aforesaid Nos. 4,235,733 and 4,282,110. reference in U.S. Patents to the use of germicidal additives, namely, halogenated carbanylide derivatives; the problem cannot be considered solved. Namely, it has been found that the germicidal compounds which meet the requirements of the liquid soap and detergent compositions are either unsatisfactory due to their too narrow spectrum of action or their efficacy is reduced by other components of the composition, in particular detergents. A combination of several germicidal compounds would be desirable to broaden the spectrum of action. However, such compounds, due in most cases to their different chemical nature, are incompatible with each other, degrading or at least inhibiting their action.

It is an object of the present invention to provide a soap and detergent composition containing anionic and / or nonionic detergent which has a broad antibacterial and intense germicidal effect.

In the course of our research to achieve this goal, it has been found that a disinfectant additive which, in addition to the general bacteriostatic effect 2,4,4'-trichloro-2'-hydroxydiphenyl ether, is a bactericidal agent, also meets the other requirements of the soap and detergent compositions. containing an o-hydroxybiphenyl compound and an alkylpyridinium halide. The former is primarily active against Gram-negative bacteria, while the latter is active against Gram-positive bacteria. However, it has also been found that the antibacterial compounds listed above are not able to exert their otherwise beneficial effects due to the inhibitory effect of the detergents and partly of each other when used together in the type of liquid soap or detergent compositions defined above. However, in further investigations, it has been surprisingly discovered that the original lethality of these antibacterial compounds can be completely restored by adding sufficient amounts of ethylenediaminetetraacetate: AV disodium salt. Thus, by combining compounds r in a defined proportion with disodium salt of EDTA, a broad spectrum of disinfectant with intense germicidal activity can be used in liquid soap and detergent compositions containing anionic and / or nonionic detergents.

Based on this finding, the invention is such that

22 to 45 parts by weight of anionic and / or non-ionic detergent, 40 to 65 parts by weight of water, 0 to 15 parts by weight of additive, preferably emollient, viscosity modifier, colorant and / or fragrance, and 1 to 5% disinfectant based on the total weight of the components liquid soap or detergent composition containing 3C-60 'parts by weight of 2,4,4'-trichloro-2'-hydroxyddiylphenyl ether, 60-30 parts by weight of o-hydroxy compounds of formula I as antimicrobial component a biphenyl compound wherein X is hydrogen or an alkali metal, preferably sodium, Y is hydrogen or halogen, preferably chlorine, and

-2197594

It contains from 4 to 15 parts by weight of C 12 -C 18 alkylpyridinium halide and from 20 to 80 parts by weight of ethylenediaminetetraacetic acid disodium salt per 100 parts by weight of antimicrobial component.

As mentioned above, the composition of the invention contains from 22 to 45 parts by weight of anionic and / or nonionic detergent. Preferred anionic detergents are alkali salts of a synthetic surfactant such as C 6 -C 12 alkyl chains, dialkylsulfosuccinate alkali salts, mono- or diethanolamides of natural fatty acids, ammonium or alkali salts of fatty alcohol sulfates or non-ionic salts of dodecylbenzosulfonic acids as detergent, preferably alkylphenol polyglycol ethers containing from 8 to 14 carbon atoms and from 4 to 15 ethoxy units, alkyl polyglycol ethers from 12 to 18 carbon atoms and from 4 to 15 ethoxy units, or mixtures thereof according to the invention composition, but may also contain other compounds, such as alkyl polyglycol ether sulfate alkali salts or sodium tripolyphosphate. In addition to the above, any known anionic or nonionic detergent may be used in the composition of the invention.

