HU177875B - Process for preparing ethylene-diol-acetals with cytostatic,hypotensive and analgetic activity - Google Patents

Process for preparing ethylene-diol-acetals with cytostatic,hypotensive and analgetic activity

Info

Publication number
HU177875B
HU177875B HU79NA1138A HUNA001138A HU177875B HU 177875 B HU177875 B HU 177875B HU 79NA1138 A HU79NA1138 A HU 79NA1138A HU NA001138 A HUNA001138 A HU NA001138A HU 177875 B HU177875 B HU 177875B
Authority
HU
Hungary
Prior art keywords
hypotensive
cytostatic
acetals
diol
preparing ethylene
Prior art date
Application number
HU79NA1138A
Other languages
Hungarian (hu)
Inventor
Albert Szent-Gyoergyi
Gabor B Fodor
Original Assignee
Cancer Res Nat Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cancer Res Nat Found filed Critical Cancer Res Nat Found
Publication of HU177875B publication Critical patent/HU177875B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D493/00Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/12Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/18Radicals substituted by singly bound oxygen or sulfur atoms
    • C07D317/20Free hydroxyl or mercaptan
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/26Radicals substituted by doubly bound oxygen or sulfur atoms or by two such atoms singly bound to the same carbon atom

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
HU79NA1138A 1978-06-20 1979-06-19 Process for preparing ethylene-diol-acetals with cytostatic,hypotensive and analgetic activity HU177875B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US91732778A 1978-06-20 1978-06-20

Publications (1)

Publication Number Publication Date
HU177875B true HU177875B (en) 1982-01-28

Family

ID=25438634

Family Applications (1)

Application Number Title Priority Date Filing Date
HU79NA1138A HU177875B (en) 1978-06-20 1979-06-19 Process for preparing ethylene-diol-acetals with cytostatic,hypotensive and analgetic activity

Country Status (14)

Country Link
JP (1) JPS5513274A (en)
AU (1) AU521500B2 (en)
CA (1) CA1142948A (en)
CH (1) CH641454A5 (en)
DE (1) DE2924077A1 (en)
DK (1) DK160828C (en)
FR (1) FR2429214A1 (en)
GB (1) GB2028309B (en)
HU (1) HU177875B (en)
IE (1) IE48434B1 (en)
IT (1) IT1121294B (en)
NL (1) NL7904249A (en)
NO (1) NO154966C (en)
SE (1) SE445643B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4238500A (en) * 1979-04-06 1980-12-09 National Foundation For Cancer Research Cyclic double hemiacetals of enediol compounds and compositions and methods for preparing and using same
EP0057699A4 (en) * 1980-08-14 1982-11-08 Nat Foundation For Cancer Res 5,6-o-isoalkylidene ascorbic acid derivatives.
TWI386448B (en) 2007-01-26 2013-02-21 Rohm & Haas Light-scattering compositions

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2108649C3 (en) * 1971-02-24 1978-12-07 Basf Ag, 6700 Ludwigshafen 2-methyl-2-hepten-6-on-l-al and its acetals
DE2232498A1 (en) * 1972-07-01 1974-01-10 Basf Ag METHOD FOR MANUFACTURING BENZILE MONOCETALS
DE2514001A1 (en) * 1975-03-29 1976-10-07 Basf Ag Glyoxal monoacetal prepn. from crotonaldehyde acetals - by ozonolysis in an organic solvent and reductive dissociation of the prod

Also Published As

Publication number Publication date
NO792040L (en) 1979-12-21
DK160828B (en) 1991-04-22
IE48434B1 (en) 1985-01-23
DK256679A (en) 1979-12-21
GB2028309B (en) 1982-08-04
JPS5513274A (en) 1980-01-30
DK160828C (en) 1991-10-14
DE2924077C2 (en) 1990-08-16
NO154966B (en) 1986-10-13
GB2028309A (en) 1980-03-05
SE445643B (en) 1986-07-07
NL7904249A (en) 1979-12-27
JPS6410515B2 (en) 1989-02-22
DE2924077A1 (en) 1980-01-17
SE7905330L (en) 1979-12-21
IT7923721A0 (en) 1979-06-20
FR2429214B1 (en) 1985-03-08
IT1121294B (en) 1986-04-02
AU521500B2 (en) 1982-04-08
AU4768979A (en) 1980-01-03
CH641454A5 (en) 1984-02-29
FR2429214A1 (en) 1980-01-18
CA1142948A (en) 1983-03-15
NO154966C (en) 1987-01-21

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Legal Events

Date Code Title Description
HU90 Patent valid on 900628
HMM4 Cancellation of final prot. due to non-payment of fee