HRP950485A2 - Combination of an opioid antagonist and a selective serotonin reuptake inhibitor for treatment of alcoholism and alcohol dependence - Google Patents

Combination of an opioid antagonist and a selective serotonin reuptake inhibitor for treatment of alcoholism and alcohol dependence Download PDF

Info

Publication number
HRP950485A2
HRP950485A2 HR08/308,859A HRP950485A HRP950485A2 HR P950485 A2 HRP950485 A2 HR P950485A2 HR P950485 A HRP950485 A HR P950485A HR P950485 A2 HRP950485 A2 HR P950485A2
Authority
HR
Croatia
Prior art keywords
serotonin reuptake
selective serotonin
reuptake inhibitor
naltrexone
fluoxetine
Prior art date
Application number
HR08/308,859A
Other languages
English (en)
Croatian (hr)
Inventor
Leonard Cook
Original Assignee
Du Pont Merck Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Du Pont Merck Pharma filed Critical Du Pont Merck Pharma
Publication of HRP950485A2 publication Critical patent/HRP950485A2/hr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/485Morphinan derivatives, e.g. morphine, codeine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32Alcohol-abuse

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Addiction (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Neurology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
HR08/308,859A 1994-09-19 1995-09-19 Combination of an opioid antagonist and a selective serotonin reuptake inhibitor for treatment of alcoholism and alcohol dependence HRP950485A2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US30885994A 1994-09-19 1994-09-19

Publications (1)

Publication Number Publication Date
HRP950485A2 true HRP950485A2 (en) 1997-08-31

Family

ID=23195683

Family Applications (1)

Application Number Title Priority Date Filing Date
HR08/308,859A HRP950485A2 (en) 1994-09-19 1995-09-19 Combination of an opioid antagonist and a selective serotonin reuptake inhibitor for treatment of alcoholism and alcohol dependence

Country Status (11)