Of course, the detergents for the soap compositions of the present invention must meet stricter requirements. They must not damage the skin and must generally comply with health regulations. Examining the detergents from this point of view, it was found that the alkali-ammonium mixed salts of the alkyl and alkenyl (polyethoxy) sulphosuccinate of formula (II) wherein R 1 is a C 12 -C 18 alkyl or alkenyl group with the proviso that the proportion of the alkenyl compound may be up to 3% by weight of the compounds of formula II, n is 4 to 8 and A is an alkali metal ion, having a prominent skin-like effect, e.g. non-ethoxylated) alkyl esters or their corresponding diesters or semi-ester dialkic salts. Further, it has been found that the combination of the compounds of formula II with a certain proportion of fatty alcohol sulfate salts and fatty acid ethanolamides results in a detergent which is substantially superior to conventional detergents both in terms of cleaning performance and health protection requirements.

According to this discovery, the liquid soap composition of the present invention having the same composition and other components, including the disinfectant additive, as defined above, is present in detergent in an amount of 40-80 parts by weight of at least one alkyl or alkenyl (polyethoxy) sulfosiccinate a mixed alkali-ammonium salt wherein R 1 is a C 12 -C 18 alkyl or alkenyl group, with the proviso that the proportion of the alkenyl compound may be up to 3% by weight of the compounds of formula II, n is 4 to 8 and A represent an alkali metal moiety, 2 to 10 parts by weight of an optionally ethoxylated fatty alcohol sulfate salt of formula III, wherein R ₂ is C 12 -C 14 alkyl, m is 0 to 6, and B is an alkali metal or ammonium salt. -ion, 4 to 14 parts by weight of mono- and / or diethanolamide of coconut and / or porcine fatty acids and, if desired, 3 containing up to 50 parts by weight of a multifunctional carboxylic acid and / or hydroxy carboxylic acid, preferably citric acid, lactic acid and / or tartaric acid.

The compounds of formula (II) are conveniently prepared from maleic anhydride. The starting compound is first semi-esterified with the appropriate ethoxylated fatty alcohol or a mixture thereof and then bis-fused to the semi-ester. The free carboxyl group of the resulting semi-ester of the alkali sulphosuccinate is then neutralized with ammonium hydroxide.

The disinfectant soap composition of the present invention preferably comprises, as an anionic detergent, a mixture of several compounds of formula II within the given quantitative range. These may be in any proportion with the proviso that the proportion of compounds of formula (II) containing an unsaturated esterification group may not exceed 3% by weight of the total amount of this compound.

As the fatty alcohol sulfate salt of formula (III), the liquid soap composition of the present invention may contain simple or ethoxylated alkali or ammonium salts of fatty alcohols having up to 6-ethoxy groups. Preferably the composition comprises sodium or ammonium salts of lauryl or myristyl sulfate. Ammonium salts were found to be most preferred.

The third component of the detergent combination, as mentioned above, is a mixture of mono- and / or diethanolamine of coconut fatty acid and / or pig fatty acid, preferably the corresponding diethanolamide or a mixture of diethanolamide compounds.

The multifunctional carboxylic acid or hydroxycarboxylic acid optionally present is intended primarily to control the pH of the liquid soap composition of the present invention. The pH of the composition is preferably 6.3 to 6.6, which may be adjusted using the above mentioned amounts of these acids.

The disinfectant additive of the present invention is particularly significant for compositions containing the detergents described above. These detergents would render the antimicrobial component of the disinfectant additive practically worthless if the additive did not contain the EDTA disodium salt.

In the disinfectant additive of the compositions of the invention, the X substituents of the compounds of formula I may be hydrogen or an alkali metal, preferably sodium 3.

-3197594 atoms, while the Y substituent may be hydrogen or halogen, preferably chlorine. Of these compounds, o-hydroxybiphenyl was found to be most preferred.

As alkylpyridinium halide, the disinfectant preferably contains N-hexadecylpyridinium bromide.

The disinfectant liquid soap or detergent compositions of the present invention may contain, in addition to those listed, additives customary in such compositions according to the needs of the user. Thus, it may contain glycerol, lanolin, polyethylene glycol as a viscosity modifier and a skin emollient, as well as ethyl alcohol, urea, fragrances and colorants, and other known additives. The amount of these additional additives is from 0 to 15 parts by weight, preferably from 3 to 10 parts by weight.

The disinfectant liquid soap or detergent composition of the present invention may be prepared by simply mixing the components. Advantageously, the detergents and the viscosity-altering components are first mixed together under gentle heating, and then acid is added to the resulting mixture to adjust to the desired pH value, followed by other additives, and finally the disinfectant additive. After mixing the components, a ready-to-use liquid composition is obtained.

The compositions of the present invention have the advantage of having a strong cleaning effect and a broad spectrum, intense antibacterial, germicidal effect in many applications. Industrial formulations can be successfully used, for example, in canning glass detergents, in the food industry, particularly in the meat industry, for washing various utensils and containers or for cleaning plastic containers. The soap composition is preferably used primarily as a disinfectant hand wash.

To demonstrate the disinfectant effect of the compositions of the present invention, bacteriological assays were performed according to a method known in the art (Breck, EG et al., Empfehlungen für die Prüfung und Bewertung, Wirksamkeit Chemischer Desiníektionsverfahren, Z. 380, 1977) and in the corresponding MSC No. 03-67 / 1, no. As required by the Health Sector Standard. 18-hour bouillon cultures of the following bacterial strains were used for the assays:

Staphylococcus aureus, Escherichia coli, Salmonella typhi, Proteus vulgaris and Pseudomonas aeruginosa. In addition to bacterological tests, the liquid soap formulations were also subjected to a practical handwashing test.

In general, it has been found that the compositions of the present invention exhibit a potent and broad spec 4 drum germicidal effect at even greater dilution. The results of the assay are described in detail in the Examples.

The invention is illustrated by the following examples.

Example 1

283 kg of an aqueous solution of 810 kg of a sodium sulfosuccinate ammonium salt of a fatty alcohol ethoxylate containing 12 to 18 carbon atoms (average carbon 16.5) and a 4-ethoxy group are charged into a stirred enamel container fitted with a heating jacket. The temperature of the 35% w / w solution is maintained at 30-35 ° C with gentle heating and a solution of 21 kg of lauryl sulfate ammonium salt in a similar concentration (60 kg) is added with stirring. While stirring at constant temperature, 50 kg of 100% coconut fatty acid diethanolamide, 50 kg of cosmetic grade glycerol and 15 kg of ethyl alcohol are added and the pH is adjusted to 6.4-6.5 with citric acid. in. This requires about 10-12 kg of citric acid.

The resulting yellow, translucent, honey-like viscosity mixture, weighing about 1000 kg, was blended with 8.8 kg of aroma and 2.5 kg of verdebrill.

Meanwhile, 5 kg of 2,4,4'-trichloro-2'-hydroxydiphenyl ether is dissolved in 10 kg of propylene glycol, and 5 kg of 2-hydroxybiphenyl in 40 ml of ethyl alcohol and 1 kg of N A solution of 40% ethyl alcohol in hexa deci 1-pyridinium bromide was prepared. Dissolve 3 kg of ethylenediaminetetraacetic acid disodium salt in 5 kg of water at 35 ° C.

The aforementioned solutions are mixed into the composition. We get a green, translucent, fragrant liquid soap that has a good foaming, intense soil removal and disinfecting effect, and is gentle on the skin.

To test the bacteriostatic and bactericidal activity of the resulting composition, serial dilutions of the 50% solution of the composition were made at a ratio of 1: 2 to 1: 1024, and the effect on various bacterial strains was compared by comparing the antibacterial activity of each composition. but without the EDTA disodium salt. Practical handwashing tests were also performed on both compositions.

A solution of 1.562% of the composition of Example 1 resulted in complete destruction of Staphylococcus auerus and Salmonella typhi, whereas it was completely destroyed by a solution of highly resistant Escherichia coli at 3.125%. Practical hand washing tests have yielded similar results. Assuming a hand wash time of 30 sec, 3-4 g of the preparation, when diluted with 10 times water at 40-50 ° C, completely eradicated all bacteria on the skin, including the highly resistant strain of Escherichia coli.