Country Link
US (1) US5958962A (de)
EP (1) EP0782445B1 (de)
AT (1) ATE214276T1 (de)
AU (1) AU3419995A (de)
CA (1) CA2197554A1 (de)
CO (1) CO4410317A1 (de)
DE (1) DE69525847T2 (de)
DK (1) DK0782445T3 (de)
HR (1) HRP950485A2 (de)
WO (1) WO1996009047A1 (de)
ZA (1) ZA957891B (de)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6001848A (en) * 1996-03-25 1999-12-14 The Regents Of The University Of California Bromocriptine for the treatment of alcoholics diagnosed with the D2 dopamine receptor DRD2 A1 allele
SK180499A3 (en) 1997-07-01 2001-08-06 Pfizer Sertraline salts and sustained-release dosage forms of sertraline
ES2210760T3 (es) * 1997-07-01 2004-07-01 Pfizer Products Inc. Formas de dosificacion de seratina en solucion y encapsulada en gelatina.
WO2001032178A1 (en) * 1999-10-29 2001-05-10 Novo Nordisk A/S Use of 3,4-substituted piperidines
ES2540103T3 (es) * 2000-02-08 2015-07-08 Euro-Celtique S.A. Formulaciones orales de agonistas opioides resistentes a manipulaciones indebidas
US20040253627A1 (en) * 2000-07-07 2004-12-16 Grant Zimmermann System and method for multidimensional evaluation of combinations of compositions
US7034036B2 (en) * 2000-10-30 2006-04-25 Pain Therapeutics, Inc. Inhibitors of ABC drug transporters at the blood-brain barrier
EP1262196A3 (de) * 2001-05-23 2002-12-18 Pfizer Products Inc. Kombination eines Inhibitoren der Monoaminwiederaufnahme und eines Opioidanatagonisten zur Verwendung in Alkoholismus und Alkoholsucht
US7034059B2 (en) 2001-07-02 2006-04-25 Sepracor Inc. Methods of using norfluoxetine
HUP0401022A3 (en) * 2001-08-14 2006-11-28 Biotie Therapies Corp Method for the preparation of pharmaceutical compositions containing opioid antagonist for treating alcoholism or alcohol abuse
US20140271788A1 (en) 2013-03-15 2014-09-18 Monosol Rx, Llc Sublingual and buccal film compositions
US20050215552A1 (en) * 2002-05-17 2005-09-29 Gadde Kishore M Method for treating obesity
MXPA04011203A (es) * 2002-05-17 2005-07-14 Univ Duke Metodo para tratar la obesidad.
DE10237057A1 (de) * 2002-08-09 2004-03-25 Grünenthal GmbH Opioid-Rezeptor-Antagonisten in Pflasterformulierungen
WO2004096201A1 (en) 2003-04-29 2004-11-11 Orexigen Therapeutics, Inc. Compositions for affecting weight loss
EP1870096A3 (de) * 2003-04-29 2011-04-20 Orexigen Therapeutics, Inc. Zusammensetzungen zur Beeinflussung von Gewichtsverlust
US7713959B2 (en) * 2004-01-13 2010-05-11 Duke University Compositions of an anticonvulsant and mirtazapine to prevent weight gain
US20060160750A1 (en) * 2004-01-13 2006-07-20 Krishnan K R R Compositions of an anticonvulsant and an antipsychotic drug and methods of using the same for affecting weight loss
WO2005070461A2 (en) 2004-01-13 2005-08-04 Duke University Compositions of an anticonvulsant and an antipsychotic drug for affecting weight loss
US20060100205A1 (en) * 2004-04-21 2006-05-11 Eckard Weber Compositions for affecting weight loss
MX337422B (es) 2005-11-22 2016-03-04 Orexigen Therapeutics Inc Composiciones y metodos para incrementar la sencibilidad a la insulina.
WO2007089318A2 (en) * 2005-11-23 2007-08-09 Orexigen Therapeutics, Inc. Compositions and methods for reducing food cravings
WO2007064586A1 (en) * 2005-11-28 2007-06-07 Orexigen Therapeutics, Inc. Methods of treating anxiety disorders
US20070212307A1 (en) * 2006-02-10 2007-09-13 Daniel Wermeling Pharmaceutical Compositions Comprising an Opioid Receptor Antagonist and Methods of Using Same
US8916195B2 (en) 2006-06-05 2014-12-23 Orexigen Therapeutics, Inc. Sustained release formulation of naltrexone
KR20090090316A (ko) 2006-11-09 2009-08-25 오렉시젠 세러퓨틱스 인크. 체중 감량 약물을 투여하기 위한 단위 용량 팩키지 및 투여 방법
ATE460925T1 (de) 2006-11-09 2010-04-15 Orexigen Therapeutics Inc Mehrschichtige pharmazeutische formulierungen mit einer schnell auflösenden zwischenschicht
US9138430B2 (en) * 2007-12-27 2015-09-22 Mylan Specialty L.P. Formulation and method for the release of paroxetine in the large intestine
CA2725930A1 (en) 2008-05-30 2009-12-30 Orexigen Therapeutics, Inc. Methods for treating visceral fat conditions
US20100168119A1 (en) 2008-11-05 2010-07-01 Pharmorx, Inc. Compositions and methods for minimizing or reducing agonist-induced desensitization
CN102724878A (zh) 2010-01-11 2012-10-10 奥雷西根治疗公司 在重度抑郁症患者中提供体重减轻疗法的方法
KR20150016405A (ko) 2012-06-06 2015-02-11 오렉시젠 세러퓨틱스 인크. 과체중 및 비만의 치료 방법
US20150342946A1 (en) 2013-01-30 2015-12-03 Pharmorx Therapeutics, Inc. Treatments For Depression And Other Diseases With A Low Dose Agent
US8969371B1 (en) 2013-12-06 2015-03-03 Orexigen Therapeutics, Inc. Compositions and methods for weight loss in at risk patient populations
CA2875384A1 (en) 2013-12-20 2015-06-20 AntiOP, Inc. Intranasal naloxone compositions and methods of making and using same
AU2020245535B2 (en) 2019-03-26 2022-06-30 Pinova Therapeutics Inc. Devices and methods for delivering pharmaceutical compositions
US11278709B1 (en) 2021-03-12 2022-03-22 Pocket Naloxone Corp. Drug delivery device and methods for using same