In contrast, the comparative composition without EDTA disodium salt showed significantly less antibacterial activity. It was found that even at a 1: 2 dilution, Gram-positive Staphylococcus aureus and Gram-negative Salmonella typhi did not die, and had a particularly unfavorable effect on Gram-negative Escherichia coli. In a hand washing experiment, a solution of 3 to 4 g of the preparation in 10 volumes of water at 40 to 50 ° C was used, assuming a hand wash time of 30 seconds. The results of the examination of the skin surface of the hand were similarly poor.

Example 2

810 kg of a 35% (w / w) aqueous solution of 35% potassium sulphosuccinate ammonium salt of fatty alcohol ethoxylate having 12 to 18 carbon atoms (average number of carbon atoms 16.0) containing 8% degree of ethoxylation. At C, it is mixed with the amounts of the components mentioned in Example 1, except that coconut fatty acid monoethanolamide is substituted for coconut fatty acid diethanolamide, and lanolin is substituted for glycerol and lactic acid is substituted for citric acid. The product of Example 1 gives a slightly higher viscosity and other properties the same liquid soap.

In biological assays similar to those described in Example 1, this composition also exhibited excellent antibacterial activity. Its 3.125% solution also completely destroyed the most resistant Escherichia coli bacteria.

Example 3

The procedure of Example 1 was followed except that the same amount of lauryl sulfate sodium salt, coconut fatty acid diethanolamide instead of lauryl sulfate ammonium salt and 200 molar polyethylene of glycerol were the same. glycol is added to the other components. The pH of the mixture is adjusted with tartaric acid this time. A liquid soap similar to that of Example 1 is obtained.

Example 4

3510% aqueous solution of 810 kg of sodium sulfosuccinate ammonium salt of C12-C18 saturated alkyl groups (average number of carbon atoms 15.7) is mixed with 35 kg of myristylsulfate ammonium salt (8 kg) in the same manner as in Example 1. water, 50 kg of coconut fatty acid diethanolamide and 15 kg of ethyl alcohol and finally the pH of the mixture is adjusted to 6.4 with citric acid.

In the same manner as in Example 1, solutions were prepared from 5 kg of 2,4,4'-trichloro-2'-hydroxydiphenyl ether, 3 kg of 2-hydroxybiphenyl sodium, 1 kg of N-hexadecylpyridinium bromide and 6 kg. EDTA disodium salt. These solutions are added to the composition and the mixture is homogenized. A yellow liquid soap having a viscosity of honey is obtained.

Example 5

234 kg of a 35% by weight solution of a potassium sulphosuccinate ammonium salt of fatty alcohol ethoxylate having 6 ethoxylation and 1.7% by weight unsaturated compounds containing 12 to 18 carbon atoms (average number of carbon atoms 15.2) was added to 1 kg. In a manner similar to that described in Example 1b, a solution of 63 kg of lauryl sulfate ammonium sc was added to a 35% by weight solution of 180 kg, followed by the addition of 60 kg of pig fatty acid monoethanolamide, 30 kg of lanolin and 40 kg of ethanol. The pH of the mixture was adjusted to 6.5 with tartaric acid. This requires about 10 kg of tartaric acid. To the resulting viscous mixture were added 8 kg of scent aroma and 2 kg of methylene blue dye and the disinfectant of Example 4 and mixed thoroughly. A blue-colored, well-foaming liquid soap is obtained.

Example 6

Here again, as in Example 1, 35% by weight of a total of 810 kg of water in the sodium sulfosuccinate ammonium salt of 283 kg of C12-C18 alkyl groups (average carbon number 15.6) is mixed with 22.7 kg of myristisulfaphammonium salt in a 35 wt.% solution of 65 kg. 70 kg of coconut fat acid diethanolamide, 12 kg of glycerol and 12 kg of ethanol are added and the pH is adjusted to 6.4 using about 15 kg of citric acid. Then 13 kg of scent aroma and 3 kg of verdebrill dye, the disinfectant of Example 4, are added and mixed thoroughly. High viscosity, green-colored translucent liquid soap with good foaming, good soil removal and skin protection.

\ 3-6. The formulations of Examples 1 to 8 are as described in

When subjected to the tests described in Example 1, it was found that they also exhibit excellent antibacterial activity. Even at high dilutions, the bacterial strains tested were destroyed and their 3.125% solution proved to be effective against the most resistant strain of Escherichia coli.

Example 7

An industrial cleanser was prepared by mixing the compound of Example 1 with 150 kg of nonylphenol polyglycol ether in aqueous solution, 80 kg of C12-C18 fatty alcohol sulphate sodium salt having an average carbon content of 15.2, 70 kg of C12-C18 sulfate. 5 over 5

-5197594 g-alkyl and 10-ethoxy alkyl polyglycol ether and 20 kg of sodium tripolyphosphate and make up to 1000 kg with water. To the aqueous solution were added 4 kg of 2,4,4'-trichloro-2'-hydroxydiphenyl ether, 4 kg of 2-hydroxybiphenyl, 1.5 kg of N-hexadecylpyridinium bromide and 5.5 kg of EDTA-. disodium salt solutions prepared as in Example 1.

The 7% aqueous solution of the liquid surfactant composition thus obtained is well suited for cleaning plastic food transport conveyors by soaking for 10 minutes and then rinsing with water. After the washing and subsequent rinsing operation, the treated surfaces were subjected to microbiological examination. Microbiological tests showed complete germination of the surfaces.

Example 8

In an apparatus according to Example 1, a solution of dodecylbenzenesulfonic acid and 40% NaOH in 800 kg of an aqueous solution of 10% dodecylbenzenesulfonic acid sodium salt was prepared. To this is added 100 kg of nonylphenol polyglycol ether, 40 kg of C12-C18 alkyl moiety of 4,6-ethoxylation grade alkyl polyglycol ether, 40 kg of sodium tripolyphosphate and 20 kg of citric acid.

The l. In the same manner as in Example 1, solutions were prepared from 5 kg of 2,4,4'-trichloro-2'-hydroxypiphenyl ether, 3 kg of 2-hydroxy-4-chlorobiphenyl, 1 kg of N-hexadecylpyridinium bromide and 6 kg of EDTA. -dinátriumsóból. The solutions are added to the above composition and the mixture is homogenized.

The composition thus obtained is particularly suitable for washing glassware and bottles in the canning industry. The disinfectant was tested by diluting it with 5% water and cleaning it at 60 ° C for 10 minutes by soaking in canned beer and beer bottles. The dishes were then flushed with 20 ° C water and the treated surfaces were subjected to bacteriological examination. A bactericidal effect was found to meet the requirements of the food industry.

Example 9

In the same manner as in Example 8, 1000 kg of a surfactant composition was prepared which contained 8% by weight of sodium salt of dodecylbenzenesulfonic acid, 7% by weight of nonylphenol polyglycol ether, 10% by weight of C12-C18, C16.1 alkyl. containing 5% by weight of sodium tripolyphosphate and 3% by weight of ethyl alcohol. To this are added 3.5 kg of 2,4,4'-trichloro-2'-hydroxypiphenyl ether, 5.5 kg of 2-hydroxybiphenyl sodium, 0.5 kg of N-hexadecylpyridinium bromide and 2 5 kg EDTA disodium salt l. The mixture was homogenized.

The resulting liquid detergent is well suited for cleaning heavily soiled, greasy, greasy slaughterhouse walls, tiles, walkways. The disinfectant was tested with a 3% solution in water and showed excellent antibacterial activity.