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4777173A (en) * 1987-03-25 1988-10-11 Bristol-Myers Company Method for treatment of alcohol abuse
WO1992019241A1 (en) * 1991-05-07 1992-11-12 Dynagen, Inc. A controlled, sustained release delivery system for smoking cessation
US5366990A (en) * 1991-11-14 1994-11-22 Reid Larry D Method for treating alcohol abuse and alcoholism
US5512593A (en) * 1993-03-02 1996-04-30 John S. Nagle Composition and method of treating depression using natoxone or naltrexone in combination with a serotonin reuptake inhibitor

Also Published As

Publication number Publication date
WO1996009047A1 (en) 1996-03-28
CO4410317A1 (es) 1997-01-09
DE69525847D1 (de) 2002-04-18
EP0782445B1 (de) 2002-03-13
EP0782445A1 (de) 1997-07-09
DK0782445T3 (da) 2002-05-06
CA2197554A1 (en) 1996-03-28
US5958962A (en) 1999-09-28
DE69525847T2 (de) 2002-09-05
AU3419995A (en) 1996-04-09
ZA957891B (en) 1997-03-19
ATE214276T1 (de) 2002-03-15

Similar Documents

Publication Publication Date Title
HRP950485A2 (en) Combination of an opioid antagonist and a selective serotonin reuptake inhibitor for treatment of alcoholism and alcohol dependence
US6071918A (en) Combination of an opioid antagonist and a selective serotonin reuptake inhibitor for treatment of alcoholism and alcohol dependence
Mello et al. Buprenorphine suppresses cocaine self-administration by rhesus monkeys
US3966940A (en) Analgetic compositions
EP2612553B1 (de) Zusammensetzungen und Verfahren zur Vorbeugung und Behandlung von Suchtkrankheiten
US3773955A (en) Analgetic compositions
US4761429A (en) Enkephalinase and endorphinase inhibitors as anti-craving compositions
US3879555A (en) Method of treating drug addicts
US20250302771A1 (en) Treatment of opioid use disorder, opioid withdrawal symptoms and chronic pain
US8481599B2 (en) Compositions and methods for increasing compliance with therapies using aldehyde dehydrogenase inhibitors and treating alcoholism
AU740504B2 (en) Use of descarboethoxyloratadine for the manufacture of a medicament for the treatment of urinary incontinence, motion sickness and vertigo
Gardell et al. Combination of naltrexone and fluoxetine on rats’ propensity to take alcoholic beverage
Homayoun et al. The effect of cyclosporin A on morphine tolerance and dependence: involvement of L-arginine/nitric oxide pathway
US20250367189A1 (en) 2-bromo-lysergic acid diethylamide for substance abuse
EP1000623A1 (de) Gebrauch von epinastine als Antitussivum
AU1256501A (en) A method of treating substance addiction
Gardell et al. Luis zyxwvutsrqponmlkjihgfedcb
De Quincey high doses of pure agonists. 2 Such complex prop
Qureshi et al. Pharmacotherapies of addiction
Highfield Effects of Ng-nitro-L-arginine, a nitric oxide synthase inhibitor, on a cellular model of morphine tolerance
Short Evidence for an Endogenous Opioid Component in Nicotine Dependence and Abstinence Syndrome
Fekkes et al. Norharman and alcohol-dependency in male wistar rats
Cannoy-Searoy The Anti-Opiate Role of Neuropeptide FF in Narcotic Tolerance and Respiration
CA2114267A1 (en) Use of oxidase inhibitor with dextromethorphan to treat intractable coughing and dermatitis

Legal Events

Date Code Title Description
A1OB Publication of a patent application
AIPI Request for the grant of a patent on the basis of a substantive examination of a patent application
ODBI Application refused