Example 10

The procedure of Example 1 was followed except that for the aqueous solution of the fatty alcohol ethoxylate sodium sulphosuccinate ammonium salt, instead of a 21 kg aqueous solution of the lauryl sulphate ammonium salt, C12-C14 fatty alcohol ethoxylate sulphate containing 6 ethoxy groups 60 kg of an aqueous solution of 35% by weight are added with stirring. Further operations were performed as described in Example 1 to give a translucent liquid appan having properties similar to those of Example 1.

Example 11

In the same manner as in Example 1, this time, for the aqueous solution of the fatty alcohol ethoxylate sodium sulfosuccinate ammonium salt, instead of 21 kg of the lauryl sulfate ammonium salt, 2 60 kg are added with stirring. Proceeding as in Example 1, the operations give a clear liquid soap having properties similar to those of Example 1.

Claims (4)

PATENT CLAIMS A disinfectant liquid soap or detergent composition comprising 22 to 45 parts by weight of anionic and / or nonionic detergent, 40 to 65 parts by weight of water, 0 to 15 parts by weight of an additive, preferably emollient, viscosity modifier, colorant and / or fragrance, and the composition. 1-5% by weight of the disinfectant, characterized in that the antimicrobial component contains 30-60 parts by weight of 2,4,4'-trichloro-2'-hydroxydiphenyl ether, 60-30 parts by weight of the compound of the formula I as antimicrobial component. a hydroxybiphenyl compound wherein X is hydrogen or an alkali metal, preferably sodium, Y is hydrogen or halogen, preferably chlorine, and 4 to 15 parts by weight of C12 -C18 alkylpyridinium halide and 20 to 80 parts by weight based on 100 parts by weight of antimicrobial component Contains disodium salt of ethylenediaminetetraacetic acid. (Priority: March 31, 1987) 2. Disinfectant liquid soap composition comprising 22 to 45 parts by weight of anionic detergent, 40 to 65 parts by weight of water, 015 parts by weight of an additive, preferably emollient, viscosity modifier, colorant and / or fragrance, and 1 to 5% by weight of the composition. characterized in that the anionic de-6197594 tergene is present in an amount of 40 to 80 parts by weight of at least one alkali-ammonium mixed salt of alkyl or alkenyl (polyethoxy) sulfosuccinate of formula II, wherein R 1 is C 12 -C 18 alkyl or alkenyl, with the proviso that the proportion of alkenyl compound may be up to 3% by weight of the compounds of formula II, n is 4-8 and A is an alkali metal, 2 to 10 parts by weight of an optionally ethoxylated fatty alcohol sulfate salt of formula III wherein R ₂ is C 12-14 alkyl and m is 0-6, B is an alkali metal. or an ammonium ion, an antiseptic additive of 4 to 14 parts by weight of mono- and / or diethanolamide of coconut fatty acids and / or diethylamide and optionally up to 3 parts by weight of multifunctional carboxylic and / or hydroxycarboxylic acids, and as an antimicrobial component, 30-60 parts by weight of 2,4,4'-trichloro-2'-hydroxydiphenyl ether, 60-30 parts by weight of the o-hydroxybiphenyl compound of formula I, wherein X is hydrogen or an alkali metal. , preferably sodium, Y is' hydrogen or halogen, preferably chlorine and 4 to 15 parts by weight of 12 to 18 carbon atoms of alkylpyridinium halide and 100 parts by weight of antimicrobial compound. It contains, by weight, between 20 and 80 parts by weight of a disodium salt of ethylenediaminetetraacetic acid. (Priority: 15.10.1987) 3. A.2. The composition of claim 1, wherein the fatty alcohol sulfate salt of formula (III) comprises a compound wherein m is 0, and R ₂ and B are as defined in claim 2. 15 Wed. (Priority: March 31, 1987) 4. A composition according to any one of claims 1 to 3, characterized in that it contains o-hydroxybifeml as a compound of formula (I). (Priority: March 31, 1987) 20 5. Figures 1-4. A composition according to any one of claims 1 to 3, characterized in that the alkylpyridinium halide contains N-hexadecylpyridinium bromido. (Priority: March 31, 1987)